Expression of the UGA4 gene encoding the δ-aminolevulinic and γ-aminobutyric acids permease in Saccharomyces cerevisiae is controlled by amino acid-sensing systems
In yeasts, several sensing systems localized to the plasma membrane which transduce information regarding the availability and quality of nitrogen and carbon sources and work in parallel with the intracellular nutrient-sensing systems, regulate the expression and activity of proteins involved in nut...
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todo:paper_03028933_v184_n2_p137_BermudezMoretti2023-10-03T15:18:44Z Expression of the UGA4 gene encoding the δ-aminolevulinic and γ-aminobutyric acids permease in Saccharomyces cerevisiae is controlled by amino acid-sensing systems Bermudez Moretti, M. Perullini, A.M. Batlle, A. Correa Garcia, S. Gene expression Saccharomyces cerevisiae Sensor systems UGA4 gene 4 aminobutyric acid amino acid aminolevulinic acid article gene gene control gene expression molecular dynamics nonhuman priority journal regulatory mechanism Saccharomyces cerevisiae signal transduction UGA4 gene Amino Acid Transport Systems Aminolevulinic Acid Carrier Proteins GABA Plasma Membrane Transport Proteins gamma-Aminobutyric Acid Gene Expression Regulation, Fungal Membrane Proteins Organic Anion Transporters Saccharomyces cerevisiae Proteins Saccharomyces cerevisiae In yeasts, several sensing systems localized to the plasma membrane which transduce information regarding the availability and quality of nitrogen and carbon sources and work in parallel with the intracellular nutrient-sensing systems, regulate the expression and activity of proteins involved in nutrient uptake and utilization. The aim of this work was to establish whether the cellular signals triggered by amino acids modify the expression of the UGA4 gene which encodes the δ-aminolevulinic (ALA) and γ-aminobutyric (GABA) acids permease. In the present paper, we demonstrate that extracellular amino acids regulate UGA4 expression and that this effect seems to be mediated by the amino acid sensor complex SPS (SSY1, PTR3, SSY5). © Springer-Verlag 2005. Fil:Bermudez Moretti, M. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Perullini, A.M. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Batlle, A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Correa Garcia, S. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_03028933_v184_n2_p137_BermudezMoretti |
institution |
Universidad de Buenos Aires |
institution_str |
I-28 |
repository_str |
R-134 |
collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
topic |
Gene expression Saccharomyces cerevisiae Sensor systems UGA4 gene 4 aminobutyric acid amino acid aminolevulinic acid article gene gene control gene expression molecular dynamics nonhuman priority journal regulatory mechanism Saccharomyces cerevisiae signal transduction UGA4 gene Amino Acid Transport Systems Aminolevulinic Acid Carrier Proteins GABA Plasma Membrane Transport Proteins gamma-Aminobutyric Acid Gene Expression Regulation, Fungal Membrane Proteins Organic Anion Transporters Saccharomyces cerevisiae Proteins Saccharomyces cerevisiae |
spellingShingle |
Gene expression Saccharomyces cerevisiae Sensor systems UGA4 gene 4 aminobutyric acid amino acid aminolevulinic acid article gene gene control gene expression molecular dynamics nonhuman priority journal regulatory mechanism Saccharomyces cerevisiae signal transduction UGA4 gene Amino Acid Transport Systems Aminolevulinic Acid Carrier Proteins GABA Plasma Membrane Transport Proteins gamma-Aminobutyric Acid Gene Expression Regulation, Fungal Membrane Proteins Organic Anion Transporters Saccharomyces cerevisiae Proteins Saccharomyces cerevisiae Bermudez Moretti, M. Perullini, A.M. Batlle, A. Correa Garcia, S. Expression of the UGA4 gene encoding the δ-aminolevulinic and γ-aminobutyric acids permease in Saccharomyces cerevisiae is controlled by amino acid-sensing systems |
topic_facet |
Gene expression Saccharomyces cerevisiae Sensor systems UGA4 gene 4 aminobutyric acid amino acid aminolevulinic acid article gene gene control gene expression molecular dynamics nonhuman priority journal regulatory mechanism Saccharomyces cerevisiae signal transduction UGA4 gene Amino Acid Transport Systems Aminolevulinic Acid Carrier Proteins GABA Plasma Membrane Transport Proteins gamma-Aminobutyric Acid Gene Expression Regulation, Fungal Membrane Proteins Organic Anion Transporters Saccharomyces cerevisiae Proteins Saccharomyces cerevisiae |
description |
In yeasts, several sensing systems localized to the plasma membrane which transduce information regarding the availability and quality of nitrogen and carbon sources and work in parallel with the intracellular nutrient-sensing systems, regulate the expression and activity of proteins involved in nutrient uptake and utilization. The aim of this work was to establish whether the cellular signals triggered by amino acids modify the expression of the UGA4 gene which encodes the δ-aminolevulinic (ALA) and γ-aminobutyric (GABA) acids permease. In the present paper, we demonstrate that extracellular amino acids regulate UGA4 expression and that this effect seems to be mediated by the amino acid sensor complex SPS (SSY1, PTR3, SSY5). © Springer-Verlag 2005. |
format |
JOUR |
author |
Bermudez Moretti, M. Perullini, A.M. Batlle, A. Correa Garcia, S. |
author_facet |
Bermudez Moretti, M. Perullini, A.M. Batlle, A. Correa Garcia, S. |
author_sort |
Bermudez Moretti, M. |
title |
Expression of the UGA4 gene encoding the δ-aminolevulinic and γ-aminobutyric acids permease in Saccharomyces cerevisiae is controlled by amino acid-sensing systems |
title_short |
Expression of the UGA4 gene encoding the δ-aminolevulinic and γ-aminobutyric acids permease in Saccharomyces cerevisiae is controlled by amino acid-sensing systems |
title_full |
Expression of the UGA4 gene encoding the δ-aminolevulinic and γ-aminobutyric acids permease in Saccharomyces cerevisiae is controlled by amino acid-sensing systems |
title_fullStr |
Expression of the UGA4 gene encoding the δ-aminolevulinic and γ-aminobutyric acids permease in Saccharomyces cerevisiae is controlled by amino acid-sensing systems |
title_full_unstemmed |
Expression of the UGA4 gene encoding the δ-aminolevulinic and γ-aminobutyric acids permease in Saccharomyces cerevisiae is controlled by amino acid-sensing systems |
title_sort |
expression of the uga4 gene encoding the δ-aminolevulinic and γ-aminobutyric acids permease in saccharomyces cerevisiae is controlled by amino acid-sensing systems |
url |
http://hdl.handle.net/20.500.12110/paper_03028933_v184_n2_p137_BermudezMoretti |
work_keys_str_mv |
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