Synthesis of [131-I]-iodinated quercetin
Two iodination procedures via thallation were applied to quercetin leading to the formation of 2'-iodoquercetin and 2',6,8-triiodoquercetin; their structures being elucidated by FT-IR and NMR spectral analysis. The preparation of mono- and polyiodinated products is discussed here on the ba...
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| Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_03624803_v39_n11_p927_Barolli |
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todo:paper_03624803_v39_n11_p927_Barolli2023-10-03T15:27:08Z Synthesis of [131-I]-iodinated quercetin Barolli, M.G. Pomilio, A.B. 131-iodine 2',6,8- triiodoquercetin 2'-iodoquercetin Iodination Quercetin Radiolabelling iodine 131 quercetin antioxidant activity article drug structure drug synthesis iodination oxidative stress Two iodination procedures via thallation were applied to quercetin leading to the formation of 2'-iodoquercetin and 2',6,8-triiodoquercetin; their structures being elucidated by FT-IR and NMR spectral analysis. The preparation of mono- and polyiodinated products is discussed here on the basis of the experimental details and spectral data. This is the first report on the radiolabelling of quercetin, which is here selectively performed with 131-iodine. The radiochemical purity was of 99%. Fil:Pomilio, A.B. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_03624803_v39_n11_p927_Barolli |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
131-iodine 2',6,8- triiodoquercetin 2'-iodoquercetin Iodination Quercetin Radiolabelling iodine 131 quercetin antioxidant activity article drug structure drug synthesis iodination oxidative stress |
| spellingShingle |
131-iodine 2',6,8- triiodoquercetin 2'-iodoquercetin Iodination Quercetin Radiolabelling iodine 131 quercetin antioxidant activity article drug structure drug synthesis iodination oxidative stress Barolli, M.G. Pomilio, A.B. Synthesis of [131-I]-iodinated quercetin |
| topic_facet |
131-iodine 2',6,8- triiodoquercetin 2'-iodoquercetin Iodination Quercetin Radiolabelling iodine 131 quercetin antioxidant activity article drug structure drug synthesis iodination oxidative stress |
| description |
Two iodination procedures via thallation were applied to quercetin leading to the formation of 2'-iodoquercetin and 2',6,8-triiodoquercetin; their structures being elucidated by FT-IR and NMR spectral analysis. The preparation of mono- and polyiodinated products is discussed here on the basis of the experimental details and spectral data. This is the first report on the radiolabelling of quercetin, which is here selectively performed with 131-iodine. The radiochemical purity was of 99%. |
| format |
JOUR |
| author |
Barolli, M.G. Pomilio, A.B. |
| author_facet |
Barolli, M.G. Pomilio, A.B. |
| author_sort |
Barolli, M.G. |
| title |
Synthesis of [131-I]-iodinated quercetin |
| title_short |
Synthesis of [131-I]-iodinated quercetin |
| title_full |
Synthesis of [131-I]-iodinated quercetin |
| title_fullStr |
Synthesis of [131-I]-iodinated quercetin |
| title_full_unstemmed |
Synthesis of [131-I]-iodinated quercetin |
| title_sort |
synthesis of [131-i]-iodinated quercetin |
| url |
http://hdl.handle.net/20.500.12110/paper_03624803_v39_n11_p927_Barolli |
| work_keys_str_mv |
AT barollimg synthesisof131iiodinatedquercetin AT pomilioab synthesisof131iiodinatedquercetin |
| _version_ |
1807318752159596544 |