Chemiluminescence production by neutrophils and immune complex levels in cancer patients

We studied the production of chemiluminescence (CL) by peripheral blood neutrophils from 24 normal subjects, 13 lung cancer patients with clinical stages (CS) III and IV, and 27 breast cancer patients with CS II, III, and IV. Evaluations were made before chemo- and radiotherapy treatments. CL was ex...

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Autores principales:	Chasseing, N.A., Barañao, R.I., Fernández, O., Bordenave, H., Rumi, L.S.
Formato:	JOUR
Materias:	endogenous compound zymosan antigen antibody complex article breast cancer chemoluminescence clinical article controlled study female human human cell lung cancer male neutrophil Antigen-Antibody Complex Breast Neoplasms Chemiluminescence Human Lung Neoplasms Neutrophils Opsonins Oxygen Polyethylene Glycols Zymosan
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_07357907_v11_n5_p517_Chasseing
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

id	todo:paper_07357907_v11_n5_p517_Chasseing
record_format	dspace
spelling	todo:paper_07357907_v11_n5_p517_Chasseing2023-10-03T15:37:45Z Chemiluminescence production by neutrophils and immune complex levels in cancer patients Chasseing, N.A. Barañao, R.I. Fernández, O. Bordenave, H. Rumi, L.S. endogenous compound zymosan antigen antibody complex article breast cancer chemoluminescence clinical article controlled study female human human cell lung cancer male neutrophil Antigen-Antibody Complex Breast Neoplasms Chemiluminescence Human Lung Neoplasms Neutrophils Opsonins Oxygen Polyethylene Glycols Zymosan We studied the production of chemiluminescence (CL) by peripheral blood neutrophils from 24 normal subjects, 13 lung cancer patients with clinical stages (CS) III and IV, and 27 breast cancer patients with CS II, III, and IV. Evaluations were made before chemo- and radiotherapy treatments. CL was expressed as: baseline of the record background activity; area under the curve (AUC) of opsonized zymosan response; maximum peak (MP) response; time to MP (TMP); and total time (TT). Simultaneously, circulating immune complexes (CIC) in sera were evaluated by polyethylene glycol precipitation technique. The results demonstrated that lung cancer patients with CS III had an increase of TMP and TT values, while breast cancer patients with CS IV showed the lowest values of AUC and MP compared with the control group. The CIC levels were increased in all the cancer patients. There was no correlation between the baseline CL activity and the levels of immune complexes. © 1993 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_07357907_v11_n5_p517_Chasseing
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	endogenous compound zymosan antigen antibody complex article breast cancer chemoluminescence clinical article controlled study female human human cell lung cancer male neutrophil Antigen-Antibody Complex Breast Neoplasms Chemiluminescence Human Lung Neoplasms Neutrophils Opsonins Oxygen Polyethylene Glycols Zymosan
spellingShingle	endogenous compound zymosan antigen antibody complex article breast cancer chemoluminescence clinical article controlled study female human human cell lung cancer male neutrophil Antigen-Antibody Complex Breast Neoplasms Chemiluminescence Human Lung Neoplasms Neutrophils Opsonins Oxygen Polyethylene Glycols Zymosan Chasseing, N.A. Barañao, R.I. Fernández, O. Bordenave, H. Rumi, L.S. Chemiluminescence production by neutrophils and immune complex levels in cancer patients
topic_facet	endogenous compound zymosan antigen antibody complex article breast cancer chemoluminescence clinical article controlled study female human human cell lung cancer male neutrophil Antigen-Antibody Complex Breast Neoplasms Chemiluminescence Human Lung Neoplasms Neutrophils Opsonins Oxygen Polyethylene Glycols Zymosan
description	We studied the production of chemiluminescence (CL) by peripheral blood neutrophils from 24 normal subjects, 13 lung cancer patients with clinical stages (CS) III and IV, and 27 breast cancer patients with CS II, III, and IV. Evaluations were made before chemo- and radiotherapy treatments. CL was expressed as: baseline of the record background activity; area under the curve (AUC) of opsonized zymosan response; maximum peak (MP) response; time to MP (TMP); and total time (TT). Simultaneously, circulating immune complexes (CIC) in sera were evaluated by polyethylene glycol precipitation technique. The results demonstrated that lung cancer patients with CS III had an increase of TMP and TT values, while breast cancer patients with CS IV showed the lowest values of AUC and MP compared with the control group. The CIC levels were increased in all the cancer patients. There was no correlation between the baseline CL activity and the levels of immune complexes. © 1993 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.
format	JOUR
author	Chasseing, N.A. Barañao, R.I. Fernández, O. Bordenave, H. Rumi, L.S.
author_facet	Chasseing, N.A. Barañao, R.I. Fernández, O. Bordenave, H. Rumi, L.S.
author_sort	Chasseing, N.A.
title	Chemiluminescence production by neutrophils and immune complex levels in cancer patients
title_short	Chemiluminescence production by neutrophils and immune complex levels in cancer patients
title_full	Chemiluminescence production by neutrophils and immune complex levels in cancer patients
title_fullStr	Chemiluminescence production by neutrophils and immune complex levels in cancer patients
title_full_unstemmed	Chemiluminescence production by neutrophils and immune complex levels in cancer patients
title_sort	chemiluminescence production by neutrophils and immune complex levels in cancer patients
url	http://hdl.handle.net/20.500.12110/paper_07357907_v11_n5_p517_Chasseing
work_keys_str_mv	AT chasseingna chemiluminescenceproductionbyneutrophilsandimmunecomplexlevelsincancerpatients AT baranaori chemiluminescenceproductionbyneutrophilsandimmunecomplexlevelsincancerpatients AT fernandezo chemiluminescenceproductionbyneutrophilsandimmunecomplexlevelsincancerpatients AT bordenaveh chemiluminescenceproductionbyneutrophilsandimmunecomplexlevelsincancerpatients AT rumils chemiluminescenceproductionbyneutrophilsandimmunecomplexlevelsincancerpatients
_version_	1807315077546639360

Chemiluminescence production by neutrophils and immune complex levels in cancer patients

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