Virucidal activity in aqueous extracts obtained from Cedrela tubiflora leaves
Crude extracts obtained from leaves of Cedrela tubiflora (CT) (Meliaceae family) show antiviral and virucidal effects against several viruses. Herpes simplex, pseudorabies and vesicular stomatitis viruses were extremely susceptible and a reduction of 3–5 log in infectivity occurred after 15 min of d...
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| Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_0951418X_v5_n6_p250_Cordoba |
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todo:paper_0951418X_v5_n6_p250_Cordoba2023-10-03T15:50:39Z Virucidal activity in aqueous extracts obtained from Cedrela tubiflora leaves Cordoba, M.A. Coto, C.E. Damonte, E.B. Cedrela tubiflora herpes‐virus Meliaceae plant antiviral vesicular stomatitis virus virucidal activity cedrela tubiflora extract plant extract unclassified drug animal cell antiviral activity article controlled study cytotoxicity herpes simplex virus 1 nonhuman plant leaf poliomyelitis virus pseudorabies herpetovirus vero cell vesicular stomatitis virus Animalia Arenavirus Cedrela Cedrela tubiflora Herpes herpetovirus Human herpesvirus 1 Meliaceae Poliovirus Suid herpesvirus 1 Vesicular stomatitis virus Crude extracts obtained from leaves of Cedrela tubiflora (CT) (Meliaceae family) show antiviral and virucidal effects against several viruses. Herpes simplex, pseudorabies and vesicular stomatitis viruses were extremely susceptible and a reduction of 3–5 log in infectivity occurred after 15 min of direct incubation with the plant extract. By contrast, poliovirus and the Tacaribe arenavirus are inhibited intracellularly. The inhibitory action is dose dependent and no cytotoxic effects were detected on Vero cells after 2 days of CT treatment. Copyright © 1991 John Wiley & Sons, Ltd. Fil:Coto, C.E. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Damonte, E.B. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_0951418X_v5_n6_p250_Cordoba |
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Universidad de Buenos Aires |
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I-28 |
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R-134 |
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Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
Cedrela tubiflora herpes‐virus Meliaceae plant antiviral vesicular stomatitis virus virucidal activity cedrela tubiflora extract plant extract unclassified drug animal cell antiviral activity article controlled study cytotoxicity herpes simplex virus 1 nonhuman plant leaf poliomyelitis virus pseudorabies herpetovirus vero cell vesicular stomatitis virus Animalia Arenavirus Cedrela Cedrela tubiflora Herpes herpetovirus Human herpesvirus 1 Meliaceae Poliovirus Suid herpesvirus 1 Vesicular stomatitis virus |
| spellingShingle |
Cedrela tubiflora herpes‐virus Meliaceae plant antiviral vesicular stomatitis virus virucidal activity cedrela tubiflora extract plant extract unclassified drug animal cell antiviral activity article controlled study cytotoxicity herpes simplex virus 1 nonhuman plant leaf poliomyelitis virus pseudorabies herpetovirus vero cell vesicular stomatitis virus Animalia Arenavirus Cedrela Cedrela tubiflora Herpes herpetovirus Human herpesvirus 1 Meliaceae Poliovirus Suid herpesvirus 1 Vesicular stomatitis virus Cordoba, M.A. Coto, C.E. Damonte, E.B. Virucidal activity in aqueous extracts obtained from Cedrela tubiflora leaves |
| topic_facet |
Cedrela tubiflora herpes‐virus Meliaceae plant antiviral vesicular stomatitis virus virucidal activity cedrela tubiflora extract plant extract unclassified drug animal cell antiviral activity article controlled study cytotoxicity herpes simplex virus 1 nonhuman plant leaf poliomyelitis virus pseudorabies herpetovirus vero cell vesicular stomatitis virus Animalia Arenavirus Cedrela Cedrela tubiflora Herpes herpetovirus Human herpesvirus 1 Meliaceae Poliovirus Suid herpesvirus 1 Vesicular stomatitis virus |
| description |
Crude extracts obtained from leaves of Cedrela tubiflora (CT) (Meliaceae family) show antiviral and virucidal effects against several viruses. Herpes simplex, pseudorabies and vesicular stomatitis viruses were extremely susceptible and a reduction of 3–5 log in infectivity occurred after 15 min of direct incubation with the plant extract. By contrast, poliovirus and the Tacaribe arenavirus are inhibited intracellularly. The inhibitory action is dose dependent and no cytotoxic effects were detected on Vero cells after 2 days of CT treatment. Copyright © 1991 John Wiley & Sons, Ltd. |
| format |
JOUR |
| author |
Cordoba, M.A. Coto, C.E. Damonte, E.B. |
| author_facet |
Cordoba, M.A. Coto, C.E. Damonte, E.B. |
| author_sort |
Cordoba, M.A. |
| title |
Virucidal activity in aqueous extracts obtained from Cedrela tubiflora leaves |
| title_short |
Virucidal activity in aqueous extracts obtained from Cedrela tubiflora leaves |
| title_full |
Virucidal activity in aqueous extracts obtained from Cedrela tubiflora leaves |
| title_fullStr |
Virucidal activity in aqueous extracts obtained from Cedrela tubiflora leaves |
| title_full_unstemmed |
Virucidal activity in aqueous extracts obtained from Cedrela tubiflora leaves |
| title_sort |
virucidal activity in aqueous extracts obtained from cedrela tubiflora leaves |
| url |
http://hdl.handle.net/20.500.12110/paper_0951418X_v5_n6_p250_Cordoba |
| work_keys_str_mv |
AT cordobama virucidalactivityinaqueousextractsobtainedfromcedrelatubifloraleaves AT cotoce virucidalactivityinaqueousextractsobtainedfromcedrelatubifloraleaves AT damonteeb virucidalactivityinaqueousextractsobtainedfromcedrelatubifloraleaves |
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