Rhodanese and ALA-S in mammary tumor and liver from normal and tumor-bearing mice
1. 1. Basal levels and allyl-isopropylacetamide (AIA) or veronal induced levels of δ-amino-levulinate synthetase (ALA-S), cytoplasmic and mitochondrial rhodanese were determined in tumor (T) and liver of both normal mice (NM) and T-bearing mice (TBM). 2. 2. Rhodanese tumoral mitochondrial levels wer...
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todo:paper_03050491_v102_n1_p83_Navone2023-10-03T15:21:12Z Rhodanese and ALA-S in mammary tumor and liver from normal and tumor-bearing mice Navone, N.M. Vázquez, E.S. Polo, C.F. del C. Batlle, A.M. thiosulfate sulfurtransferase animal experiment article breast tumor liver mitochondrion mouse nonhuman priority journal 5-Aminolevulinate Synthetase Allylisopropylacetamide Animal Barbital Cytoplasm Enzyme Induction Liver Male Mammary Neoplasms, Experimental Mice Mice, Inbred BALB C Mitochondria Support, Non-U.S. Gov't Thiosulfate Sulfurtransferase Animalia 1. 1. Basal levels and allyl-isopropylacetamide (AIA) or veronal induced levels of δ-amino-levulinate synthetase (ALA-S), cytoplasmic and mitochondrial rhodanese were determined in tumor (T) and liver of both normal mice (NM) and T-bearing mice (TBM). 2. 2. Rhodanese tumoral mitochondrial levels were higher than the hepatic normal mitochondrial fraction, while the cytoplasmic activity was nearly equal in all sources. 3. 3. In neither case was the activity of tumoral ALA-S and rhodanese altered by any of the porphyrinogenic drugs. 4. 4. Mitochondrial and cytoplasmic rhodanese activity was also measured in tumor and liver of TBM at different intervals after transplantation. We concluded that the behaviour of rhodanese is a property inherent to the tissue and not one attained with time. © 1992. Fil:Vázquez, E.S. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:del C. Batlle, A.M. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_03050491_v102_n1_p83_Navone |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
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R-134 |
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Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
thiosulfate sulfurtransferase animal experiment article breast tumor liver mitochondrion mouse nonhuman priority journal 5-Aminolevulinate Synthetase Allylisopropylacetamide Animal Barbital Cytoplasm Enzyme Induction Liver Male Mammary Neoplasms, Experimental Mice Mice, Inbred BALB C Mitochondria Support, Non-U.S. Gov't Thiosulfate Sulfurtransferase Animalia |
| spellingShingle |
thiosulfate sulfurtransferase animal experiment article breast tumor liver mitochondrion mouse nonhuman priority journal 5-Aminolevulinate Synthetase Allylisopropylacetamide Animal Barbital Cytoplasm Enzyme Induction Liver Male Mammary Neoplasms, Experimental Mice Mice, Inbred BALB C Mitochondria Support, Non-U.S. Gov't Thiosulfate Sulfurtransferase Animalia Navone, N.M. Vázquez, E.S. Polo, C.F. del C. Batlle, A.M. Rhodanese and ALA-S in mammary tumor and liver from normal and tumor-bearing mice |
| topic_facet |
thiosulfate sulfurtransferase animal experiment article breast tumor liver mitochondrion mouse nonhuman priority journal 5-Aminolevulinate Synthetase Allylisopropylacetamide Animal Barbital Cytoplasm Enzyme Induction Liver Male Mammary Neoplasms, Experimental Mice Mice, Inbred BALB C Mitochondria Support, Non-U.S. Gov't Thiosulfate Sulfurtransferase Animalia |
| description |
1. 1. Basal levels and allyl-isopropylacetamide (AIA) or veronal induced levels of δ-amino-levulinate synthetase (ALA-S), cytoplasmic and mitochondrial rhodanese were determined in tumor (T) and liver of both normal mice (NM) and T-bearing mice (TBM). 2. 2. Rhodanese tumoral mitochondrial levels were higher than the hepatic normal mitochondrial fraction, while the cytoplasmic activity was nearly equal in all sources. 3. 3. In neither case was the activity of tumoral ALA-S and rhodanese altered by any of the porphyrinogenic drugs. 4. 4. Mitochondrial and cytoplasmic rhodanese activity was also measured in tumor and liver of TBM at different intervals after transplantation. We concluded that the behaviour of rhodanese is a property inherent to the tissue and not one attained with time. © 1992. |
| format |
JOUR |
| author |
Navone, N.M. Vázquez, E.S. Polo, C.F. del C. Batlle, A.M. |
| author_facet |
Navone, N.M. Vázquez, E.S. Polo, C.F. del C. Batlle, A.M. |
| author_sort |
Navone, N.M. |
| title |
Rhodanese and ALA-S in mammary tumor and liver from normal and tumor-bearing mice |
| title_short |
Rhodanese and ALA-S in mammary tumor and liver from normal and tumor-bearing mice |
| title_full |
Rhodanese and ALA-S in mammary tumor and liver from normal and tumor-bearing mice |
| title_fullStr |
Rhodanese and ALA-S in mammary tumor and liver from normal and tumor-bearing mice |
| title_full_unstemmed |
Rhodanese and ALA-S in mammary tumor and liver from normal and tumor-bearing mice |
| title_sort |
rhodanese and ala-s in mammary tumor and liver from normal and tumor-bearing mice |
| url |
http://hdl.handle.net/20.500.12110/paper_03050491_v102_n1_p83_Navone |
| work_keys_str_mv |
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1782026072358912000 |