Synthesis of |21‐14C|‐3β‐hydroxy‐5β‐pregnan‐20‐one and |21‐14C|‐5β‐cholestan‐3β‐ol

|21‐14C|‐3β‐Hydroxy‐5β‐pregnan‐20‐one was synthesised from 3β‐acetoxy‐5β‐androstan‐17β‐carboxylic acid chloride and |14C2|dimethyl‐cadmium. Reaction of the labelled product with isohexyl bromide yielded, after dehydration and catalytic hydrogenation, |21‐14C|‐5β‐cholestan‐3β‐ol (|21‐14C|‐coprostanol...

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Autores principales:	Garraffo, H.M., Deluca, M.E., Seldes, A.M., Gross, E.G.
Formato:	JOUR
Materias:	Synthesis \|21‐14C\|‐3β‐Hydroxy‐5β‐pregnan‐20‐one \|21‐14C\|‐Coprostanol radioisotope 5beta pregnan 3beta ol 20 one c 14 coprosterol c 14 drug analysis drug identification drug synthesis mass spectrometry nonhuman nuclear magnetic resonance priority journal proton nuclear magnetic resonance theoretical study
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_03624803_v22_n7_p673_Garraffo
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

id	todo:paper_03624803_v22_n7_p673_Garraffo
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spelling	todo:paper_03624803_v22_n7_p673_Garraffo2023-10-03T15:27:04Z Synthesis of \|21‐14C\|‐3β‐hydroxy‐5β‐pregnan‐20‐one and \|21‐14C\|‐5β‐cholestan‐3β‐ol Garraffo, H.M. Deluca, M.E. Seldes, A.M. Gross, E.G. Synthesis \|21‐14C\|‐3β‐Hydroxy‐5β‐pregnan‐20‐one \|21‐14C\|‐Coprostanol radioisotope 5beta pregnan 3beta ol 20 one c 14 coprosterol c 14 drug analysis drug identification drug synthesis mass spectrometry nonhuman nuclear magnetic resonance priority journal proton nuclear magnetic resonance theoretical study \|21‐14C\|‐3β‐Hydroxy‐5β‐pregnan‐20‐one was synthesised from 3β‐acetoxy‐5β‐androstan‐17β‐carboxylic acid chloride and \|14C2\|dimethyl‐cadmium. Reaction of the labelled product with isohexyl bromide yielded, after dehydration and catalytic hydrogenation, \|21‐14C\|‐5β‐cholestan‐3β‐ol (\|21‐14C\|‐coprostanol). Copyright © 1985 John Wiley & Sons, Ltd. Fil:Garraffo, H.M. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Deluca, M.E. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Seldes, A.M. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_03624803_v22_n7_p673_Garraffo
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	Synthesis \|21‐14C\|‐3β‐Hydroxy‐5β‐pregnan‐20‐one \|21‐14C\|‐Coprostanol radioisotope 5beta pregnan 3beta ol 20 one c 14 coprosterol c 14 drug analysis drug identification drug synthesis mass spectrometry nonhuman nuclear magnetic resonance priority journal proton nuclear magnetic resonance theoretical study
spellingShingle	Synthesis \|21‐14C\|‐3β‐Hydroxy‐5β‐pregnan‐20‐one \|21‐14C\|‐Coprostanol radioisotope 5beta pregnan 3beta ol 20 one c 14 coprosterol c 14 drug analysis drug identification drug synthesis mass spectrometry nonhuman nuclear magnetic resonance priority journal proton nuclear magnetic resonance theoretical study Garraffo, H.M. Deluca, M.E. Seldes, A.M. Gross, E.G. Synthesis of \|21‐14C\|‐3β‐hydroxy‐5β‐pregnan‐20‐one and \|21‐14C\|‐5β‐cholestan‐3β‐ol
topic_facet	Synthesis \|21‐14C\|‐3β‐Hydroxy‐5β‐pregnan‐20‐one \|21‐14C\|‐Coprostanol radioisotope 5beta pregnan 3beta ol 20 one c 14 coprosterol c 14 drug analysis drug identification drug synthesis mass spectrometry nonhuman nuclear magnetic resonance priority journal proton nuclear magnetic resonance theoretical study
description	\|21‐14C\|‐3β‐Hydroxy‐5β‐pregnan‐20‐one was synthesised from 3β‐acetoxy‐5β‐androstan‐17β‐carboxylic acid chloride and \|14C2\|dimethyl‐cadmium. Reaction of the labelled product with isohexyl bromide yielded, after dehydration and catalytic hydrogenation, \|21‐14C\|‐5β‐cholestan‐3β‐ol (\|21‐14C\|‐coprostanol). Copyright © 1985 John Wiley & Sons, Ltd.
format	JOUR
author	Garraffo, H.M. Deluca, M.E. Seldes, A.M. Gross, E.G.
author_facet	Garraffo, H.M. Deluca, M.E. Seldes, A.M. Gross, E.G.
author_sort	Garraffo, H.M.
title	Synthesis of \|21‐14C\|‐3β‐hydroxy‐5β‐pregnan‐20‐one and \|21‐14C\|‐5β‐cholestan‐3β‐ol
title_short	Synthesis of \|21‐14C\|‐3β‐hydroxy‐5β‐pregnan‐20‐one and \|21‐14C\|‐5β‐cholestan‐3β‐ol
title_full	Synthesis of \|21‐14C\|‐3β‐hydroxy‐5β‐pregnan‐20‐one and \|21‐14C\|‐5β‐cholestan‐3β‐ol
title_fullStr	Synthesis of \|21‐14C\|‐3β‐hydroxy‐5β‐pregnan‐20‐one and \|21‐14C\|‐5β‐cholestan‐3β‐ol
title_full_unstemmed	Synthesis of \|21‐14C\|‐3β‐hydroxy‐5β‐pregnan‐20‐one and \|21‐14C\|‐5β‐cholestan‐3β‐ol
title_sort	synthesis of \|21‐14c\|‐3β‐hydroxy‐5β‐pregnan‐20‐one and \|21‐14c\|‐5β‐cholestan‐3β‐ol
url	http://hdl.handle.net/20.500.12110/paper_03624803_v22_n7_p673_Garraffo
work_keys_str_mv	AT garraffohm synthesisof2114c3bhydroxy5bpregnan20oneand2114c5bcholestan3bol AT delucame synthesisof2114c3bhydroxy5bpregnan20oneand2114c5bcholestan3bol AT seldesam synthesisof2114c3bhydroxy5bpregnan20oneand2114c5bcholestan3bol AT grosseg synthesisof2114c3bhydroxy5bpregnan20oneand2114c5bcholestan3bol
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Synthesis of |21‐14C|‐3β‐hydroxy‐5β‐pregnan‐20‐one and |21‐14C|‐5β‐cholestan‐3β‐ol

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