Antimicrobial constituents of Gomphrena martiana and Gomphrena boliviana

The antimicrobial activity of extracts and constituents of Gomphrena martiana and Gomphrena boliviana (Amaranthaceae) were determined in order to identify the compounds responsible for the folk-medicinal use of these plants. Each extract was evaluated against 20 microorganisms, including Gram-positi...

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Autores principales:	Pomilio, A.B., Buschi, C.A., Tomes, C.N., Viale, A.A.
Formato:	JOUR
Materias:	5,6,7-trisubstituted flavonoids Antimicrobial constituents Gomphrena boliviana Gomphrena martiana isorhamnetin 3-O-β-robinobioside flavonoid gomphrena boliviana extract gomphrena martiana extract isorhamnetin isorhamnetin 3 robinobioside plant extract unclassified drug antimicrobial activity article Aspergillus niger Bacillus subtilis bioassay Candida albicans chemical structure Clostridium butyricum Clostridium sporogenes Clostridium tetani Enterobacter aerogenes Enterococcus faecalis Escherichia coli fungus Gram negative bacterium Gram positive bacterium Klebsiella pneumoniae Micrococcus luteus Mycobacterium phlei nonhuman plant priority journal Proteus vulgaris Pseudomonas aeruginosa Saccharomyces cerevisiae Salmonella Serratia marcescens Staphylococcus aureus traditional medicine yeast Flavones Fungi Gram-Negative Bacteria Gram-Positive Bacteria Microbial Sensitivity Tests Plant Extracts Plants, Medicinal Support, Non-U.S. Gov't
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_03788741_v36_n2_p155_Pomilio
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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spelling	todo:paper_03788741_v36_n2_p155_Pomilio2023-10-03T15:33:19Z Antimicrobial constituents of Gomphrena martiana and Gomphrena boliviana Pomilio, A.B. Buschi, C.A. Tomes, C.N. Viale, A.A. 5,6,7-trisubstituted flavonoids Antimicrobial constituents Gomphrena boliviana Gomphrena martiana isorhamnetin 3-O-β-robinobioside flavonoid gomphrena boliviana extract gomphrena martiana extract isorhamnetin isorhamnetin 3 robinobioside plant extract unclassified drug antimicrobial activity article Aspergillus niger Bacillus subtilis bioassay Candida albicans chemical structure Clostridium butyricum Clostridium sporogenes Clostridium tetani Enterobacter aerogenes Enterococcus faecalis Escherichia coli fungus Gram negative bacterium Gram positive bacterium Klebsiella pneumoniae Micrococcus luteus Mycobacterium phlei nonhuman plant priority journal Proteus vulgaris Pseudomonas aeruginosa Saccharomyces cerevisiae Salmonella Serratia marcescens Staphylococcus aureus traditional medicine yeast Flavones Fungi Gram-Negative Bacteria Gram-Positive Bacteria Microbial Sensitivity Tests Plant Extracts Plants, Medicinal Support, Non-U.S. Gov't The antimicrobial activity of extracts and constituents of Gomphrena martiana and Gomphrena boliviana (Amaranthaceae) were determined in order to identify the compounds responsible for the folk-medicinal use of these plants. Each extract was evaluated against 20 microorganisms, including Gram-positive and Gram-negative bacteria, spore-forming Gram-positive bacteria, an acid-fast bacterium, a fungus and two yeasts. Fractionation of each petroleum ether (PE) extract yielded five 5,6,7-trisubstituted flavones that were separately tested showing high activity against M. phlei (minimum inhibitory concentration (MIC) 15, 20 and 75 μg ml) approaching that of commercial bactericides. Other natural and synthetic flavonoids with diverse structures were also tested to define structure-activity relationships. Each EtOH extract was subsequently fractionated and monitored by bioassays leading to isorhamnetin 3-O-β-robinobioside (MIC 50 μg/ml) in both instances. This glycoside is reported here for the first time in G. boliviana. © 1992. Fil:Pomilio, A.B. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Buschi, C.A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Tomes, C.N. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Viale, A.A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_03788741_v36_n2_p155_Pomilio
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	5,6,7-trisubstituted flavonoids Antimicrobial constituents Gomphrena boliviana Gomphrena martiana isorhamnetin 3-O-β-robinobioside flavonoid gomphrena boliviana extract gomphrena martiana extract isorhamnetin isorhamnetin 3 robinobioside plant extract unclassified drug antimicrobial activity article Aspergillus niger Bacillus subtilis bioassay Candida albicans chemical structure Clostridium butyricum Clostridium sporogenes Clostridium tetani Enterobacter aerogenes Enterococcus faecalis Escherichia coli fungus Gram negative bacterium Gram positive bacterium Klebsiella pneumoniae Micrococcus luteus Mycobacterium phlei nonhuman plant priority journal Proteus vulgaris Pseudomonas aeruginosa Saccharomyces cerevisiae Salmonella Serratia marcescens Staphylococcus aureus traditional medicine yeast Flavones Fungi Gram-Negative Bacteria Gram-Positive Bacteria Microbial Sensitivity Tests Plant Extracts Plants, Medicinal Support, Non-U.S. Gov't
