Genotypes of pathogenic Leptospira spp isolated from rodents in Argentina
Leptospirosis is the most widespread zoonosis in the world and significant efforts have been made to determine and classify pathogenic Leptospira strains. This zoonosis is maintained in nature through chronic renal infections of carrier animals, with rodents and other small mammals serving as the mo...
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todo:paper_00740276_v109_n2_p163_Loffler2023-10-03T14:53:39Z Genotypes of pathogenic Leptospira spp isolated from rodents in Argentina Loffler, S.G. Pavan, M.E. Vanasco, B. Samartino, L. Suarez, O. Auteri, C. Romero, G. Brihuega, B. Argentina Genotyping Leptospira spp Multiple-locus variable-number tandem repeat analysis Pathogenic Rodent population animal Argentina classification Didelphis genetics genotype genotyping technique isolation and purification Leptospira Leptospira interrogans serovar Canicola Leptospira interrogans serovar Icterohaemorrhagiae Leptospira interrogans serovar Pomona leptospirosis microbiology mouse procedures rat rodent serotype serotyping tandem repeat transmission urban population virulence Animals Argentina Didelphis Genotype Genotyping Techniques Leptospira Leptospira interrogans serovar canicola Leptospira interrogans serovar icterohaemorrhagiae Leptospira interrogans serovar pomona Leptospirosis Mice Rats Rodentia Serogroup Serotyping Tandem Repeat Sequences Urban Population Virulence Leptospirosis is the most widespread zoonosis in the world and significant efforts have been made to determine and classify pathogenic Leptospira strains. This zoonosis is maintained in nature through chronic renal infections of carrier animals, with rodents and other small mammals serving as the most important reservoirs. Additionally, domestic animals, such as livestock and dogs, are significant sources of human infection. In this study, a multiple-locus variable-number tandem repeat analysis (MLVA) was applied to genotype 22 pathogenic Leptospira strains isolated from urban and periurban rodent populations from different regions of Argentina. Three MLVA profiles were identified in strains belonging to the species Leptospira interrogans (serovars Icterohaemorrhagiae and Canicola); one profile was observed in serovar Icterohaemorrhagiae and two MLVA profiles were observed in isolates of serovars Canicola and Portlandvere. All strains belonging to Leptospira borgpetersenii serovar Castellonis exhibited the same MLVA profile. Four different genotypes were isolated from urban populations of rodents, including both mice and rats and two different genotypes were isolated from periurban populations. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_00740276_v109_n2_p163_Loffler |
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Universidad de Buenos Aires |
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I-28 |
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Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
Argentina Genotyping Leptospira spp Multiple-locus variable-number tandem repeat analysis Pathogenic Rodent population animal Argentina classification Didelphis genetics genotype genotyping technique isolation and purification Leptospira Leptospira interrogans serovar Canicola Leptospira interrogans serovar Icterohaemorrhagiae Leptospira interrogans serovar Pomona leptospirosis microbiology mouse procedures rat rodent serotype serotyping tandem repeat transmission urban population virulence Animals Argentina Didelphis Genotype Genotyping Techniques Leptospira Leptospira interrogans serovar canicola Leptospira interrogans serovar icterohaemorrhagiae Leptospira interrogans serovar pomona Leptospirosis Mice Rats Rodentia Serogroup Serotyping Tandem Repeat Sequences Urban Population Virulence |
| spellingShingle |
Argentina Genotyping Leptospira spp Multiple-locus variable-number tandem repeat analysis Pathogenic Rodent population animal Argentina classification Didelphis genetics genotype genotyping technique isolation and purification Leptospira Leptospira interrogans serovar Canicola Leptospira interrogans serovar Icterohaemorrhagiae Leptospira interrogans serovar Pomona leptospirosis microbiology mouse procedures rat rodent serotype serotyping tandem repeat transmission urban population virulence Animals Argentina Didelphis Genotype Genotyping Techniques Leptospira Leptospira interrogans serovar canicola Leptospira interrogans serovar icterohaemorrhagiae Leptospira interrogans serovar pomona Leptospirosis Mice Rats Rodentia Serogroup Serotyping Tandem Repeat Sequences Urban Population Virulence Loffler, S.G. Pavan, M.E. Vanasco, B. Samartino, L. Suarez, O. Auteri, C. Romero, G. Brihuega, B. Genotypes of pathogenic Leptospira spp isolated from rodents in Argentina |
| topic_facet |
Argentina Genotyping Leptospira spp Multiple-locus variable-number tandem repeat analysis Pathogenic Rodent population animal Argentina classification Didelphis genetics genotype genotyping technique isolation and purification Leptospira Leptospira interrogans serovar Canicola Leptospira interrogans serovar Icterohaemorrhagiae Leptospira interrogans serovar Pomona leptospirosis microbiology mouse procedures rat rodent serotype serotyping tandem repeat transmission urban population virulence Animals Argentina Didelphis Genotype Genotyping Techniques Leptospira Leptospira interrogans serovar canicola Leptospira interrogans serovar icterohaemorrhagiae Leptospira interrogans serovar pomona Leptospirosis Mice Rats Rodentia Serogroup Serotyping Tandem Repeat Sequences Urban Population Virulence |
| description |
Leptospirosis is the most widespread zoonosis in the world and significant efforts have been made to determine and classify pathogenic Leptospira strains. This zoonosis is maintained in nature through chronic renal infections of carrier animals, with rodents and other small mammals serving as the most important reservoirs. Additionally, domestic animals, such as livestock and dogs, are significant sources of human infection. In this study, a multiple-locus variable-number tandem repeat analysis (MLVA) was applied to genotype 22 pathogenic Leptospira strains isolated from urban and periurban rodent populations from different regions of Argentina. Three MLVA profiles were identified in strains belonging to the species Leptospira interrogans (serovars Icterohaemorrhagiae and Canicola); one profile was observed in serovar Icterohaemorrhagiae and two MLVA profiles were observed in isolates of serovars Canicola and Portlandvere. All strains belonging to Leptospira borgpetersenii serovar Castellonis exhibited the same MLVA profile. Four different genotypes were isolated from urban populations of rodents, including both mice and rats and two different genotypes were isolated from periurban populations. |
| format |
JOUR |
| author |
Loffler, S.G. Pavan, M.E. Vanasco, B. Samartino, L. Suarez, O. Auteri, C. Romero, G. Brihuega, B. |
| author_facet |
Loffler, S.G. Pavan, M.E. Vanasco, B. Samartino, L. Suarez, O. Auteri, C. Romero, G. Brihuega, B. |
| author_sort |
Loffler, S.G. |
| title |
Genotypes of pathogenic Leptospira spp isolated from rodents in Argentina |
| title_short |
Genotypes of pathogenic Leptospira spp isolated from rodents in Argentina |
| title_full |
Genotypes of pathogenic Leptospira spp isolated from rodents in Argentina |
| title_fullStr |
Genotypes of pathogenic Leptospira spp isolated from rodents in Argentina |
| title_full_unstemmed |
Genotypes of pathogenic Leptospira spp isolated from rodents in Argentina |
| title_sort |
genotypes of pathogenic leptospira spp isolated from rodents in argentina |
| url |
http://hdl.handle.net/20.500.12110/paper_00740276_v109_n2_p163_Loffler |
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