In Vitro and in Vivo effects of tamoxifen against larval stage Echinococcus granulosus

Cystic echinococcosis is a zoonotic infection caused by the larval stage of the cestode Echinococcus granulosus. Chemotherapy currently employs benzimidazoles; however, 40% of cases do not respond favorably. With regard to these difficulties, novel therapeutic tools are needed to optimize treatment...

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Detalles Bibliográficos
Autores principales: Nicolao, M.C., Elissondo, M.C., Denegri, G.M., Goya, A.B., Cumino, A.C.
Formato: JOUR
Materias:
calcium
multidrug resistance protein
placebo
steroid receptor
tamoxifen citrate
tamoxifen
animal experiment
animal model
anthelmintic activity
article
body weight
calcium homeostasis
chemoprophylaxis
concentration (parameters)
controlled study
drug efficacy
echinococcosis
Echinococcus granulosus
female
in vitro study
in vivo study
infection prevention
larval stage
metacestode
mouse
nonhuman
nucleotide sequence
parasite survival
priority journal
weight reduction
animal
antagonists and inhibitors
drug effects
homeostasis
larva
metabolism
Animals
Calcium
Echinococcosis
Female
Homeostasis
Larva
Mice
P-Glycoprotein
Receptors, Steroid
Tamoxifen
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00664804_v58_n9_p5146_Nicolao
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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