Synthesis and Activity of Juvenile Hormone Analogues (JHA)

From geranylacetone and by the use of a variety of reagents, twelve analogues of the juvenile hormone III were synthesized. The compounds (5—16) have an isoprenic structure bearing at the extreme of the chain functional groups as carbonate, carbamate, thiolcarbonate, thiolcarbamate, carbonyloxyimino...

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Autores principales: Rodriguez, J.B., Gros, E.G., Stoka, A.M.
Formato: JOUR
Materias:
Activity
Juvenile Hormone Analogues
Synthesis
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_09320776_v43_n8_p1038_Rodriguez
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Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
id todo:paper_09320776_v43_n8_p1038_Rodriguez
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spelling todo:paper_09320776_v43_n8_p1038_Rodriguez2023-10-03T15:48:24Z Synthesis and Activity of Juvenile Hormone Analogues (JHA) Rodriguez, J.B. Gros, E.G. Stoka, A.M. Activity Juvenile Hormone Analogues Synthesis From geranylacetone and by the use of a variety of reagents, twelve analogues of the juvenile hormone III were synthesized. The compounds (5—16) have an isoprenic structure bearing at the extreme of the chain functional groups as carbonate, carbamate, thiolcarbonate, thiolcarbamate, carbonyloxyimino and thiol carbonyloxyimino. Compounds 5—9 present the normal unsaturated isoprenic chain while compounds 10—16 have a monoepoxide function. All the compounds were tested for their respective juvenile hormone activity for Triatoma infestans and Rhodniusprolixus. The most active compounds were those having a thiol carbonate group independently of the oxidation state of the molecule. The synthetic procedures and the biological results are discussed. © 1988, Walter de Gruyter. All rights reserved. Fil:Rodriguez, J.B. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Gros, E.G. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Stoka, A.M. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_09320776_v43_n8_p1038_Rodriguez
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic Activity
Juvenile Hormone Analogues
Synthesis
spellingShingle Activity
Juvenile Hormone Analogues
Synthesis
Rodriguez, J.B.
Gros, E.G.
Stoka, A.M.
Synthesis and Activity of Juvenile Hormone Analogues (JHA)
topic_facet Activity
Juvenile Hormone Analogues
Synthesis
description From geranylacetone and by the use of a variety of reagents, twelve analogues of the juvenile hormone III were synthesized. The compounds (5—16) have an isoprenic structure bearing at the extreme of the chain functional groups as carbonate, carbamate, thiolcarbonate, thiolcarbamate, carbonyloxyimino and thiol carbonyloxyimino. Compounds 5—9 present the normal unsaturated isoprenic chain while compounds 10—16 have a monoepoxide function. All the compounds were tested for their respective juvenile hormone activity for Triatoma infestans and Rhodniusprolixus. The most active compounds were those having a thiol carbonate group independently of the oxidation state of the molecule. The synthetic procedures and the biological results are discussed. © 1988, Walter de Gruyter. All rights reserved.
format JOUR
author Rodriguez, J.B.
Gros, E.G.
Stoka, A.M.
author_facet Rodriguez, J.B.
Gros, E.G.
Stoka, A.M.
author_sort Rodriguez, J.B.
title Synthesis and Activity of Juvenile Hormone Analogues (JHA)
title_short Synthesis and Activity of Juvenile Hormone Analogues (JHA)
title_full Synthesis and Activity of Juvenile Hormone Analogues (JHA)
title_fullStr Synthesis and Activity of Juvenile Hormone Analogues (JHA)
title_full_unstemmed Synthesis and Activity of Juvenile Hormone Analogues (JHA)
title_sort synthesis and activity of juvenile hormone analogues (jha)
url http://hdl.handle.net/20.500.12110/paper_09320776_v43_n8_p1038_Rodriguez
work_keys_str_mv AT rodriguezjb synthesisandactivityofjuvenilehormoneanaloguesjha
AT groseg synthesisandactivityofjuvenilehormoneanaloguesjha
AT stokaam synthesisandactivityofjuvenilehormoneanaloguesjha
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