DNA topoisomerase I from Leydig cells is modulated by luteinizing hormone and cyclic adenosine monophosphate
The action of luteinizing hormone on topoisomerase I activity from rat Leydig cells was studied. Stimulation of the enzyme was observed after long-term (24 and 48 h) gonadotrophin treatment in in vivo experiments. No change could be detected for shorter times than 12 h using two different experiment...
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| Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_03037207_v53_n3_p221_Crespi |
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todo:paper_03037207_v53_n3_p221_Crespi2023-10-03T15:20:00Z DNA topoisomerase I from Leydig cells is modulated by luteinizing hormone and cyclic adenosine monophosphate Crespi, M.D. Radicella, J.P. Baldi, A. Charreau, E.H. Calvo, J.C. DNA topoisomerase I Leydig cell Nuclear effect Peptide hormone cyclic amp dna dna topoisomerase luteinizing hormone peptide animal cell leydig cell male genital system nonhuman nucleus priority journal rat Animals Carrier Proteins Cyclic AMP DNA Topoisomerases, Type I Gonadotropins Intracellular Signaling Peptides and Proteins Leydig Cells Luteinizing Hormone Male Rats Rats, Inbred Strains Testosterone The action of luteinizing hormone on topoisomerase I activity from rat Leydig cells was studied. Stimulation of the enzyme was observed after long-term (24 and 48 h) gonadotrophin treatment in in vivo experiments. No change could be detected for shorter times than 12 h using two different experimental approaches. Topoisomerase I was stimulated by cAMP in a whole cell extract in a phosphorylation-dependent manner. These results suggest that topoisomerase I could be a target for nuclear events induced by peptide hormone action. © 1987. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_03037207_v53_n3_p221_Crespi |
| institution |
Universidad de Buenos Aires |
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I-28 |
| repository_str |
R-134 |
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Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
DNA topoisomerase I Leydig cell Nuclear effect Peptide hormone cyclic amp dna dna topoisomerase luteinizing hormone peptide animal cell leydig cell male genital system nonhuman nucleus priority journal rat Animals Carrier Proteins Cyclic AMP DNA Topoisomerases, Type I Gonadotropins Intracellular Signaling Peptides and Proteins Leydig Cells Luteinizing Hormone Male Rats Rats, Inbred Strains Testosterone |
| spellingShingle |
DNA topoisomerase I Leydig cell Nuclear effect Peptide hormone cyclic amp dna dna topoisomerase luteinizing hormone peptide animal cell leydig cell male genital system nonhuman nucleus priority journal rat Animals Carrier Proteins Cyclic AMP DNA Topoisomerases, Type I Gonadotropins Intracellular Signaling Peptides and Proteins Leydig Cells Luteinizing Hormone Male Rats Rats, Inbred Strains Testosterone Crespi, M.D. Radicella, J.P. Baldi, A. Charreau, E.H. Calvo, J.C. DNA topoisomerase I from Leydig cells is modulated by luteinizing hormone and cyclic adenosine monophosphate |
| topic_facet |
DNA topoisomerase I Leydig cell Nuclear effect Peptide hormone cyclic amp dna dna topoisomerase luteinizing hormone peptide animal cell leydig cell male genital system nonhuman nucleus priority journal rat Animals Carrier Proteins Cyclic AMP DNA Topoisomerases, Type I Gonadotropins Intracellular Signaling Peptides and Proteins Leydig Cells Luteinizing Hormone Male Rats Rats, Inbred Strains Testosterone |
| description |
The action of luteinizing hormone on topoisomerase I activity from rat Leydig cells was studied. Stimulation of the enzyme was observed after long-term (24 and 48 h) gonadotrophin treatment in in vivo experiments. No change could be detected for shorter times than 12 h using two different experimental approaches. Topoisomerase I was stimulated by cAMP in a whole cell extract in a phosphorylation-dependent manner. These results suggest that topoisomerase I could be a target for nuclear events induced by peptide hormone action. © 1987. |
| format |
JOUR |
| author |
Crespi, M.D. Radicella, J.P. Baldi, A. Charreau, E.H. Calvo, J.C. |
| author_facet |
Crespi, M.D. Radicella, J.P. Baldi, A. Charreau, E.H. Calvo, J.C. |
| author_sort |
Crespi, M.D. |
| title |
DNA topoisomerase I from Leydig cells is modulated by luteinizing hormone and cyclic adenosine monophosphate |
| title_short |
DNA topoisomerase I from Leydig cells is modulated by luteinizing hormone and cyclic adenosine monophosphate |
| title_full |
DNA topoisomerase I from Leydig cells is modulated by luteinizing hormone and cyclic adenosine monophosphate |
| title_fullStr |
DNA topoisomerase I from Leydig cells is modulated by luteinizing hormone and cyclic adenosine monophosphate |
| title_full_unstemmed |
DNA topoisomerase I from Leydig cells is modulated by luteinizing hormone and cyclic adenosine monophosphate |
| title_sort |
dna topoisomerase i from leydig cells is modulated by luteinizing hormone and cyclic adenosine monophosphate |
| url |
http://hdl.handle.net/20.500.12110/paper_03037207_v53_n3_p221_Crespi |
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