UGA4 gene expression in Saccharomyces cerevisiae depends on cell growth conditions.
In the yeast Saccharomyces cerevisiae, gamma-aminobutyric acid (GABA) transport is mediated by three permeases: the general amino acid permease GAP1, the proline permease PUT4 and the specific GABA permease UGA4. Expression of UGA4 gene is induced in the presence of GABA. We started a comparative st...
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todo:paper_01455680_v44_n4_p585_BermudezMoretti2023-10-03T15:00:02Z UGA4 gene expression in Saccharomyces cerevisiae depends on cell growth conditions. Bermúdez Moretti, M. Correa García, S. Batlle, A. 4 aminobutyric acid 4 aminobutyric acid carrier amino acid transporter carrier protein GABA permease organic anion transporter proline proline transporter Saccharomyces cerevisiae protein UGA4 protein, S cerevisiae article cell division comparative study culture medium drug effect enzymology gene expression regulation genetics growth, development and aging metabolism mutation pH Saccharomyces cerevisiae Amino Acid Transport Systems, Neutral Cell Division Culture Media GABA Plasma Membrane Transport Proteins gamma-Aminobutyric Acid Gene Expression Regulation, Fungal Hydrogen-Ion Concentration Membrane Transport Proteins Mutation Organic Anion Transporters Proline Saccharomyces cerevisiae Saccharomyces cerevisiae Proteins In the yeast Saccharomyces cerevisiae, gamma-aminobutyric acid (GABA) transport is mediated by three permeases: the general amino acid permease GAP1, the proline permease PUT4 and the specific GABA permease UGA4. Expression of UGA4 gene is induced in the presence of GABA. We started a comparative study about UGA4 gene induction in cells grown on different culture media. Results presented here indicate that under certain growth conditions UGA4 permease is constitutive. Therefore, we demonstrate that in S. cerevisiae the UGA4 gene expression depends on cell growth conditions and that its synthesis not always depends on the presence of GABA. Fil:Bermúdez Moretti, M. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Correa García, S. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Batlle, A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_01455680_v44_n4_p585_BermudezMoretti |
institution |
Universidad de Buenos Aires |
institution_str |
I-28 |
repository_str |
R-134 |
collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
topic |
4 aminobutyric acid 4 aminobutyric acid carrier amino acid transporter carrier protein GABA permease organic anion transporter proline proline transporter Saccharomyces cerevisiae protein UGA4 protein, S cerevisiae article cell division comparative study culture medium drug effect enzymology gene expression regulation genetics growth, development and aging metabolism mutation pH Saccharomyces cerevisiae Amino Acid Transport Systems, Neutral Cell Division Culture Media GABA Plasma Membrane Transport Proteins gamma-Aminobutyric Acid Gene Expression Regulation, Fungal Hydrogen-Ion Concentration Membrane Transport Proteins Mutation Organic Anion Transporters Proline Saccharomyces cerevisiae Saccharomyces cerevisiae Proteins |
spellingShingle |
4 aminobutyric acid 4 aminobutyric acid carrier amino acid transporter carrier protein GABA permease organic anion transporter proline proline transporter Saccharomyces cerevisiae protein UGA4 protein, S cerevisiae article cell division comparative study culture medium drug effect enzymology gene expression regulation genetics growth, development and aging metabolism mutation pH Saccharomyces cerevisiae Amino Acid Transport Systems, Neutral Cell Division Culture Media GABA Plasma Membrane Transport Proteins gamma-Aminobutyric Acid Gene Expression Regulation, Fungal Hydrogen-Ion Concentration Membrane Transport Proteins Mutation Organic Anion Transporters Proline Saccharomyces cerevisiae Saccharomyces cerevisiae Proteins Bermúdez Moretti, M. Correa García, S. Batlle, A. UGA4 gene expression in Saccharomyces cerevisiae depends on cell growth conditions. |
topic_facet |
4 aminobutyric acid 4 aminobutyric acid carrier amino acid transporter carrier protein GABA permease organic anion transporter proline proline transporter Saccharomyces cerevisiae protein UGA4 protein, S cerevisiae article cell division comparative study culture medium drug effect enzymology gene expression regulation genetics growth, development and aging metabolism mutation pH Saccharomyces cerevisiae Amino Acid Transport Systems, Neutral Cell Division Culture Media GABA Plasma Membrane Transport Proteins gamma-Aminobutyric Acid Gene Expression Regulation, Fungal Hydrogen-Ion Concentration Membrane Transport Proteins Mutation Organic Anion Transporters Proline Saccharomyces cerevisiae Saccharomyces cerevisiae Proteins |
description |
In the yeast Saccharomyces cerevisiae, gamma-aminobutyric acid (GABA) transport is mediated by three permeases: the general amino acid permease GAP1, the proline permease PUT4 and the specific GABA permease UGA4. Expression of UGA4 gene is induced in the presence of GABA. We started a comparative study about UGA4 gene induction in cells grown on different culture media. Results presented here indicate that under certain growth conditions UGA4 permease is constitutive. Therefore, we demonstrate that in S. cerevisiae the UGA4 gene expression depends on cell growth conditions and that its synthesis not always depends on the presence of GABA. |
format |
JOUR |
author |
Bermúdez Moretti, M. Correa García, S. Batlle, A. |
author_facet |
Bermúdez Moretti, M. Correa García, S. Batlle, A. |
author_sort |
Bermúdez Moretti, M. |
title |
UGA4 gene expression in Saccharomyces cerevisiae depends on cell growth conditions. |
title_short |
UGA4 gene expression in Saccharomyces cerevisiae depends on cell growth conditions. |
title_full |
UGA4 gene expression in Saccharomyces cerevisiae depends on cell growth conditions. |
title_fullStr |
UGA4 gene expression in Saccharomyces cerevisiae depends on cell growth conditions. |
title_full_unstemmed |
UGA4 gene expression in Saccharomyces cerevisiae depends on cell growth conditions. |
title_sort |
uga4 gene expression in saccharomyces cerevisiae depends on cell growth conditions. |
url |
http://hdl.handle.net/20.500.12110/paper_01455680_v44_n4_p585_BermudezMoretti |
work_keys_str_mv |
AT bermudezmorettim uga4geneexpressioninsaccharomycescerevisiaedependsoncellgrowthconditions AT correagarcias uga4geneexpressioninsaccharomycescerevisiaedependsoncellgrowthconditions AT batllea uga4geneexpressioninsaccharomycescerevisiaedependsoncellgrowthconditions |
_version_ |
1807315650359590912 |