Early olfactory experience modifies neural activity in the antennal lobe of a social insect at the adult stage
In the antennal lobe (AL), the first olfactory centre of the insect brain, odorants are represented as spatiotemporal patterns of glomerular activity. Whether and how such patterns are modified in the long term after precocious olfactory experiences (i.e. in the first days of adulthood) remains unkn...
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| Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_0953816X_v30_n8_p1498_Arenas |
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todo:paper_0953816X_v30_n8_p1498_Arenas2023-10-03T15:51:18Z Early olfactory experience modifies neural activity in the antennal lobe of a social insect at the adult stage Arenas, A. Giurfa, M. Farina, W.M. Sandoz, J.C. Associative learning Early experiences Honeybee Memory retrieval Olfaction Optical imaging calcium carbon animal experiment antenna article brain function controlled study glomerulus honeybee in vivo study insect society nerve cell nerve potential nonhuman odor olfactory system priority journal stimulus response Animals Association Learning Bees Behavior, Animal Brain Mapping Calcium Calcium Signaling Conditioning, Classical Odors Olfactory Pathways Sense Organs Sensory Receptor Cells Smell Social Behavior Statistics as Topic In the antennal lobe (AL), the first olfactory centre of the insect brain, odorants are represented as spatiotemporal patterns of glomerular activity. Whether and how such patterns are modified in the long term after precocious olfactory experiences (i.e. in the first days of adulthood) remains unknown. To address this question, we used in vivo optical imaging of calcium activity in the antennal lobe of 17-day-old honeybees which either experienced an odorant associated with sucrose solution 5-8 days after emergence or were left untreated. In both cases, we imaged neural responses to the learned odor and to three novel odors varying in functional group and carbon-chain length. Two different odor concentrations were used. We also measured behavioral responses of 17-day-old honeybees, treated and untreated, to these stimuli. We show that precocious olfactory experience increased general odor-induced activity and the number of activated glomeruli in the adult AL, but also affected qualitative odor representations, which appeared shifted in the neural space of treated animals relative to control animals. Such effects were not limited to the experienced odor, but were generalized to other perceptually similar odors. A similar trend was found in behavioral experiments, in which increased responses to the learned odor extended to perceptually similar odors in treated bees. Our results show that early olfactory experiences have long-lasting effects, reflected in behavioral responses to odorants and concomitant neural activity in the adult olfactory system. © 2009 Federation of European Neuroscience Societies and Blackwell Publishing Ltd. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_0953816X_v30_n8_p1498_Arenas |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
Associative learning Early experiences Honeybee Memory retrieval Olfaction Optical imaging calcium carbon animal experiment antenna article brain function controlled study glomerulus honeybee in vivo study insect society nerve cell nerve potential nonhuman odor olfactory system priority journal stimulus response Animals Association Learning Bees Behavior, Animal Brain Mapping Calcium Calcium Signaling Conditioning, Classical Odors Olfactory Pathways Sense Organs Sensory Receptor Cells Smell Social Behavior Statistics as Topic |
| spellingShingle |
Associative learning Early experiences Honeybee Memory retrieval Olfaction Optical imaging calcium carbon animal experiment antenna article brain function controlled study glomerulus honeybee in vivo study insect society nerve cell nerve potential nonhuman odor olfactory system priority journal stimulus response Animals Association Learning Bees Behavior, Animal Brain Mapping Calcium Calcium Signaling Conditioning, Classical Odors Olfactory Pathways Sense Organs Sensory Receptor Cells Smell Social Behavior Statistics as Topic Arenas, A. Giurfa, M. Farina, W.M. Sandoz, J.C. Early olfactory experience modifies neural activity in the antennal lobe of a social insect at the adult stage |
| topic_facet |
Associative learning Early experiences Honeybee Memory retrieval Olfaction Optical imaging calcium carbon animal experiment antenna article brain function controlled study glomerulus honeybee in vivo study insect society nerve cell nerve potential nonhuman odor olfactory system priority journal stimulus response Animals Association Learning Bees Behavior, Animal Brain Mapping Calcium Calcium Signaling Conditioning, Classical Odors Olfactory Pathways Sense Organs Sensory Receptor Cells Smell Social Behavior Statistics as Topic |
| description |
In the antennal lobe (AL), the first olfactory centre of the insect brain, odorants are represented as spatiotemporal patterns of glomerular activity. Whether and how such patterns are modified in the long term after precocious olfactory experiences (i.e. in the first days of adulthood) remains unknown. To address this question, we used in vivo optical imaging of calcium activity in the antennal lobe of 17-day-old honeybees which either experienced an odorant associated with sucrose solution 5-8 days after emergence or were left untreated. In both cases, we imaged neural responses to the learned odor and to three novel odors varying in functional group and carbon-chain length. Two different odor concentrations were used. We also measured behavioral responses of 17-day-old honeybees, treated and untreated, to these stimuli. We show that precocious olfactory experience increased general odor-induced activity and the number of activated glomeruli in the adult AL, but also affected qualitative odor representations, which appeared shifted in the neural space of treated animals relative to control animals. Such effects were not limited to the experienced odor, but were generalized to other perceptually similar odors. A similar trend was found in behavioral experiments, in which increased responses to the learned odor extended to perceptually similar odors in treated bees. Our results show that early olfactory experiences have long-lasting effects, reflected in behavioral responses to odorants and concomitant neural activity in the adult olfactory system. © 2009 Federation of European Neuroscience Societies and Blackwell Publishing Ltd. |
| format |
JOUR |
| author |
Arenas, A. Giurfa, M. Farina, W.M. Sandoz, J.C. |
| author_facet |
Arenas, A. Giurfa, M. Farina, W.M. Sandoz, J.C. |
| author_sort |
Arenas, A. |
| title |
Early olfactory experience modifies neural activity in the antennal lobe of a social insect at the adult stage |
| title_short |
Early olfactory experience modifies neural activity in the antennal lobe of a social insect at the adult stage |
| title_full |
Early olfactory experience modifies neural activity in the antennal lobe of a social insect at the adult stage |
| title_fullStr |
Early olfactory experience modifies neural activity in the antennal lobe of a social insect at the adult stage |
| title_full_unstemmed |
Early olfactory experience modifies neural activity in the antennal lobe of a social insect at the adult stage |
| title_sort |
early olfactory experience modifies neural activity in the antennal lobe of a social insect at the adult stage |
| url |
http://hdl.handle.net/20.500.12110/paper_0953816X_v30_n8_p1498_Arenas |
| work_keys_str_mv |
AT arenasa earlyolfactoryexperiencemodifiesneuralactivityintheantennallobeofasocialinsectattheadultstage AT giurfam earlyolfactoryexperiencemodifiesneuralactivityintheantennallobeofasocialinsectattheadultstage AT farinawm earlyolfactoryexperiencemodifiesneuralactivityintheantennallobeofasocialinsectattheadultstage AT sandozjc earlyolfactoryexperiencemodifiesneuralactivityintheantennallobeofasocialinsectattheadultstage |
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1807315211882856448 |