In vitro secretion of cytokines and prostaglandin-E2 by monocytes from lung cancer patients
Monocytes (MO) from cancer patients present functional abnormalities, such as an altered secretion of soluble factors. In the present study, our aim was to evaluate the levels of interleukin-1β (IL-1β), tumour necrosis factor-alpha (TNF-α) and prostaglandin-E2 (PGE2) secreted in vitro by MO from lun...
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Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_09546111_v95_n4_p243_Trejo |
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todo:paper_09546111_v95_n4_p243_Trejo2023-10-03T15:51:45Z In vitro secretion of cytokines and prostaglandin-E2 by monocytes from lung cancer patients Trejo, Y.G. Bordenave, R.H. Beviacqua, M. Rumi, L.S. Il-1β Lung cancer Monocytes Pge2 Tna-α cytokine interleukin 1beta lipopolysaccharide prostaglandin E2 tumor necrosis factor alpha article cell secretion cell stimulation clinical article controlled study cytokine release human human cell in vitro study lung cancer monocyte priority journal prostaglandin release Monocytes (MO) from cancer patients present functional abnormalities, such as an altered secretion of soluble factors. In the present study, our aim was to evaluate the levels of interleukin-1β (IL-1β), tumour necrosis factor-alpha (TNF-α) and prostaglandin-E2 (PGE2) secreted in vitro by MO from lung cancer patients (LCP), spontaneously or after stimulation with lipopolysaccharide (LPS). Results showed that cytokine secretion was higher for MO from LCP than for MO from healthy controls, while in the 25% of the patients analysed, an absence of response to LPS treatment was found. © 2001 Harcourt Publishers Ltd. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_09546111_v95_n4_p243_Trejo |
institution |
Universidad de Buenos Aires |
institution_str |
I-28 |
repository_str |
R-134 |
collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
topic |
Il-1β Lung cancer Monocytes Pge2 Tna-α cytokine interleukin 1beta lipopolysaccharide prostaglandin E2 tumor necrosis factor alpha article cell secretion cell stimulation clinical article controlled study cytokine release human human cell in vitro study lung cancer monocyte priority journal prostaglandin release |
spellingShingle |
Il-1β Lung cancer Monocytes Pge2 Tna-α cytokine interleukin 1beta lipopolysaccharide prostaglandin E2 tumor necrosis factor alpha article cell secretion cell stimulation clinical article controlled study cytokine release human human cell in vitro study lung cancer monocyte priority journal prostaglandin release Trejo, Y.G. Bordenave, R.H. Beviacqua, M. Rumi, L.S. In vitro secretion of cytokines and prostaglandin-E2 by monocytes from lung cancer patients |
topic_facet |
Il-1β Lung cancer Monocytes Pge2 Tna-α cytokine interleukin 1beta lipopolysaccharide prostaglandin E2 tumor necrosis factor alpha article cell secretion cell stimulation clinical article controlled study cytokine release human human cell in vitro study lung cancer monocyte priority journal prostaglandin release |
description |
Monocytes (MO) from cancer patients present functional abnormalities, such as an altered secretion of soluble factors. In the present study, our aim was to evaluate the levels of interleukin-1β (IL-1β), tumour necrosis factor-alpha (TNF-α) and prostaglandin-E2 (PGE2) secreted in vitro by MO from lung cancer patients (LCP), spontaneously or after stimulation with lipopolysaccharide (LPS). Results showed that cytokine secretion was higher for MO from LCP than for MO from healthy controls, while in the 25% of the patients analysed, an absence of response to LPS treatment was found. © 2001 Harcourt Publishers Ltd. |
format |
JOUR |
author |
Trejo, Y.G. Bordenave, R.H. Beviacqua, M. Rumi, L.S. |
author_facet |
Trejo, Y.G. Bordenave, R.H. Beviacqua, M. Rumi, L.S. |
author_sort |
Trejo, Y.G. |
title |
In vitro secretion of cytokines and prostaglandin-E2 by monocytes from lung cancer patients |
title_short |
In vitro secretion of cytokines and prostaglandin-E2 by monocytes from lung cancer patients |
title_full |
In vitro secretion of cytokines and prostaglandin-E2 by monocytes from lung cancer patients |
title_fullStr |
In vitro secretion of cytokines and prostaglandin-E2 by monocytes from lung cancer patients |
title_full_unstemmed |
In vitro secretion of cytokines and prostaglandin-E2 by monocytes from lung cancer patients |
title_sort |
in vitro secretion of cytokines and prostaglandin-e2 by monocytes from lung cancer patients |
url |
http://hdl.handle.net/20.500.12110/paper_09546111_v95_n4_p243_Trejo |
work_keys_str_mv |
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_version_ |
1807314485487075328 |