spellingShingle	5,6,7-trisubstituted flavonoids Antimicrobial constituents Gomphrena boliviana Gomphrena martiana isorhamnetin 3-O-β-robinobioside flavonoid gomphrena boliviana extract gomphrena martiana extract isorhamnetin isorhamnetin 3 robinobioside plant extract unclassified drug antimicrobial activity article Aspergillus niger Bacillus subtilis bioassay Candida albicans chemical structure Clostridium butyricum Clostridium sporogenes Clostridium tetani Enterobacter aerogenes Enterococcus faecalis Escherichia coli fungus Gram negative bacterium Gram positive bacterium Klebsiella pneumoniae Micrococcus luteus Mycobacterium phlei nonhuman plant priority journal Proteus vulgaris Pseudomonas aeruginosa Saccharomyces cerevisiae Salmonella Serratia marcescens Staphylococcus aureus traditional medicine yeast Flavones Fungi Gram-Negative Bacteria Gram-Positive Bacteria Microbial Sensitivity Tests Plant Extracts Plants, Medicinal Support, Non-U.S. Gov't Pomilio, A.B. Buschi, C.A. Tomes, C.N. Viale, A.A. Antimicrobial constituents of Gomphrena martiana and Gomphrena boliviana
topic_facet	5,6,7-trisubstituted flavonoids Antimicrobial constituents Gomphrena boliviana Gomphrena martiana isorhamnetin 3-O-β-robinobioside flavonoid gomphrena boliviana extract gomphrena martiana extract isorhamnetin isorhamnetin 3 robinobioside plant extract unclassified drug antimicrobial activity article Aspergillus niger Bacillus subtilis bioassay Candida albicans chemical structure Clostridium butyricum Clostridium sporogenes Clostridium tetani Enterobacter aerogenes Enterococcus faecalis Escherichia coli fungus Gram negative bacterium Gram positive bacterium Klebsiella pneumoniae Micrococcus luteus Mycobacterium phlei nonhuman plant priority journal Proteus vulgaris Pseudomonas aeruginosa Saccharomyces cerevisiae Salmonella Serratia marcescens Staphylococcus aureus traditional medicine yeast Flavones Fungi Gram-Negative Bacteria Gram-Positive Bacteria Microbial Sensitivity Tests Plant Extracts Plants, Medicinal Support, Non-U.S. Gov't
description	The antimicrobial activity of extracts and constituents of Gomphrena martiana and Gomphrena boliviana (Amaranthaceae) were determined in order to identify the compounds responsible for the folk-medicinal use of these plants. Each extract was evaluated against 20 microorganisms, including Gram-positive and Gram-negative bacteria, spore-forming Gram-positive bacteria, an acid-fast bacterium, a fungus and two yeasts. Fractionation of each petroleum ether (PE) extract yielded five 5,6,7-trisubstituted flavones that were separately tested showing high activity against M. phlei (minimum inhibitory concentration (MIC) 15, 20 and 75 μg ml) approaching that of commercial bactericides. Other natural and synthetic flavonoids with diverse structures were also tested to define structure-activity relationships. Each EtOH extract was subsequently fractionated and monitored by bioassays leading to isorhamnetin 3-O-β-robinobioside (MIC 50 μg/ml) in both instances. This glycoside is reported here for the first time in G. boliviana. © 1992.
format	JOUR
author	Pomilio, A.B. Buschi, C.A. Tomes, C.N. Viale, A.A.
author_facet	Pomilio, A.B. Buschi, C.A. Tomes, C.N. Viale, A.A.
author_sort	Pomilio, A.B.
title	Antimicrobial constituents of Gomphrena martiana and Gomphrena boliviana
title_short	Antimicrobial constituents of Gomphrena martiana and Gomphrena boliviana
title_full	Antimicrobial constituents of Gomphrena martiana and Gomphrena boliviana
title_fullStr	Antimicrobial constituents of Gomphrena martiana and Gomphrena boliviana
title_full_unstemmed	Antimicrobial constituents of Gomphrena martiana and Gomphrena boliviana
title_sort	antimicrobial constituents of gomphrena martiana and gomphrena boliviana
url	http://hdl.handle.net/20.500.12110/paper_03788741_v36_n2_p155_Pomilio
work_keys_str_mv	AT pomilioab antimicrobialconstituentsofgomphrenamartianaandgomphrenaboliviana AT buschica antimicrobialconstituentsofgomphrenamartianaandgomphrenaboliviana AT tomescn antimicrobialconstituentsofgomphrenamartianaandgomphrenaboliviana AT vialeaa antimicrobialconstituentsofgomphrenamartianaandgomphrenaboliviana
_version_	1807322291020759040

Antimicrobial constituents of Gomphrena martiana and Gomphrena boliviana

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