Cyclic oligomers (macroaldonolactones) from a protected d-galactonic acid monomer
Dicyclohexylcarbodiimide-promoted self-condensation of 2,3:4,5-di-O-isopropylidene-d-galactonic acid (3) led to the macrocyclic oligomeric cyclo[(2,3:4,5-di-O-isopropylidene-(1→6)-d-galactonate)2 ] (4) and cyclo[(2,3:4,5-di-O-isopropylidene-(1→6)-d-galactonate)3 ] (5), having, respectively, 14- and...
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| Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_00404039_v50_n40_p5677_LorenaRomeroZaliz |
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todo:paper_00404039_v50_n40_p5677_LorenaRomeroZaliz2023-10-03T14:50:56Z Cyclic oligomers (macroaldonolactones) from a protected d-galactonic acid monomer Lorena Romero Zaliz, C. Varela, O. Aldonic acid Biomaterial Cyclodextrin Macrocycle Macrolactone 2,3:4,5 di o isopropylidene dextro galactonic acid biomaterial cyclo[(2,3:4,5 di o isopropylidene 2(1-6) dextro galactonate)] cyclo[(2,3:4,5 di o isopropylidene 3(1-6) dextro galactonate)] cyclodextrin galactonic acid lactone derivative macroaldonolactone derivative macrocyclic compound oligomer unclassified drug article cyclization dimerization oligomerization proton nuclear magnetic resonance reaction analysis synthesis Dicyclohexylcarbodiimide-promoted self-condensation of 2,3:4,5-di-O-isopropylidene-d-galactonic acid (3) led to the macrocyclic oligomeric cyclo[(2,3:4,5-di-O-isopropylidene-(1→6)-d-galactonate)2 ] (4) and cyclo[(2,3:4,5-di-O-isopropylidene-(1→6)-d-galactonate)3 ] (5), having, respectively, 14- and 21-membered rings. The macrocycles 4 and 5 were also synthesized by cyclization of the respective linear dimer 11 and trimer 14 ω-hydroxy acids precursors prepared by stepwise additions of 3. Compounds 4 and 5 are biomaterials that may be described as macrolactone-cyclodextrins. © 2009 Elsevier Ltd. All rights reserved. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_00404039_v50_n40_p5677_LorenaRomeroZaliz |
| institution |
Universidad de Buenos Aires |
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I-28 |
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R-134 |
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Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
Aldonic acid Biomaterial Cyclodextrin Macrocycle Macrolactone 2,3:4,5 di o isopropylidene dextro galactonic acid biomaterial cyclo[(2,3:4,5 di o isopropylidene 2(1-6) dextro galactonate)] cyclo[(2,3:4,5 di o isopropylidene 3(1-6) dextro galactonate)] cyclodextrin galactonic acid lactone derivative macroaldonolactone derivative macrocyclic compound oligomer unclassified drug article cyclization dimerization oligomerization proton nuclear magnetic resonance reaction analysis synthesis |
| spellingShingle |
Aldonic acid Biomaterial Cyclodextrin Macrocycle Macrolactone 2,3:4,5 di o isopropylidene dextro galactonic acid biomaterial cyclo[(2,3:4,5 di o isopropylidene 2(1-6) dextro galactonate)] cyclo[(2,3:4,5 di o isopropylidene 3(1-6) dextro galactonate)] cyclodextrin galactonic acid lactone derivative macroaldonolactone derivative macrocyclic compound oligomer unclassified drug article cyclization dimerization oligomerization proton nuclear magnetic resonance reaction analysis synthesis Lorena Romero Zaliz, C. Varela, O. Cyclic oligomers (macroaldonolactones) from a protected d-galactonic acid monomer |
| topic_facet |
Aldonic acid Biomaterial Cyclodextrin Macrocycle Macrolactone 2,3:4,5 di o isopropylidene dextro galactonic acid biomaterial cyclo[(2,3:4,5 di o isopropylidene 2(1-6) dextro galactonate)] cyclo[(2,3:4,5 di o isopropylidene 3(1-6) dextro galactonate)] cyclodextrin galactonic acid lactone derivative macroaldonolactone derivative macrocyclic compound oligomer unclassified drug article cyclization dimerization oligomerization proton nuclear magnetic resonance reaction analysis synthesis |
| description |
Dicyclohexylcarbodiimide-promoted self-condensation of 2,3:4,5-di-O-isopropylidene-d-galactonic acid (3) led to the macrocyclic oligomeric cyclo[(2,3:4,5-di-O-isopropylidene-(1→6)-d-galactonate)2 ] (4) and cyclo[(2,3:4,5-di-O-isopropylidene-(1→6)-d-galactonate)3 ] (5), having, respectively, 14- and 21-membered rings. The macrocycles 4 and 5 were also synthesized by cyclization of the respective linear dimer 11 and trimer 14 ω-hydroxy acids precursors prepared by stepwise additions of 3. Compounds 4 and 5 are biomaterials that may be described as macrolactone-cyclodextrins. © 2009 Elsevier Ltd. All rights reserved. |
| format |
JOUR |
| author |
Lorena Romero Zaliz, C. Varela, O. |
| author_facet |
Lorena Romero Zaliz, C. Varela, O. |
| author_sort |
Lorena Romero Zaliz, C. |
| title |
Cyclic oligomers (macroaldonolactones) from a protected d-galactonic acid monomer |
| title_short |
Cyclic oligomers (macroaldonolactones) from a protected d-galactonic acid monomer |
| title_full |
Cyclic oligomers (macroaldonolactones) from a protected d-galactonic acid monomer |
| title_fullStr |
Cyclic oligomers (macroaldonolactones) from a protected d-galactonic acid monomer |
| title_full_unstemmed |
Cyclic oligomers (macroaldonolactones) from a protected d-galactonic acid monomer |
| title_sort |
cyclic oligomers (macroaldonolactones) from a protected d-galactonic acid monomer |
| url |
http://hdl.handle.net/20.500.12110/paper_00404039_v50_n40_p5677_LorenaRomeroZaliz |
| work_keys_str_mv |
AT lorenaromerozalizc cyclicoligomersmacroaldonolactonesfromaprotecteddgalactonicacidmonomer AT varelao cyclicoligomersmacroaldonolactonesfromaprotecteddgalactonicacidmonomer |
| _version_ |
1807315646462033920 |