Processing of sensory signals by a non-spiking neuron in the leech

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The non-spiking neurons 151 are present as bilateral pairs in each midbody ganglion of the leech nervous system and they are electrically coupled to several motorneurons. Intracellular recordings were used to investigate how these neurons process input from the mechanosensory P neurons in isolated g...

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Autores principales: Marín-Burgin, A., Szczupak, L.
Formato: JOUR
Materias:
Leech
Mechanosensory
Non-spiking
Sensory processing
Strychnine
poison
strychnine
action potential
animal
article
cytology
drug effect
electrophysiology
ganglion
interneuron
leech
mechanoreceptor
movement (physiology)
physiology
sensory nerve cell
synapse
Action Potentials
Animals
Electrophysiology
Ganglia, Invertebrate
Interneurons
Leeches
Mechanoreceptors
Movement
Neurons, Afferent
Poisons
Synapses
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_03407594_v186_n10_p989_MarinBurgin
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
id todo:paper_03407594_v186_n10_p989_MarinBurgin
record_format dspace
spelling todo:paper_03407594_v186_n10_p989_MarinBurgin2023-10-03T15:25:56Z Processing of sensory signals by a non-spiking neuron in the leech Marín-Burgin, A. Szczupak, L. Leech Mechanosensory Non-spiking Sensory processing Strychnine poison strychnine action potential animal article cytology drug effect electrophysiology ganglion interneuron leech mechanoreceptor movement (physiology) physiology sensory nerve cell synapse Action Potentials Animals Electrophysiology Ganglia, Invertebrate Interneurons Leeches Mechanoreceptors Movement Neurons, Afferent Poisons Strychnine Synapses The non-spiking neurons 151 are present as bilateral pairs in each midbody ganglion of the leech nervous system and they are electrically coupled to several motorneurons. Intracellular recordings were used to investigate how these neurons process input from the mechanosensory P neurons in isolated ganglia. Induction of spike trains (15 Hz) in single P cells evoked responses that combined depolarizing and hyperpolarizing phases in cells 151. The phasic depolarizations, transmitted through spiking interneurons, reversed at around -20 mV. The hyperpolarization had two components, both reversing at around -65 mV, and which were inhibited by strychnine (10 μmol l-1). The faster component was transmitted through spiking interneurons and the slower component through a direct P-151 interaction. Short trains (< 400 ms) of P cell spikes (15 Hz) evoked the phasic depolarizations superimposed on the hyperpolarization, while long spike trains (> 500 ms) produced a succession of depolarizations that masked the hyperpolarizing phase. The amplitude and duration of the hyperpolarization reached their maximum at the initial spikes in a train, while the depolarizations persisted throughout the duration of the stimulus train. Both phases of the response were relatively unaffected by the spike frequency (5-25 Hz). The non-spiking neurons 151 processed the sensory signals in the temporal rather than in the amplitude domain. Fil:Marín-Burgin, A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Szczupak, L. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_03407594_v186_n10_p989_MarinBurgin
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic Leech
Mechanosensory
Non-spiking
Sensory processing
Strychnine
poison
strychnine
action potential
animal
article
cytology
drug effect
electrophysiology
ganglion
interneuron
leech
mechanoreceptor
movement (physiology)
physiology
sensory nerve cell
synapse
Action Potentials
Animals
Electrophysiology
Ganglia, Invertebrate
Interneurons
Leeches
Mechanoreceptors
Movement
Neurons, Afferent
Poisons
Strychnine
Synapses
spellingShingle Leech
Mechanosensory
Non-spiking
Sensory processing
Strychnine
poison
strychnine
action potential
animal
article
cytology
drug effect
electrophysiology
ganglion
interneuron
leech
mechanoreceptor
movement (physiology)
physiology
sensory nerve cell
synapse
Action Potentials
Animals
Electrophysiology
Ganglia, Invertebrate
Interneurons
Leeches
Mechanoreceptors
Movement
Neurons, Afferent
Poisons
Strychnine
Synapses
Marín-Burgin, A.
Szczupak, L.
Processing of sensory signals by a non-spiking neuron in the leech
topic_facet Leech
Mechanosensory
Non-spiking
Sensory processing
Strychnine
poison
strychnine
action potential
animal
article
cytology
drug effect
electrophysiology
ganglion
interneuron
leech
mechanoreceptor
movement (physiology)
physiology
sensory nerve cell
synapse
Action Potentials
Animals
Electrophysiology
Ganglia, Invertebrate
Interneurons
Leeches
Mechanoreceptors
Movement
Neurons, Afferent
Poisons
Strychnine
Synapses
description The non-spiking neurons 151 are present as bilateral pairs in each midbody ganglion of the leech nervous system and they are electrically coupled to several motorneurons. Intracellular recordings were used to investigate how these neurons process input from the mechanosensory P neurons in isolated ganglia. Induction of spike trains (15 Hz) in single P cells evoked responses that combined depolarizing and hyperpolarizing phases in cells 151. The phasic depolarizations, transmitted through spiking interneurons, reversed at around -20 mV. The hyperpolarization had two components, both reversing at around -65 mV, and which were inhibited by strychnine (10 μmol l-1). The faster component was transmitted through spiking interneurons and the slower component through a direct P-151 interaction. Short trains (< 400 ms) of P cell spikes (15 Hz) evoked the phasic depolarizations superimposed on the hyperpolarization, while long spike trains (> 500 ms) produced a succession of depolarizations that masked the hyperpolarizing phase. The amplitude and duration of the hyperpolarization reached their maximum at the initial spikes in a train, while the depolarizations persisted throughout the duration of the stimulus train. Both phases of the response were relatively unaffected by the spike frequency (5-25 Hz). The non-spiking neurons 151 processed the sensory signals in the temporal rather than in the amplitude domain.
format JOUR
author Marín-Burgin, A.
Szczupak, L.
author_facet Marín-Burgin, A.
Szczupak, L.
author_sort Marín-Burgin, A.
title Processing of sensory signals by a non-spiking neuron in the leech
title_short Processing of sensory signals by a non-spiking neuron in the leech
title_full Processing of sensory signals by a non-spiking neuron in the leech
title_fullStr Processing of sensory signals by a non-spiking neuron in the leech
title_full_unstemmed Processing of sensory signals by a non-spiking neuron in the leech
title_sort processing of sensory signals by a non-spiking neuron in the leech
url http://hdl.handle.net/20.500.12110/paper_03407594_v186_n10_p989_MarinBurgin
work_keys_str_mv AT marinburgina processingofsensorysignalsbyanonspikingneuronintheleech
AT szczupakl processingofsensorysignalsbyanonspikingneuronintheleech
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