A mouse attenuated mutant of Junin virus with an altered envelope glycoprotein

The XJCl3 strain of Junin virus (JV) and the mouse-attenuated mutant Cl67 showed different GP 38 peptide mapping after limited proteolysis with ficin and papain; viral infectivity of both viruses also exhibited a different susceptibility to protease treatment. A correlation between envelope glycopro...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Scolaro, L.A., Mersich, S.E., Damonte, E.B.
Formato: JOUR
Materias:
virus envelope protein
virus glycoprotein
article
junin virus
nonhuman
virus attenuation
Animal
Arenaviridae
Arenaviruses, New World
Electrophoresis, Polyacrylamide Gel
Glycoproteins
Mice
Mutation
Peptide Mapping
Support, Non-U.S. Gov't
Viral Envelope Proteins
Virus Replication
Junin virus
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_03048608_v111_n3-4_p257_Scolaro
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
id todo:paper_03048608_v111_n3-4_p257_Scolaro
record_format dspace
spelling todo:paper_03048608_v111_n3-4_p257_Scolaro2023-10-03T15:20:55Z A mouse attenuated mutant of Junin virus with an altered envelope glycoprotein Scolaro, L.A. Mersich, S.E. Damonte, E.B. virus envelope protein virus glycoprotein article junin virus nonhuman virus attenuation Animal Arenaviridae Arenaviruses, New World Electrophoresis, Polyacrylamide Gel Glycoproteins Mice Mutation Peptide Mapping Support, Non-U.S. Gov't Viral Envelope Proteins Virus Replication Junin virus The XJCl3 strain of Junin virus (JV) and the mouse-attenuated mutant Cl67 showed different GP 38 peptide mapping after limited proteolysis with ficin and papain; viral infectivity of both viruses also exhibited a different susceptibility to protease treatment. A correlation between envelope glycoprotein alteration and JV virulence in neonatal mice is proposed. © 1990 Springer-Verlag. Fil:Scolaro, L.A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Mersich, S.E. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Damonte, E.B. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_03048608_v111_n3-4_p257_Scolaro
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic virus envelope protein
virus glycoprotein
article
junin virus
nonhuman
virus attenuation
Animal
Arenaviridae
Arenaviruses, New World
Electrophoresis, Polyacrylamide Gel
Glycoproteins
Mice
Mutation
Peptide Mapping
Support, Non-U.S. Gov't
Viral Envelope Proteins
Virus Replication
Junin virus
spellingShingle virus envelope protein
virus glycoprotein
article
junin virus
nonhuman
virus attenuation
Animal
Arenaviridae
Arenaviruses, New World
Electrophoresis, Polyacrylamide Gel
Glycoproteins
Mice
Mutation
Peptide Mapping
Support, Non-U.S. Gov't
Viral Envelope Proteins
Virus Replication
Junin virus
Scolaro, L.A.
Mersich, S.E.
Damonte, E.B.
A mouse attenuated mutant of Junin virus with an altered envelope glycoprotein
topic_facet virus envelope protein
virus glycoprotein
article
junin virus
nonhuman
virus attenuation
Animal
Arenaviridae
Arenaviruses, New World
Electrophoresis, Polyacrylamide Gel
Glycoproteins
Mice
Mutation
Peptide Mapping
Support, Non-U.S. Gov't
Viral Envelope Proteins
Virus Replication
Junin virus
description The XJCl3 strain of Junin virus (JV) and the mouse-attenuated mutant Cl67 showed different GP 38 peptide mapping after limited proteolysis with ficin and papain; viral infectivity of both viruses also exhibited a different susceptibility to protease treatment. A correlation between envelope glycoprotein alteration and JV virulence in neonatal mice is proposed. © 1990 Springer-Verlag.
format JOUR
author Scolaro, L.A.
Mersich, S.E.
Damonte, E.B.
author_facet Scolaro, L.A.
Mersich, S.E.
Damonte, E.B.
author_sort Scolaro, L.A.
title A mouse attenuated mutant of Junin virus with an altered envelope glycoprotein
title_short A mouse attenuated mutant of Junin virus with an altered envelope glycoprotein
title_full A mouse attenuated mutant of Junin virus with an altered envelope glycoprotein
title_fullStr A mouse attenuated mutant of Junin virus with an altered envelope glycoprotein
title_full_unstemmed A mouse attenuated mutant of Junin virus with an altered envelope glycoprotein
title_sort mouse attenuated mutant of junin virus with an altered envelope glycoprotein
url http://hdl.handle.net/20.500.12110/paper_03048608_v111_n3-4_p257_Scolaro
work_keys_str_mv AT scolarola amouseattenuatedmutantofjuninviruswithanalteredenvelopeglycoprotein
AT mersichse amouseattenuatedmutantofjuninviruswithanalteredenvelopeglycoprotein
AT damonteeb amouseattenuatedmutantofjuninviruswithanalteredenvelopeglycoprotein
AT scolarola mouseattenuatedmutantofjuninviruswithanalteredenvelopeglycoprotein
AT mersichse mouseattenuatedmutantofjuninviruswithanalteredenvelopeglycoprotein
AT damonteeb mouseattenuatedmutantofjuninviruswithanalteredenvelopeglycoprotein
_version_ 1807320848884826112

Ejemplares similares