Prevalence of Three Prothrombotic Polymorphisms: Factor V G1691A, Factor II G20210A and Methylenetetrahydrofolate Reductase (MTHFR) C 677T in Argentina

Screening in selected but still wide populations such as women with recurrent fetal loss, placental insufficiency, pre-eclampsia, or needing oral contraception, or programmed high-risk surgery in both sexes, is still controversial. Knowledge of the prevalence of these polymorphisms in the general po...

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Detalles Bibliográficos
Autores principales: Genoud, V., Castañon, M., Annichino-Bizzacchi, J., Korin, J., Kordich, L.
Formato: JOUR
Materias:
Factor V Leiden
MTHFR
Prevalence
Prothrombin 20210
Thrombophilia
5,10 methylenetetrahydrofolate reductase (FADH2)
blood clotting factor 5 Leiden
DNA fragment
homocysteine
oral contraceptive agent
phospholipid antibody
protein C
protein S
prothrombin
activated protein C resistance
adult
aged
Argentina
article
blood donor
controlled study
deep vein thrombosis
DNA polymorphism
gene mutation
genetic disorder
genetic variability
heterozygosity
homozygosity
human
human tissue
lung embolism
prevalence
priority journal
risk factor
thromboembolism
thrombophilia
Adult
Aged
Brazil
Factor V
Genetic Screening
Heterozygote
Homozygote
Humans
Methylenetetrahydrofolate Reductase (NADPH2)
Middle Aged
Oxidoreductases Acting on CH-NH Group Donors
Point Mutation
Polymorphism, Genetic
Prothrombin
Risk Factors
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00493848_v100_n3_p127_Genoud
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
Descripción
Sumario:Screening in selected but still wide populations such as women with recurrent fetal loss, placental insufficiency, pre-eclampsia, or needing oral contraception, or programmed high-risk surgery in both sexes, is still controversial. Knowledge of the prevalence of these polymorphisms in the general population is useful in order to take desicions that could considerably increase the burden to health resources, even in developed countries.

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