A solution for non-constant mean open time in homogeneous Markov models

The InsP3 receptor is a ligand-gated calcium channel that is modulated both by InsP3 and Ca2+. Recent experiments have shown that the mean open time of the channel is not a monotonic function of [Ca+2]. In this work, we propose a solution for this type of behavior in a general framework. © 2003 Else...

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Detalles Bibliográficos
Autores principales: Fraiman, D., Dawson, S.P.
Formato: JOUR
Materias:
Ca+2
InsP3
Mean open time
Subconductances
Calcium
Positive ions
Proteins
Calcium channels
Markov processes
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_03784371_v327_n1-2_p162_Fraiman
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
id todo:paper_03784371_v327_n1-2_p162_Fraiman
record_format dspace
spelling todo:paper_03784371_v327_n1-2_p162_Fraiman2023-10-03T15:32:39Z A solution for non-constant mean open time in homogeneous Markov models Fraiman, D. Dawson, S.P. Ca+2 InsP3 Mean open time Subconductances Calcium Positive ions Proteins Calcium channels Markov processes The InsP3 receptor is a ligand-gated calcium channel that is modulated both by InsP3 and Ca2+. Recent experiments have shown that the mean open time of the channel is not a monotonic function of [Ca+2]. In this work, we propose a solution for this type of behavior in a general framework. © 2003 Elsevier B.V. All rights reserved. Fil:Dawson, S.P. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_03784371_v327_n1-2_p162_Fraiman
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic Ca+2
InsP3
Mean open time
Subconductances
Calcium
Positive ions
Proteins
Calcium channels
Markov processes
spellingShingle Ca+2
InsP3
Mean open time
Subconductances
Calcium
Positive ions
Proteins
Calcium channels
Markov processes
Fraiman, D.
Dawson, S.P.
A solution for non-constant mean open time in homogeneous Markov models
topic_facet Ca+2
InsP3
Mean open time
Subconductances
Calcium
Positive ions
Proteins
Calcium channels
Markov processes
description The InsP3 receptor is a ligand-gated calcium channel that is modulated both by InsP3 and Ca2+. Recent experiments have shown that the mean open time of the channel is not a monotonic function of [Ca+2]. In this work, we propose a solution for this type of behavior in a general framework. © 2003 Elsevier B.V. All rights reserved.
format JOUR
author Fraiman, D.
Dawson, S.P.
author_facet Fraiman, D.
Dawson, S.P.
author_sort Fraiman, D.
title A solution for non-constant mean open time in homogeneous Markov models
title_short A solution for non-constant mean open time in homogeneous Markov models
title_full A solution for non-constant mean open time in homogeneous Markov models
title_fullStr A solution for non-constant mean open time in homogeneous Markov models
title_full_unstemmed A solution for non-constant mean open time in homogeneous Markov models
title_sort solution for non-constant mean open time in homogeneous markov models
url http://hdl.handle.net/20.500.12110/paper_03784371_v327_n1-2_p162_Fraiman
work_keys_str_mv AT fraimand asolutionfornonconstantmeanopentimeinhomogeneousmarkovmodels
AT dawsonsp asolutionfornonconstantmeanopentimeinhomogeneousmarkovmodels
AT fraimand solutionfornonconstantmeanopentimeinhomogeneousmarkovmodels
AT dawsonsp solutionfornonconstantmeanopentimeinhomogeneousmarkovmodels
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