Characterization of the mechanic behavior of the conduits used in the confection of vascular accesses in dialyzed subjects
Intimal hyperplasia development is recognized as the most important cause of vascular access failure in patients submitted renal function replacement therapy. An important factor that affects the development of intimal hyperplasia is elastic mismatch between native vessel and among vein, arteries an...
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| Formato: | JOUR |
| Lenguaje: | Spanish |
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| Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_03263428_v25_n4_p141_Zocalo |
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todo:paper_03263428_v25_n4_p141_Zocalo2023-10-03T15:24:32Z Characterization of the mechanic behavior of the conduits used in the confection of vascular accesses in dialyzed subjects Zócalo, Y. Pérez Campos, H. Galli, C.N. Saldías, M. Camus, J.M. Silva, W. Bia Santana, D. Álvarez, O. Álvarez, I. Armentano, R. politef arterial pressure artery diameter article biomechanics blood vessel compliance blood vessel parameters controlled study cryopreservation elasticity hemodialysis hemodialysis patient human human tissue in vitro study pneumatic tool politef implant treatment outcome ultrasound vascular access vein diameter venous pressure Intimal hyperplasia development is recognized as the most important cause of vascular access failure in patients submitted renal function replacement therapy. An important factor that affects the development of intimal hyperplasia is elastic mismatch between native vessel and among vein, arteries and the synthetic graft. In this work, a biomechanical analysis of cryopreserved arteries, expanded polytetrafluoroethylene (ePTFE), and fresh arteries and veins is reported. In vitro pressure (Konigsberg) and diameter (Sonomicrometry) were measured in fresh human vein and arteries and cryopreserved human defrosted arteries and ePTFE prosthesis, under isobaric and systemic pressures levels. Our results showed that ePTFE conduits have an elastic index which is significantly different from that of fresh and cryopreserved defrosted arteries and veins. These stiffness differences determine a high elastic mismatch. We conclude that this study of tubular segments to be used as vascular accesses in dialyzed patients, demonstrate significantly elastic differences that could be an important determinant of late access viability. JOUR Spanish info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_03263428_v25_n4_p141_Zocalo |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| language |
Spanish |
| orig_language_str_mv |
Spanish |
| topic |
politef arterial pressure artery diameter article biomechanics blood vessel compliance blood vessel parameters controlled study cryopreservation elasticity hemodialysis hemodialysis patient human human tissue in vitro study pneumatic tool politef implant treatment outcome ultrasound vascular access vein diameter venous pressure |
| spellingShingle |
politef arterial pressure artery diameter article biomechanics blood vessel compliance blood vessel parameters controlled study cryopreservation elasticity hemodialysis hemodialysis patient human human tissue in vitro study pneumatic tool politef implant treatment outcome ultrasound vascular access vein diameter venous pressure Zócalo, Y. Pérez Campos, H. Galli, C.N. Saldías, M. Camus, J.M. Silva, W. Bia Santana, D. Álvarez, O. Álvarez, I. Armentano, R. Characterization of the mechanic behavior of the conduits used in the confection of vascular accesses in dialyzed subjects |
| topic_facet |
politef arterial pressure artery diameter article biomechanics blood vessel compliance blood vessel parameters controlled study cryopreservation elasticity hemodialysis hemodialysis patient human human tissue in vitro study pneumatic tool politef implant treatment outcome ultrasound vascular access vein diameter venous pressure |
| description |
Intimal hyperplasia development is recognized as the most important cause of vascular access failure in patients submitted renal function replacement therapy. An important factor that affects the development of intimal hyperplasia is elastic mismatch between native vessel and among vein, arteries and the synthetic graft. In this work, a biomechanical analysis of cryopreserved arteries, expanded polytetrafluoroethylene (ePTFE), and fresh arteries and veins is reported. In vitro pressure (Konigsberg) and diameter (Sonomicrometry) were measured in fresh human vein and arteries and cryopreserved human defrosted arteries and ePTFE prosthesis, under isobaric and systemic pressures levels. Our results showed that ePTFE conduits have an elastic index which is significantly different from that of fresh and cryopreserved defrosted arteries and veins. These stiffness differences determine a high elastic mismatch. We conclude that this study of tubular segments to be used as vascular accesses in dialyzed patients, demonstrate significantly elastic differences that could be an important determinant of late access viability. |
| format |
JOUR |
| author |
Zócalo, Y. Pérez Campos, H. Galli, C.N. Saldías, M. Camus, J.M. Silva, W. Bia Santana, D. Álvarez, O. Álvarez, I. Armentano, R. |
| author_facet |
Zócalo, Y. Pérez Campos, H. Galli, C.N. Saldías, M. Camus, J.M. Silva, W. Bia Santana, D. Álvarez, O. Álvarez, I. Armentano, R. |
| author_sort |
Zócalo, Y. |
| title |
Characterization of the mechanic behavior of the conduits used in the confection of vascular accesses in dialyzed subjects |
| title_short |
Characterization of the mechanic behavior of the conduits used in the confection of vascular accesses in dialyzed subjects |
| title_full |
Characterization of the mechanic behavior of the conduits used in the confection of vascular accesses in dialyzed subjects |
| title_fullStr |
Characterization of the mechanic behavior of the conduits used in the confection of vascular accesses in dialyzed subjects |
| title_full_unstemmed |
Characterization of the mechanic behavior of the conduits used in the confection of vascular accesses in dialyzed subjects |
| title_sort |
characterization of the mechanic behavior of the conduits used in the confection of vascular accesses in dialyzed subjects |
| url |
http://hdl.handle.net/20.500.12110/paper_03263428_v25_n4_p141_Zocalo |
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