Hexachlorobenzene-induced alterations of rat hepatic microsomal membrane function

The time and dose-dependent effects of the in vivo administration of hexachlorobenzene (HCB), on hepatic microsomal membrane functions, were studied in female Wistar rats. Administration of HCB (100 mg/100 g b.w.) resulted in time-dependent decreases in the activity of two membrane-bound enzymes: 5&...

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Detalles Bibliográficos
Autores principales: Randi, A.S., Sancovich, H.A., Ferramola De Sancovich, A.M., Loaiza, A., Krawiec, L., Kleiman De Pisarev, D.L.
Formato: JOUR
Materias:
Epidermal growth factor receptor
Hexachlorobenzene
Mechanism of action
Membrane protein phosphorylation
Protein tyrosine kinase
epidermal growth factor receptor
hexachlorobenzene
protein tyrosine kinase
animal experiment
article
dose response
drug effect
enzyme activation
enzyme activity
female
liver microsome
liver toxicity
nonhuman
priority journal
protein phosphorylation
rat
5'-Nucleotidase
Animals
Dose-Response Relationship, Drug
Epidermal Growth Factor
Female
Intracellular Membranes
Microsomes, Liver
Na(+)-K(+)-Exchanging ATPase
Phosphorylation
Protein-Tyrosine Kinases
Rats
Rats, Wistar
Receptor, Epidermal Growth Factor
Soil Pollutants
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_0300483X_v125_n2-3_p83_Randi
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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