Myosin light chain kinase inhibitors induce retraction of mature oligodendrocyte processes

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Mature oligodendrocytes emit numerous myelinating processes. Force generating molecules are required for process outgrowth and spreading. We have analyzed the effect of the myosin II light chain kinase inhibitors ML-7 and ML-9 in cultured oligodendrocytes. Both drugs affect oligo-dendrocyte cell sha...

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Detalles Bibliográficos
Autores principales: Thomas, M.G., Santa Coloma, T.A., Correale, J., Boccaccio, G.L.
Formato: JOUR
Materias:
ML-7
ML-9
MLCK
Myelin
Myosin II
Oligodendrocyte processes
myosin IIA
myosin light chain kinase inhibitor
protein ml 7
protein ml 9
unclassified drug
animal tissue
article
cell activity
cell adhesion
cell culture
cell differentiation
cell growth
cell maturation
cell shape
central nervous system
controlled study
immunohistochemistry
myelination
nonhuman
oligodendroglia
phosphorylation
priority journal
rat
Animals
Azepines
Enzyme Inhibitors
Myosin-Light-Chain Kinase
Naphthalenes
Oligodendroglia
Phosphorylation
Rats
Rats, Wistar
Animalia
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_03643190_v27_n11_p1305_Thomas
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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