Effect of dietary fish oil on mouse ocular Herpes Simplex type I infection

Balb/c mice fed a diet containing 20% fish oil developed herpes stromal keratitis earlier and with more severe lesions than control group. Peritoneal macrophages oxidative metabolism and intrinsic antiviral activity are not modified by diet manipulation but nitric oxide production was significantly...

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Autores principales:	Courrèges, M.Cecilia, Benencia, F., Monserrat, A.J.
Formato:	JOUR
Materias:	Fish oil Herpes Simplex type 1 Immune response Lymphocytes Macrophages Ocular keratitis corn oil fish oil animal experiment animal model article controlled study delayed hypersensitivity diet disease association disease course disease severity herpes simplex keratitis immune response lymphocyte proliferation mouse nonhuman priority journal T lymphocyte Herpes Human herpesvirus 1
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_02715317_v21_n1-2_p229_Courreges
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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spelling	todo:paper_02715317_v21_n1-2_p229_Courreges2023-10-03T15:14:52Z Effect of dietary fish oil on mouse ocular Herpes Simplex type I infection Courrèges, M.Cecilia Benencia, F. Monserrat, A.J. Fish oil Herpes Simplex type 1 Immune response Lymphocytes Macrophages Ocular keratitis corn oil fish oil animal experiment animal model article controlled study delayed hypersensitivity diet disease association disease course disease severity herpes simplex keratitis immune response lymphocyte proliferation mouse nonhuman priority journal T lymphocyte Herpes Human herpesvirus 1 Balb/c mice fed a diet containing 20% fish oil developed herpes stromal keratitis earlier and with more severe lesions than control group. Peritoneal macrophages oxidative metabolism and intrinsic antiviral activity are not modified by diet manipulation but nitric oxide production was significantly impaired. On the contrary, splenic lymphocytes proliferation stimulated "ex vivo" by heat inactivated HSV-1 is significantly increased as well as delayed type hypersensitivity. So, taking into account that herpes stromal keratitis is mediated by T cells, the effect of diet over these cells could be responsible for the observed exacerbation of the disease. © 2001 Elsevier Science Inc. Fil:Courrèges, M.Cecilia Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Benencia, F. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_02715317_v21_n1-2_p229_Courreges
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	Fish oil Herpes Simplex type 1 Immune response Lymphocytes Macrophages Ocular keratitis corn oil fish oil animal experiment animal model article controlled study delayed hypersensitivity diet disease association disease course disease severity herpes simplex keratitis immune response lymphocyte proliferation mouse nonhuman priority journal T lymphocyte Herpes Human herpesvirus 1
spellingShingle	Fish oil Herpes Simplex type 1 Immune response Lymphocytes Macrophages Ocular keratitis corn oil fish oil animal experiment animal model article controlled study delayed hypersensitivity diet disease association disease course disease severity herpes simplex keratitis immune response lymphocyte proliferation mouse nonhuman priority journal T lymphocyte Herpes Human herpesvirus 1 Courrèges, M.Cecilia Benencia, F. Monserrat, A.J. Effect of dietary fish oil on mouse ocular Herpes Simplex type I infection
topic_facet	Fish oil Herpes Simplex type 1 Immune response Lymphocytes Macrophages Ocular keratitis corn oil fish oil animal experiment animal model article controlled study delayed hypersensitivity diet disease association disease course disease severity herpes simplex keratitis immune response lymphocyte proliferation mouse nonhuman priority journal T lymphocyte Herpes Human herpesvirus 1
description	Balb/c mice fed a diet containing 20% fish oil developed herpes stromal keratitis earlier and with more severe lesions than control group. Peritoneal macrophages oxidative metabolism and intrinsic antiviral activity are not modified by diet manipulation but nitric oxide production was significantly impaired. On the contrary, splenic lymphocytes proliferation stimulated "ex vivo" by heat inactivated HSV-1 is significantly increased as well as delayed type hypersensitivity. So, taking into account that herpes stromal keratitis is mediated by T cells, the effect of diet over these cells could be responsible for the observed exacerbation of the disease. © 2001 Elsevier Science Inc.
format	JOUR
author	Courrèges, M.Cecilia Benencia, F. Monserrat, A.J.
author_facet	Courrèges, M.Cecilia Benencia, F. Monserrat, A.J.
author_sort	Courrèges, M.Cecilia
title	Effect of dietary fish oil on mouse ocular Herpes Simplex type I infection
title_short	Effect of dietary fish oil on mouse ocular Herpes Simplex type I infection
title_full	Effect of dietary fish oil on mouse ocular Herpes Simplex type I infection
title_fullStr	Effect of dietary fish oil on mouse ocular Herpes Simplex type I infection
title_full_unstemmed	Effect of dietary fish oil on mouse ocular Herpes Simplex type I infection
title_sort	effect of dietary fish oil on mouse ocular herpes simplex type i infection
url	http://hdl.handle.net/20.500.12110/paper_02715317_v21_n1-2_p229_Courreges
work_keys_str_mv	AT courregesmcecilia effectofdietaryfishoilonmouseocularherpessimplextypeiinfection AT benenciaf effectofdietaryfishoilonmouseocularherpessimplextypeiinfection AT monserrataj effectofdietaryfishoilonmouseocularherpessimplextypeiinfection
_version_	1782029070976942080

Effect of dietary fish oil on mouse ocular Herpes Simplex type I infection

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