Cryografts implantation in human circulation would ensure a physiological transition in the arterial wall energetics, damping and wave reflection
As Each artery conduces blood (conduit function, CF) and smoothes out the pulsatility (buffering function, BF), while keeping its wall protected against the high oscillations of the pulse waves (damping function, ξ). These functions depend on each segment viscoelasticity and capability to store and...
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| Lenguaje: | English |
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| Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_08628408_v57_n3_p351_SantanaBia |
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todo:paper_08628408_v57_n3_p351_SantanaBia2023-10-03T15:40:18Z Cryografts implantation in human circulation would ensure a physiological transition in the arterial wall energetics, damping and wave reflection Santana Bia, D. Barra, J.G. Armentano, R.L. Zócalo, Y. Pérez, H. Saldías, M. Álvarez, I. Cabrera Fischer, E.I. Arterial wall Buffer function Conduit function Cryopreservation Viscoelasticity adult article biological model bioprosthesis blood pressure blood vessel prosthesis blood vessel transplantation common carotid artery cryopreservation echography elasticity heart rate human instrumentation male materials testing mechanical stress middle aged physiology prosthesis pulsatile flow transplantation Adult Bioprosthesis Blood Pressure Blood Vessel Prosthesis Blood Vessel Prosthesis Implantation Carotid Artery, Common Cryopreservation Elasticity Heart Rate Humans Male Materials Testing Middle Aged Models, Cardiovascular Prosthesis Design Pulsatile Flow Stress, Mechanical As Each artery conduces blood (conduit function, CF) and smoothes out the pulsatility (buffering function, BF), while keeping its wall protected against the high oscillations of the pulse waves (damping function, ξ). These functions depend on each segment viscoelasticity and capability to store and dissipate energy. When a graft/prosthesis is implanted, the physiological gradual transition in the viscoelasticity and functionality of adjacent arterial segments is disrupted. It remains to be elucidated if the cryografts would allow keeping the physiological biomechanical transition. The aim of this study was to evaluate the cryografts capability to reproduce the functional, energetic and reflection properties of patients' arteries and fresh homografts. Common carotid's pressure, diameter and wall-thickness were recorded in vivo (15 patients) and in vitro (15 cryografts and 15 fresh homografts from donors). Calculus: elastic (Epd) and viscous (Vpd) indexes, CF, BF, dissipated (WD) and stored (WPS) energy and ξ. The graft-patient's artery matching was evaluated using the reflection coefficient (?) and reflected power (W?). Cryografts did not show differences in Epd, Vpd, BF, CF, WD, WPS, and ξ, in respect to fresh homografts and patients' arteries, ensuring a reduced Γ and WΓ. Cryografts could be considered as alternatives in arterial reconstructions since they ensure the gradual transition of patients' arteries biomechanical and functional behavior. © 2008 Institute of Physiology v.v.i., Academy of Sciences of the Czech Republic. JOUR English info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_08628408_v57_n3_p351_SantanaBia |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| language |
English |
| orig_language_str_mv |
English |
| topic |
Arterial wall Buffer function Conduit function Cryopreservation Viscoelasticity adult article biological model bioprosthesis blood pressure blood vessel prosthesis blood vessel transplantation common carotid artery cryopreservation echography elasticity heart rate human instrumentation male materials testing mechanical stress middle aged physiology prosthesis pulsatile flow transplantation Adult Bioprosthesis Blood Pressure Blood Vessel Prosthesis Blood Vessel Prosthesis Implantation Carotid Artery, Common Cryopreservation Elasticity Heart Rate Humans Male Materials Testing Middle Aged Models, Cardiovascular Prosthesis Design Pulsatile Flow Stress, Mechanical |
| spellingShingle |
