Mechanism of protein synthesis inhibition during stationary phase in Bacillus stearothermophil US

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The appearance of a protein (association factor I) in ribosomes from Bacillus stearothermophilus at stationary phase of growth is described. Association factor I is present on 30S subunits and 30S-50S ribosomal couples, but not on 50S subunits. This protein is responsible for the low levels of polyp...

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Autor principal:	Garcia-Patrone, M.
Formato:	JOUR
Materias:	animal experiment bacillus stearothermophilus in vitro study protein synthesis Bacillus stearothermophilus Bacterial Proteins Cell Cycle Coliphages Peptide Chain Initiation Peptide Synthesis Phenylalanine Poly U Ribosomal Proteins Ribosomes RNA, Messenger RNA, Viral
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_03008177_v31_n2_p97_GarciaPatrone
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

id	todo:paper_03008177_v31_n2_p97_GarciaPatrone
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spelling	todo:paper_03008177_v31_n2_p97_GarciaPatrone2023-10-03T15:17:46Z Mechanism of protein synthesis inhibition during stationary phase in Bacillus stearothermophil US Garcia-Patrone, M. animal experiment bacillus stearothermophilus in vitro study protein synthesis Bacillus stearothermophilus Bacterial Proteins Cell Cycle Coliphages Peptide Chain Initiation Peptide Synthesis Phenylalanine Poly U Ribosomal Proteins Ribosomes RNA, Messenger RNA, Viral The appearance of a protein (association factor I) in ribosomes from Bacillus stearothermophilus at stationary phase of growth is described. Association factor I is present on 30S subunits and 30S-50S ribosomal couples, but not on 50S subunits. This protein is responsible for the low levels of polyphenylalanine synthesis shown by stationary phase ribosomes. Association factor I is able to bind to free 30S-50S ribosomal couples but not to polysomes, and exerts its effect by inhibiting the initiation step of protein synthesis. Ribosomes preincubated with association factor I have a decreased ability for polypeptide snythesis directed phage mRNA or poly(U). © 1980 Dr. W. Junk b.v. Publishers. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_03008177_v31_n2_p97_GarciaPatrone
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	animal experiment bacillus stearothermophilus in vitro study protein synthesis Bacillus stearothermophilus Bacterial Proteins Cell Cycle Coliphages Peptide Chain Initiation Peptide Synthesis Phenylalanine Poly U Ribosomal Proteins Ribosomes RNA, Messenger RNA, Viral
spellingShingle	animal experiment bacillus stearothermophilus in vitro study protein synthesis Bacillus stearothermophilus Bacterial Proteins Cell Cycle Coliphages Peptide Chain Initiation Peptide Synthesis Phenylalanine Poly U Ribosomal Proteins Ribosomes RNA, Messenger RNA, Viral Garcia-Patrone, M. Mechanism of protein synthesis inhibition during stationary phase in Bacillus stearothermophil US
topic_facet	animal experiment bacillus stearothermophilus in vitro study protein synthesis Bacillus stearothermophilus Bacterial Proteins Cell Cycle Coliphages Peptide Chain Initiation Peptide Synthesis Phenylalanine Poly U Ribosomal Proteins Ribosomes RNA, Messenger RNA, Viral
description	The appearance of a protein (association factor I) in ribosomes from Bacillus stearothermophilus at stationary phase of growth is described. Association factor I is present on 30S subunits and 30S-50S ribosomal couples, but not on 50S subunits. This protein is responsible for the low levels of polyphenylalanine synthesis shown by stationary phase ribosomes. Association factor I is able to bind to free 30S-50S ribosomal couples but not to polysomes, and exerts its effect by inhibiting the initiation step of protein synthesis. Ribosomes preincubated with association factor I have a decreased ability for polypeptide snythesis directed phage mRNA or poly(U). © 1980 Dr. W. Junk b.v. Publishers.
format	JOUR
author	Garcia-Patrone, M.
author_facet	Garcia-Patrone, M.
author_sort	Garcia-Patrone, M.
title	Mechanism of protein synthesis inhibition during stationary phase in Bacillus stearothermophil US
title_short	Mechanism of protein synthesis inhibition during stationary phase in Bacillus stearothermophil US
title_full	Mechanism of protein synthesis inhibition during stationary phase in Bacillus stearothermophil US
title_fullStr	Mechanism of protein synthesis inhibition during stationary phase in Bacillus stearothermophil US
title_full_unstemmed	Mechanism of protein synthesis inhibition during stationary phase in Bacillus stearothermophil US
title_sort	mechanism of protein synthesis inhibition during stationary phase in bacillus stearothermophil us
url	http://hdl.handle.net/20.500.12110/paper_03008177_v31_n2_p97_GarciaPatrone
work_keys_str_mv	AT garciapatronem mechanismofproteinsynthesisinhibitionduringstationaryphaseinbacillusstearothermophilus
_version_	1807319301782241280

Mechanism of protein synthesis inhibition during stationary phase in Bacillus stearothermophil US

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