Norepinephrine turnover in pineal gland and superior cervical ganglia. Changes after gonadotrophin administration to castrated rats

The effects of FSH and LH on norepinephrine (NE) turnover in pineal gland and superior cervical ganglia of castrated female rats were examined by measuring the decline of [3H]NE concentration in the organ 30-120 min after a single i.v. injection of the labeled amine. Both FSH and LH treatment signif...

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Autores principales:	Cardinali, D.P., Vacas, M.I.
Formato:	JOUR
Materias:	FSH LH norepinephrine metabolism pineal gland superior cervical ganglion estradiol follitropin luteinizing hormone noradrenalin testosterone animal experiment autonomic nervous system castration endocrine system noradrenalin h 3 phenethylamine c 14 pineal body rat serotonin c 14 Adrenal Glands Animal Castration Female Follicle Stimulating Hormone Ganglia, Sympathetic Luteinizing Hormone Monoamine Oxidase Myocardium Phenethylamines Pineal Gland Rats Serotonin
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_03009564_v45_n4_p273_Cardinali
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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spelling	todo:paper_03009564_v45_n4_p273_Cardinali2023-10-03T15:18:02Z Norepinephrine turnover in pineal gland and superior cervical ganglia. Changes after gonadotrophin administration to castrated rats Cardinali, D.P. Vacas, M.I. FSH LH norepinephrine metabolism pineal gland superior cervical ganglion estradiol follitropin luteinizing hormone noradrenalin testosterone animal experiment autonomic nervous system castration endocrine system noradrenalin h 3 phenethylamine c 14 pineal body rat serotonin c 14 superior cervical ganglion Adrenal Glands Animal Castration Female Follicle Stimulating Hormone Ganglia, Sympathetic Luteinizing Hormone Monoamine Oxidase Myocardium Phenethylamines Pineal Gland Rats Serotonin The effects of FSH and LH on norepinephrine (NE) turnover in pineal gland and superior cervical ganglia of castrated female rats were examined by measuring the decline of [3H]NE concentration in the organ 30-120 min after a single i.v. injection of the labeled amine. Both FSH and LH treatment significantly decreased [3H]NE turnover in the pineal gland whereas only FSH accelerated it in the ganglia. As compared to controls, the initial uptake of [3H]NE was lower in the pineal gland of FSH- and LH-treated animals, and higher in the superior cervical ganglia of rats injected with FSH. Neither FSH nor LH modified [3H]NE turnover in heart or adrenal gland, nor changed their endogenous catecholamine content. Pineal monoamine oxidase (MAO) activity type B (assaying by using β-phenylethylamine as substrate) was decreased by FSH or LH injection. Only FSH modified MAO activity in the ganglia by increasing significantly type A enzyme (assaying by using serotonin as substrate). These results suggest that FSH and LH affect significantly NE metabolism in pineal gland and superior cervical ganglia of spayed rats. © 1979 Springer-Verlag. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_03009564_v45_n4_p273_Cardinali
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	FSH LH norepinephrine metabolism pineal gland superior cervical ganglion estradiol follitropin luteinizing hormone noradrenalin testosterone animal experiment autonomic nervous system castration endocrine system noradrenalin h 3 phenethylamine c 14 pineal body rat serotonin c 14 superior cervical ganglion Adrenal Glands Animal Castration Female Follicle Stimulating Hormone Ganglia, Sympathetic Luteinizing Hormone Monoamine Oxidase Myocardium Phenethylamines Pineal Gland Rats Serotonin
spellingShingle	FSH LH norepinephrine metabolism pineal gland superior cervical ganglion estradiol follitropin luteinizing hormone noradrenalin testosterone animal experiment autonomic nervous system castration endocrine system noradrenalin h 3 phenethylamine c 14 pineal body rat serotonin c 14 superior cervical ganglion Adrenal Glands Animal Castration Female Follicle Stimulating Hormone Ganglia, Sympathetic Luteinizing Hormone Monoamine Oxidase Myocardium Phenethylamines Pineal Gland Rats Serotonin Cardinali, D.P. Vacas, M.I. Norepinephrine turnover in pineal gland and superior cervical ganglia. Changes after gonadotrophin administration to castrated rats
topic_facet	FSH LH norepinephrine metabolism pineal gland superior cervical ganglion estradiol follitropin luteinizing hormone noradrenalin testosterone animal experiment autonomic nervous system castration endocrine system noradrenalin h 3 phenethylamine c 14 pineal body rat serotonin c 14 superior cervical ganglion Adrenal Glands Animal Castration Female Follicle Stimulating Hormone Ganglia, Sympathetic Luteinizing Hormone Monoamine Oxidase Myocardium Phenethylamines Pineal Gland Rats Serotonin
description	The effects of FSH and LH on norepinephrine (NE) turnover in pineal gland and superior cervical ganglia of castrated female rats were examined by measuring the decline of [3H]NE concentration in the organ 30-120 min after a single i.v. injection of the labeled amine. Both FSH and LH treatment significantly decreased [3H]NE turnover in the pineal gland whereas only FSH accelerated it in the ganglia. As compared to controls, the initial uptake of [3H]NE was lower in the pineal gland of FSH- and LH-treated animals, and higher in the superior cervical ganglia of rats injected with FSH. Neither FSH nor LH modified [3H]NE turnover in heart or adrenal gland, nor changed their endogenous catecholamine content. Pineal monoamine oxidase (MAO) activity type B (assaying by using β-phenylethylamine as substrate) was decreased by FSH or LH injection. Only FSH modified MAO activity in the ganglia by increasing significantly type A enzyme (assaying by using serotonin as substrate). These results suggest that FSH and LH affect significantly NE metabolism in pineal gland and superior cervical ganglia of spayed rats. © 1979 Springer-Verlag.
format	JOUR
author	Cardinali, D.P. Vacas, M.I.
author_facet	Cardinali, D.P. Vacas, M.I.
author_sort	Cardinali, D.P.
title	Norepinephrine turnover in pineal gland and superior cervical ganglia. Changes after gonadotrophin administration to castrated rats
title_short	Norepinephrine turnover in pineal gland and superior cervical ganglia. Changes after gonadotrophin administration to castrated rats
title_full	Norepinephrine turnover in pineal gland and superior cervical ganglia. Changes after gonadotrophin administration to castrated rats
title_fullStr	Norepinephrine turnover in pineal gland and superior cervical ganglia. Changes after gonadotrophin administration to castrated rats
title_full_unstemmed	Norepinephrine turnover in pineal gland and superior cervical ganglia. Changes after gonadotrophin administration to castrated rats
title_sort	norepinephrine turnover in pineal gland and superior cervical ganglia. changes after gonadotrophin administration to castrated rats
url	http://hdl.handle.net/20.500.12110/paper_03009564_v45_n4_p273_Cardinali
work_keys_str_mv	AT cardinalidp norepinephrineturnoverinpinealglandandsuperiorcervicalgangliachangesaftergonadotrophinadministrationtocastratedrats AT vacasmi norepinephrineturnoverinpinealglandandsuperiorcervicalgangliachangesaftergonadotrophinadministrationtocastratedrats
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Norepinephrine turnover in pineal gland and superior cervical ganglia. Changes after gonadotrophin administration to castrated rats

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