In vitro effects of adenohypophysial hormones on rat pineal melatonin content and release

The effect of adenohypophysial hormones on rat pineal melatonin content and release was examined in vitro. Medium concentration of radioimmunoassayable melatonin decreased after a 6 h exposure to 1-100 ng/ml FSH; pineal levels of melatonin were only decreased by 100 ng/ml FSH. LH (1-100 ng/ml) augme...

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Autores principales:	Vacas, M.I., Sarmiento, M.I.K., Pereyra, E.N., Etchegoyen, G.S., Cardinali, D.P.
Formato:	JOUR
Materias:	ACTH FSH Growth hormone LH Pineal organ culture Prolactin TSH adenohypophysis hormone corticotropin follitropin growth hormone luteinizing hormone melatonin prolactin radioisotope thyrotropin animal experiment central nervous system drug administration drug comparison drug dose drug efficacy endocrine system in vitro study methodology nonhuman pineal body preliminary communication priority journal radioimmunoassay rat Adrenocorticotropic Hormone Animals Follicle Stimulating Hormone Growth Hormone Luteinizing Hormone Male Melatonin Organ Culture Techniques Pineal Gland Pituitary Hormones, Anterior Rats Thyrotropin
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_03037207_v50_n1-2_p23_Vacas
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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spelling	todo:paper_03037207_v50_n1-2_p23_Vacas2023-10-03T15:20:00Z In vitro effects of adenohypophysial hormones on rat pineal melatonin content and release Vacas, M.I. Sarmiento, M.I.K. Pereyra, E.N. Etchegoyen, G.S. Cardinali, D.P. ACTH FSH Growth hormone LH Pineal organ culture Prolactin TSH adenohypophysis hormone corticotropin follitropin growth hormone luteinizing hormone melatonin prolactin radioisotope thyrotropin animal experiment central nervous system drug administration drug comparison drug dose drug efficacy endocrine system in vitro study methodology nonhuman pineal body preliminary communication priority journal radioimmunoassay rat Adrenocorticotropic Hormone Animals Follicle Stimulating Hormone Growth Hormone Luteinizing Hormone Male Melatonin Organ Culture Techniques Pineal Gland Pituitary Hormones, Anterior Prolactin Rats Thyrotropin The effect of adenohypophysial hormones on rat pineal melatonin content and release was examined in vitro. Medium concentration of radioimmunoassayable melatonin decreased after a 6 h exposure to 1-100 ng/ml FSH; pineal levels of melatonin were only decreased by 100 ng/ml FSH. LH (1-100 ng/ml) augmented significantly medium melatonin concentration, tissue levels being increased at 10 ng/ml LH. Parallel increases of explant and medium melatonin content were found after exposure to 1-100 ng/ml TSH. At the smallest concentration employed (1 ng/ml) prolactin increased melatonin content and release while at 100 ng/ml a significant depression of both parameters was found. Growth hormone (1-10 ng/ml) augmented melatonin levels in medium but failed to modify them at 100 ng/ml, although at this concentration tissue melatonin levels increased. ACTH did not modify pineal melatonin synthesis in vitro. © 1987. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_03037207_v50_n1-2_p23_Vacas
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	ACTH FSH Growth hormone LH Pineal organ culture Prolactin TSH adenohypophysis hormone corticotropin follitropin growth hormone luteinizing hormone melatonin prolactin radioisotope thyrotropin animal experiment central nervous system drug administration drug comparison drug dose drug efficacy endocrine system in vitro study methodology nonhuman pineal body preliminary communication priority journal radioimmunoassay rat Adrenocorticotropic Hormone Animals Follicle Stimulating Hormone Growth Hormone Luteinizing Hormone Male Melatonin Organ Culture Techniques Pineal Gland Pituitary Hormones, Anterior Prolactin Rats Thyrotropin
