In vitro secretion of cytokines and prostaglandin-E2 by monocytes from lung cancer patients

Monocytes (MO) from cancer patients present functional abnormalities, such as an altered secretion of soluble factors. In the present study, our aim was to evaluate the levels of interleukin-1β (IL-1β), tumour necrosis factor-alpha (TNF-α) and prostaglandin-E2 (PGE2) secreted in vitro by MO from lun...

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Autores principales: Trejo, Y.G., Bordenave, R.H., Beviacqua, M., Rumi, L.S.
Formato: JOUR
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Acceso en línea:http://hdl.handle.net/20.500.12110/paper_09546111_v95_n4_p243_Trejo
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spelling todo:paper_09546111_v95_n4_p243_Trejo2023-10-03T15:51:45Z In vitro secretion of cytokines and prostaglandin-E2 by monocytes from lung cancer patients Trejo, Y.G. Bordenave, R.H. Beviacqua, M. Rumi, L.S. Il-1β Lung cancer Monocytes Pge2 Tna-α cytokine interleukin 1beta lipopolysaccharide prostaglandin E2 tumor necrosis factor alpha article cell secretion cell stimulation clinical article controlled study cytokine release human human cell in vitro study lung cancer monocyte priority journal prostaglandin release Monocytes (MO) from cancer patients present functional abnormalities, such as an altered secretion of soluble factors. In the present study, our aim was to evaluate the levels of interleukin-1β (IL-1β), tumour necrosis factor-alpha (TNF-α) and prostaglandin-E2 (PGE2) secreted in vitro by MO from lung cancer patients (LCP), spontaneously or after stimulation with lipopolysaccharide (LPS). Results showed that cytokine secretion was higher for MO from LCP than for MO from healthy controls, while in the 25% of the patients analysed, an absence of response to LPS treatment was found. © 2001 Harcourt Publishers Ltd. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_09546111_v95_n4_p243_Trejo
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic Il-1β
Lung cancer
Monocytes
Pge2
Tna-α
cytokine
interleukin 1beta
lipopolysaccharide
prostaglandin E2
tumor necrosis factor alpha
article
cell secretion
cell stimulation
clinical article
controlled study
cytokine release
human
human cell
in vitro study
lung cancer
monocyte
priority journal
prostaglandin release
spellingShingle Il-1β
Lung cancer
Monocytes
Pge2
Tna-α
cytokine
interleukin 1beta
lipopolysaccharide
prostaglandin E2
tumor necrosis factor alpha
article
cell secretion
cell stimulation
clinical article
controlled study
cytokine release
human
human cell
in vitro study
lung cancer
monocyte
priority journal
prostaglandin release
Trejo, Y.G.
Bordenave, R.H.
Beviacqua, M.
Rumi, L.S.
In vitro secretion of cytokines and prostaglandin-E2 by monocytes from lung cancer patients
topic_facet Il-1β
Lung cancer
Monocytes
Pge2
Tna-α
cytokine
interleukin 1beta
lipopolysaccharide
prostaglandin E2
tumor necrosis factor alpha
article
cell secretion
cell stimulation
clinical article
controlled study
cytokine release
human
human cell
in vitro study
lung cancer
monocyte
priority journal
prostaglandin release
description Monocytes (MO) from cancer patients present functional abnormalities, such as an altered secretion of soluble factors. In the present study, our aim was to evaluate the levels of interleukin-1β (IL-1β), tumour necrosis factor-alpha (TNF-α) and prostaglandin-E2 (PGE2) secreted in vitro by MO from lung cancer patients (LCP), spontaneously or after stimulation with lipopolysaccharide (LPS). Results showed that cytokine secretion was higher for MO from LCP than for MO from healthy controls, while in the 25% of the patients analysed, an absence of response to LPS treatment was found. © 2001 Harcourt Publishers Ltd.
format JOUR
author Trejo, Y.G.
Bordenave, R.H.
Beviacqua, M.
Rumi, L.S.
author_facet Trejo, Y.G.
Bordenave, R.H.
Beviacqua, M.
Rumi, L.S.
author_sort Trejo, Y.G.
title In vitro secretion of cytokines and prostaglandin-E2 by monocytes from lung cancer patients
title_short In vitro secretion of cytokines and prostaglandin-E2 by monocytes from lung cancer patients
title_full In vitro secretion of cytokines and prostaglandin-E2 by monocytes from lung cancer patients
title_fullStr In vitro secretion of cytokines and prostaglandin-E2 by monocytes from lung cancer patients
title_full_unstemmed In vitro secretion of cytokines and prostaglandin-E2 by monocytes from lung cancer patients
title_sort in vitro secretion of cytokines and prostaglandin-e2 by monocytes from lung cancer patients
url http://hdl.handle.net/20.500.12110/paper_09546111_v95_n4_p243_Trejo
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AT bordenaverh invitrosecretionofcytokinesandprostaglandine2bymonocytesfromlungcancerpatients
AT beviacquam invitrosecretionofcytokinesandprostaglandine2bymonocytesfromlungcancerpatients
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