A galectin-specific signature in the gut delineates Crohn's disease and ulcerative colitis from other human inflammatory intestinal disorders

Inflammatory bowel diseases (IBD) are chronic and relapsing inflammatory conditions of the gastrointestinal tract including Crohn's disease (CD) and ulcerative colitis (UC). Galectins, defined by shared consensus amino acid sequence and affinity for β-galactosides, are critical modulators of th...

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Detalles Bibliográficos
Autores principales: Papa Gobbi, R., De Francesco, N., Bondar, C., Muglia, C., Chirdo, F., Rumbo, M., Rocca, A., Toscano, M.A., Sambuelli, A., Rabinovich, G.A., Docena, G.H.
Formato: JOUR
Materias:
Biomarkers
Crohn disease
Galectins
Inflammatory bowel diseases
Ulcerative colitis
ecalectin
galectin
galectin 3
galectin 4
messenger RNA
1-nitrohydroxyphenyl-N-benzoylalanine
benzamide derivative
LGALS9 protein, human
tyrosine
adult
aged
Article
colon biopsy
controlled study
discriminant analysis
enteropathy
female
human
human tissue
inflammation
intestine
major clinical study
male
priority journal
protein expression
quantitative analysis
remission
reverse transcription polymerase chain reaction
ulcerative colitis
analogs and derivatives
biopsy
biosynthesis
gastrointestinal tract
gene expression regulation
genetics
intestine mucosa
metabolism
pathology
Adult
Benzamides
Biopsy
Colitis, Ulcerative
Crohn Disease
Female
Galectin 3
Galectin 4
Gastrointestinal Tract
Gene Expression Regulation
Humans
Inflammation
Intestinal Mucosa
Intestines
Male
RNA, Messenger
Tyrosine
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_09516433_v42_n1_p93_PapaGobbi
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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