spellingShingle	ACTH FSH Growth hormone LH Pineal organ culture Prolactin TSH adenohypophysis hormone corticotropin follitropin growth hormone luteinizing hormone melatonin prolactin radioisotope thyrotropin animal experiment central nervous system drug administration drug comparison drug dose drug efficacy endocrine system in vitro study methodology nonhuman pineal body preliminary communication priority journal radioimmunoassay rat Adrenocorticotropic Hormone Animals Follicle Stimulating Hormone Growth Hormone Luteinizing Hormone Male Melatonin Organ Culture Techniques Pineal Gland Pituitary Hormones, Anterior Prolactin Rats Thyrotropin Vacas, M.I. Sarmiento, M.I.K. Pereyra, E.N. Etchegoyen, G.S. Cardinali, D.P. In vitro effects of adenohypophysial hormones on rat pineal melatonin content and release
topic_facet	ACTH FSH Growth hormone LH Pineal organ culture Prolactin TSH adenohypophysis hormone corticotropin follitropin growth hormone luteinizing hormone melatonin prolactin radioisotope thyrotropin animal experiment central nervous system drug administration drug comparison drug dose drug efficacy endocrine system in vitro study methodology nonhuman pineal body preliminary communication priority journal radioimmunoassay rat Adrenocorticotropic Hormone Animals Follicle Stimulating Hormone Growth Hormone Luteinizing Hormone Male Melatonin Organ Culture Techniques Pineal Gland Pituitary Hormones, Anterior Prolactin Rats Thyrotropin
description	The effect of adenohypophysial hormones on rat pineal melatonin content and release was examined in vitro. Medium concentration of radioimmunoassayable melatonin decreased after a 6 h exposure to 1-100 ng/ml FSH; pineal levels of melatonin were only decreased by 100 ng/ml FSH. LH (1-100 ng/ml) augmented significantly medium melatonin concentration, tissue levels being increased at 10 ng/ml LH. Parallel increases of explant and medium melatonin content were found after exposure to 1-100 ng/ml TSH. At the smallest concentration employed (1 ng/ml) prolactin increased melatonin content and release while at 100 ng/ml a significant depression of both parameters was found. Growth hormone (1-10 ng/ml) augmented melatonin levels in medium but failed to modify them at 100 ng/ml, although at this concentration tissue melatonin levels increased. ACTH did not modify pineal melatonin synthesis in vitro. © 1987.
format	JOUR
author	Vacas, M.I. Sarmiento, M.I.K. Pereyra, E.N. Etchegoyen, G.S. Cardinali, D.P.
author_facet	Vacas, M.I. Sarmiento, M.I.K. Pereyra, E.N. Etchegoyen, G.S. Cardinali, D.P.
author_sort	Vacas, M.I.
title	In vitro effects of adenohypophysial hormones on rat pineal melatonin content and release
title_short	In vitro effects of adenohypophysial hormones on rat pineal melatonin content and release
title_full	In vitro effects of adenohypophysial hormones on rat pineal melatonin content and release
title_fullStr	In vitro effects of adenohypophysial hormones on rat pineal melatonin content and release
title_full_unstemmed	In vitro effects of adenohypophysial hormones on rat pineal melatonin content and release
title_sort	in vitro effects of adenohypophysial hormones on rat pineal melatonin content and release
url	http://hdl.handle.net/20.500.12110/paper_03037207_v50_n1-2_p23_Vacas
work_keys_str_mv	AT vacasmi invitroeffectsofadenohypophysialhormonesonratpinealmelatonincontentandrelease AT sarmientomik invitroeffectsofadenohypophysialhormonesonratpinealmelatonincontentandrelease AT pereyraen invitroeffectsofadenohypophysialhormonesonratpinealmelatonincontentandrelease AT etchegoyengs invitroeffectsofadenohypophysialhormonesonratpinealmelatonincontentandrelease AT cardinalidp invitroeffectsofadenohypophysialhormonesonratpinealmelatonincontentandrelease
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In vitro effects of adenohypophysial hormones on rat pineal melatonin content and release

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