The Molecular Weights and Molecular Weight Heterodispersion of Some Antigens From the Trichloroacetic Acid Soluble Fraction of Human Seminal Plasma

ABSTRACT: The antigens isolated from the trichloroacetic acid soluble fraction of human seminal plasma show a polymodal molecular weight heterodispersion. The molecular weights corresponding to the modes of the distribution have limiting values of 2,500‐57,000. Previous results obtained by polyacryl...

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Autores principales: DE CEREZO, J.M.S., CEREZO, A.S.
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Acceso en línea:http://hdl.handle.net/20.500.12110/paper_02717352_v1_n5_p266_DECEREZO
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spelling todo:paper_02717352_v1_n5_p266_DECEREZO2023-10-03T15:14:53Z The Molecular Weights and Molecular Weight Heterodispersion of Some Antigens From the Trichloroacetic Acid Soluble Fraction of Human Seminal Plasma DE CEREZO, J.M.S. CEREZO, A.S. antigens human seminal plasma Molecular weight heterodispersion trichloroacetic soluble fraction trichloroacetic acid male genital system normal human sperm ABSTRACT: The antigens isolated from the trichloroacetic acid soluble fraction of human seminal plasma show a polymodal molecular weight heterodispersion. The molecular weights corresponding to the modes of the distribution have limiting values of 2,500‐57,000. Previous results obtained by polyacrylamide gel and cellogel electrophoresis, immunodiffusion and Immunoelectrophoresis, and ultracentrifugation analysis, which suggested homogeneity, were explained by the formation of molecular aggregates, which would also explain why the smaller fragments were not lost during the dialysis carried out in the preparation and purification of the samples. The average molecular weight of the antigens, determined by gel permeation chromatography and using the equation of Svedberg, is in the range of 10,000–40,000. It is suggested that the polymodal heterodispersion together with the associating‐dissociating properties of these products is used to control their immunological behavior. 1981 Munksgaard Fil:CEREZO, A.S. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_02717352_v1_n5_p266_DECEREZO
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic antigens
human seminal plasma
Molecular weight heterodispersion
trichloroacetic soluble fraction
trichloroacetic acid
male genital system
normal human
sperm
spellingShingle antigens
human seminal plasma
Molecular weight heterodispersion
trichloroacetic soluble fraction
trichloroacetic acid
male genital system
normal human
sperm
DE CEREZO, J.M.S.
CEREZO, A.S.
The Molecular Weights and Molecular Weight Heterodispersion of Some Antigens From the Trichloroacetic Acid Soluble Fraction of Human Seminal Plasma
topic_facet antigens
human seminal plasma
Molecular weight heterodispersion
trichloroacetic soluble fraction
trichloroacetic acid
male genital system
normal human
sperm
description ABSTRACT: The antigens isolated from the trichloroacetic acid soluble fraction of human seminal plasma show a polymodal molecular weight heterodispersion. The molecular weights corresponding to the modes of the distribution have limiting values of 2,500‐57,000. Previous results obtained by polyacrylamide gel and cellogel electrophoresis, immunodiffusion and Immunoelectrophoresis, and ultracentrifugation analysis, which suggested homogeneity, were explained by the formation of molecular aggregates, which would also explain why the smaller fragments were not lost during the dialysis carried out in the preparation and purification of the samples. The average molecular weight of the antigens, determined by gel permeation chromatography and using the equation of Svedberg, is in the range of 10,000–40,000. It is suggested that the polymodal heterodispersion together with the associating‐dissociating properties of these products is used to control their immunological behavior. 1981 Munksgaard
format JOUR
author DE CEREZO, J.M.S.
CEREZO, A.S.
author_facet DE CEREZO, J.M.S.
CEREZO, A.S.
author_sort DE CEREZO, J.M.S.
title The Molecular Weights and Molecular Weight Heterodispersion of Some Antigens From the Trichloroacetic Acid Soluble Fraction of Human Seminal Plasma
title_short The Molecular Weights and Molecular Weight Heterodispersion of Some Antigens From the Trichloroacetic Acid Soluble Fraction of Human Seminal Plasma
title_full The Molecular Weights and Molecular Weight Heterodispersion of Some Antigens From the Trichloroacetic Acid Soluble Fraction of Human Seminal Plasma
title_fullStr The Molecular Weights and Molecular Weight Heterodispersion of Some Antigens From the Trichloroacetic Acid Soluble Fraction of Human Seminal Plasma
title_full_unstemmed The Molecular Weights and Molecular Weight Heterodispersion of Some Antigens From the Trichloroacetic Acid Soluble Fraction of Human Seminal Plasma
title_sort molecular weights and molecular weight heterodispersion of some antigens from the trichloroacetic acid soluble fraction of human seminal plasma
url http://hdl.handle.net/20.500.12110/paper_02717352_v1_n5_p266_DECEREZO
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