Arterial wall Buffer function Conduit function Cryopreservation Viscoelasticity adult article biological model bioprosthesis blood pressure blood vessel prosthesis blood vessel transplantation common carotid artery cryopreservation echography elasticity heart rate human instrumentation male materials testing mechanical stress middle aged physiology prosthesis pulsatile flow transplantation Adult Bioprosthesis Blood Pressure Blood Vessel Prosthesis Blood Vessel Prosthesis Implantation Carotid Artery, Common Cryopreservation Elasticity Heart Rate Humans Male Materials Testing Middle Aged Models, Cardiovascular Prosthesis Design Pulsatile Flow Stress, Mechanical Santana Bia, D. Barra, J.G. Armentano, R.L. Zócalo, Y. Pérez, H. Saldías, M. Álvarez, I. Cabrera Fischer, E.I. Cryografts implantation in human circulation would ensure a physiological transition in the arterial wall energetics, damping and wave reflection |
| topic_facet |
Arterial wall Buffer function Conduit function Cryopreservation Viscoelasticity adult article biological model bioprosthesis blood pressure blood vessel prosthesis blood vessel transplantation common carotid artery cryopreservation echography elasticity heart rate human instrumentation male materials testing mechanical stress middle aged physiology prosthesis pulsatile flow transplantation Adult Bioprosthesis Blood Pressure Blood Vessel Prosthesis Blood Vessel Prosthesis Implantation Carotid Artery, Common Cryopreservation Elasticity Heart Rate Humans Male Materials Testing Middle Aged Models, Cardiovascular Prosthesis Design Pulsatile Flow Stress, Mechanical |
| description |
As Each artery conduces blood (conduit function, CF) and smoothes out the pulsatility (buffering function, BF), while keeping its wall protected against the high oscillations of the pulse waves (damping function, ξ). These functions depend on each segment viscoelasticity and capability to store and dissipate energy. When a graft/prosthesis is implanted, the physiological gradual transition in the viscoelasticity and functionality of adjacent arterial segments is disrupted. It remains to be elucidated if the cryografts would allow keeping the physiological biomechanical transition. The aim of this study was to evaluate the cryografts capability to reproduce the functional, energetic and reflection properties of patients' arteries and fresh homografts. Common carotid's pressure, diameter and wall-thickness were recorded in vivo (15 patients) and in vitro (15 cryografts and 15 fresh homografts from donors). Calculus: elastic (Epd) and viscous (Vpd) indexes, CF, BF, dissipated (WD) and stored (WPS) energy and ξ. The graft-patient's artery matching was evaluated using the reflection coefficient (?) and reflected power (W?). Cryografts did not show differences in Epd, Vpd, BF, CF, WD, WPS, and ξ, in respect to fresh homografts and patients' arteries, ensuring a reduced Γ and WΓ. Cryografts could be considered as alternatives in arterial reconstructions since they ensure the gradual transition of patients' arteries biomechanical and functional behavior. © 2008 Institute of Physiology v.v.i., Academy of Sciences of the Czech Republic. |
| format |
JOUR |
| author |
Santana Bia, D. Barra, J.G. Armentano, R.L. Zócalo, Y. Pérez, H. Saldías, M. Álvarez, I. Cabrera Fischer, E.I. |
| author_facet |
Santana Bia, D. Barra, J.G. Armentano, R.L. Zócalo, Y. Pérez, H. Saldías, M. Álvarez, I. Cabrera Fischer, E.I. |
| author_sort |
Santana Bia, D. |
| title |
Cryografts implantation in human circulation would ensure a physiological transition in the arterial wall energetics, damping and wave reflection |
| title_short |
Cryografts implantation in human circulation would ensure a physiological transition in the arterial wall energetics, damping and wave reflection |
| title_full |
Cryografts implantation in human circulation would ensure a physiological transition in the arterial wall energetics, damping and wave reflection |
| title_fullStr |
Cryografts implantation in human circulation would ensure a physiological transition in the arterial wall energetics, damping and wave reflection |
| title_full_unstemmed |
Cryografts implantation in human circulation would ensure a physiological transition in the arterial wall energetics, damping and wave reflection |
| title_sort |
cryografts implantation in human circulation would ensure a physiological transition in the arterial wall energetics, damping and wave reflection |
| url |
http://hdl.handle.net/20.500.12110/paper_08628408_v57_n3_p351_SantanaBia |
| work_keys_str_mv |
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