Extracellular matrix components regulate ACTH production and proliferation in corticotroph tumor cells

The extracellular matrix (ECM) conveys signals through membrane receptors called integrins producing changes in cell morphology, proliferation, differentiation and apoptosis. Previous studies suggest that the ECM plays an important role in pituitary physiology and tumorigenesis. In the present work...

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Detalles Bibliográficos
Autores principales: Kuchenbauer, F., Hopfner, U., Stalla, J., Arzt, E., Stalla, G.K., Páez-Pereda, M.
Formato: JOUR
Materias:
ACTH
Corticotroph cells
Extracellular matrix
Integrins
POMC
Reactive oxygen species
collagen type 1
collagen type 4
corticotropin
fibronectin
integrin
laminin
reactive oxygen metabolite
article
cell proliferation
cell structure
controlled study
corticotropin release
extracellular matrix
genetic transcription
hormone release
human
human cell
hypophysis cell
priority journal
signal transduction
tumor cell
Adrenocorticotropic Hormone
Animals
Cell Division
Collagen
Extracellular Matrix
Fibronectins
Laminin
Mice
Pituitary Neoplasms
Pro-Opiomelanocortin
Promoter Regions (Genetics)
Transcription, Genetic
Tumor Cells, Cultured
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_03037207_v175_n1-2_p141_Kuchenbauer
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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