An antiviral meliacarpin from leaves of Melia azedarach L.
Bioassay guided purification of the ethyl acetate extract of leaves of Melia azedarach led to the isolation of the limonoid 1-cinnamoyl-3,11-dihydroxymeliacarpin, which showed IC50 values of 6 μM and 20 μM for vesicular stomatitis (VSV) and herpes simplex (HSV-1) viruses, respectively. Its structure...
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| Formato: | JOUR |
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| Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_09395075_v58_n3-4_p215_Alche |
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todo:paper_09395075_v58_n3-4_p215_Alche2023-10-03T15:48:51Z An antiviral meliacarpin from leaves of Melia azedarach L. Alché, L.E. Ferek, G.A. Meo, M. Coto, C.E. Maier, M.S. Antiviral Activity Limonoids Melia azedarach L. Melia azedarach Melia azedarach Simplexvirus Vesicular stomatitis virus Bioassay guided purification of the ethyl acetate extract of leaves of Melia azedarach led to the isolation of the limonoid 1-cinnamoyl-3,11-dihydroxymeliacarpin, which showed IC50 values of 6 μM and 20 μM for vesicular stomatitis (VSV) and herpes simplex (HSV-1) viruses, respectively. Its structure was established by spectroscopic methods. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_09395075_v58_n3-4_p215_Alche |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
Antiviral Activity Limonoids Melia azedarach L. Melia azedarach Melia azedarach Simplexvirus Vesicular stomatitis virus |
| spellingShingle |
Antiviral Activity Limonoids Melia azedarach L. Melia azedarach Melia azedarach Simplexvirus Vesicular stomatitis virus Alché, L.E. Ferek, G.A. Meo, M. Coto, C.E. Maier, M.S. An antiviral meliacarpin from leaves of Melia azedarach L. |
| topic_facet |
Antiviral Activity Limonoids Melia azedarach L. Melia azedarach Melia azedarach Simplexvirus Vesicular stomatitis virus |
| description |
Bioassay guided purification of the ethyl acetate extract of leaves of Melia azedarach led to the isolation of the limonoid 1-cinnamoyl-3,11-dihydroxymeliacarpin, which showed IC50 values of 6 μM and 20 μM for vesicular stomatitis (VSV) and herpes simplex (HSV-1) viruses, respectively. Its structure was established by spectroscopic methods. |
| format |
JOUR |
| author |
Alché, L.E. Ferek, G.A. Meo, M. Coto, C.E. Maier, M.S. |
| author_facet |
Alché, L.E. Ferek, G.A. Meo, M. Coto, C.E. Maier, M.S. |
| author_sort |
Alché, L.E. |
| title |
An antiviral meliacarpin from leaves of Melia azedarach L. |
| title_short |
An antiviral meliacarpin from leaves of Melia azedarach L. |
| title_full |
An antiviral meliacarpin from leaves of Melia azedarach L. |
| title_fullStr |
An antiviral meliacarpin from leaves of Melia azedarach L. |
| title_full_unstemmed |
An antiviral meliacarpin from leaves of Melia azedarach L. |
| title_sort |
antiviral meliacarpin from leaves of melia azedarach l. |
| url |
http://hdl.handle.net/20.500.12110/paper_09395075_v58_n3-4_p215_Alche |
| work_keys_str_mv |
AT alchele anantiviralmeliacarpinfromleavesofmeliaazedarachl AT ferekga anantiviralmeliacarpinfromleavesofmeliaazedarachl AT meom anantiviralmeliacarpinfromleavesofmeliaazedarachl AT cotoce anantiviralmeliacarpinfromleavesofmeliaazedarachl AT maierms anantiviralmeliacarpinfromleavesofmeliaazedarachl AT alchele antiviralmeliacarpinfromleavesofmeliaazedarachl AT ferekga antiviralmeliacarpinfromleavesofmeliaazedarachl AT meom antiviralmeliacarpinfromleavesofmeliaazedarachl AT cotoce antiviralmeliacarpinfromleavesofmeliaazedarachl AT maierms antiviralmeliacarpinfromleavesofmeliaazedarachl |
| _version_ |
1782023787564236800 |