Increasing the reliability of solution exchanges by monitoring solenoid valve actuation

Solenoid valves are a core component of most solution perfusion systems used in neuroscience research. As they open and close, they control the flow of solution through each perfusion line, thereby modulating the timing and sequence of chemical stimulation. The valves feature a ferromagnetic plunger...

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Autores principales: Auzmendi, J.A., Moffatt, L.
Formato: JOUR
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Acceso en línea:http://hdl.handle.net/20.500.12110/paper_01650270_v185_n2_p280_Auzmendi
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spelling todo:paper_01650270_v185_n2_p280_Auzmendi2023-10-03T15:02:35Z Increasing the reliability of solution exchanges by monitoring solenoid valve actuation Auzmendi, J.A. Moffatt, L. Concentration jump Patch clamp Perfusion Receptor kinetics Solenoid valve ferromagnetic material analytical equipment article atmospheric pressure electric potential observation priority journal process development process monitoring sensor signal detection solenoid systematic error Equipment Design Microfluidics Pulsatile Flow Reproducibility of Results Solutions Solenoid valves are a core component of most solution perfusion systems used in neuroscience research. As they open and close, they control the flow of solution through each perfusion line, thereby modulating the timing and sequence of chemical stimulation. The valves feature a ferromagnetic plunger that moves due to the magnetization of the solenoid and returns to its initial position with the aid of a spring. The delays between the time of voltage application or removal and the actual opening or closing of the valve are difficult to predict beforehand and have to be measured experimentally. Here we propose a simple method for monitoring whether and when the solenoid valve opens and closes. The proposed method detects the movement of the plunger as it generates a measurable signal on the solenoid that surrounds it. Using this plunger signal, we detected the opening and closing of diaphragm and pinch solenoid valves with a systematic error of less than 2 ms. After this systematic error is subtracted, the trial-to-trial error was below 0.2 ms. © 2009 Elsevier B.V. All rights reserved. Fil:Auzmendi, J.A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Moffatt, L. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_01650270_v185_n2_p280_Auzmendi
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic Concentration jump
Patch clamp
Perfusion
Receptor kinetics
Solenoid valve
ferromagnetic material
analytical equipment
article
atmospheric pressure
electric potential
observation
priority journal
process development
process monitoring
sensor
signal detection
solenoid
systematic error
Equipment Design
Microfluidics
Pulsatile Flow
Reproducibility of Results
Solutions
spellingShingle Concentration jump
Patch clamp
Perfusion
Receptor kinetics
Solenoid valve
ferromagnetic material
analytical equipment
article
atmospheric pressure
electric potential
observation
priority journal
process development
process monitoring
sensor
signal detection
solenoid
systematic error
Equipment Design
Microfluidics
Pulsatile Flow
Reproducibility of Results
Solutions
Auzmendi, J.A.
Moffatt, L.
Increasing the reliability of solution exchanges by monitoring solenoid valve actuation
topic_facet Concentration jump
Patch clamp
Perfusion
Receptor kinetics
Solenoid valve
ferromagnetic material
analytical equipment
article
atmospheric pressure
electric potential
observation
priority journal
process development
process monitoring
sensor
signal detection
solenoid
systematic error
Equipment Design
Microfluidics
Pulsatile Flow
Reproducibility of Results
Solutions
description Solenoid valves are a core component of most solution perfusion systems used in neuroscience research. As they open and close, they control the flow of solution through each perfusion line, thereby modulating the timing and sequence of chemical stimulation. The valves feature a ferromagnetic plunger that moves due to the magnetization of the solenoid and returns to its initial position with the aid of a spring. The delays between the time of voltage application or removal and the actual opening or closing of the valve are difficult to predict beforehand and have to be measured experimentally. Here we propose a simple method for monitoring whether and when the solenoid valve opens and closes. The proposed method detects the movement of the plunger as it generates a measurable signal on the solenoid that surrounds it. Using this plunger signal, we detected the opening and closing of diaphragm and pinch solenoid valves with a systematic error of less than 2 ms. After this systematic error is subtracted, the trial-to-trial error was below 0.2 ms. © 2009 Elsevier B.V. All rights reserved.
format JOUR
author Auzmendi, J.A.
Moffatt, L.
author_facet Auzmendi, J.A.
Moffatt, L.
author_sort Auzmendi, J.A.
title Increasing the reliability of solution exchanges by monitoring solenoid valve actuation
title_short Increasing the reliability of solution exchanges by monitoring solenoid valve actuation
title_full Increasing the reliability of solution exchanges by monitoring solenoid valve actuation
title_fullStr Increasing the reliability of solution exchanges by monitoring solenoid valve actuation
title_full_unstemmed Increasing the reliability of solution exchanges by monitoring solenoid valve actuation
title_sort increasing the reliability of solution exchanges by monitoring solenoid valve actuation
url http://hdl.handle.net/20.500.12110/paper_01650270_v185_n2_p280_Auzmendi
work_keys_str_mv AT auzmendija increasingthereliabilityofsolutionexchangesbymonitoringsolenoidvalveactuation
AT moffattl increasingthereliabilityofsolutionexchangesbymonitoringsolenoidvalveactuation
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