A facile synthesis of 3-glycosyl-5-substituted-2-isoxazoles

The 1,3-dipolar cycloaddition reaction between a 2-deoxy-D-aldose oxime (D-gluco or D-ribo) and an alkyne as dipolarophile (phenylacetylene, 2-propyn-1-o1, 3-chloro-1-propyne, or 3-bromo-1-propyne) is described. The new 3-glycosyl-5-substituted-2-isoxazoles are characterized physically and spectrosc...

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Autores principales: Fascio, M.L., D'Accorso, N.B.
Formato: JOUR
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Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00397911_v31_n12_p1913_Fascio
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spelling todo:paper_00397911_v31_n12_p1913_Fascio2023-10-03T14:49:56Z A facile synthesis of 3-glycosyl-5-substituted-2-isoxazoles Fascio, M.L. D'Accorso, N.B. 2 isoxazole derivative alkyne isoxazole derivative oxime unclassified drug article cyclization drug synthesis reaction analysis spectroscopy stereochemistry The 1,3-dipolar cycloaddition reaction between a 2-deoxy-D-aldose oxime (D-gluco or D-ribo) and an alkyne as dipolarophile (phenylacetylene, 2-propyn-1-o1, 3-chloro-1-propyne, or 3-bromo-1-propyne) is described. The new 3-glycosyl-5-substituted-2-isoxazoles are characterized physically and spectroscopically. Fil:Fascio, M.L. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:D'Accorso, N.B. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_00397911_v31_n12_p1913_Fascio
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic 2 isoxazole derivative
alkyne
isoxazole derivative
oxime
unclassified drug
article
cyclization
drug synthesis
reaction analysis
spectroscopy
stereochemistry
spellingShingle 2 isoxazole derivative
alkyne
isoxazole derivative
oxime
unclassified drug
article
cyclization
drug synthesis
reaction analysis
spectroscopy
stereochemistry
Fascio, M.L.
D'Accorso, N.B.
A facile synthesis of 3-glycosyl-5-substituted-2-isoxazoles
topic_facet 2 isoxazole derivative
alkyne
isoxazole derivative
oxime
unclassified drug
article
cyclization
drug synthesis
reaction analysis
spectroscopy
stereochemistry
description The 1,3-dipolar cycloaddition reaction between a 2-deoxy-D-aldose oxime (D-gluco or D-ribo) and an alkyne as dipolarophile (phenylacetylene, 2-propyn-1-o1, 3-chloro-1-propyne, or 3-bromo-1-propyne) is described. The new 3-glycosyl-5-substituted-2-isoxazoles are characterized physically and spectroscopically.
format JOUR
author Fascio, M.L.
D'Accorso, N.B.
author_facet Fascio, M.L.
D'Accorso, N.B.
author_sort Fascio, M.L.
title A facile synthesis of 3-glycosyl-5-substituted-2-isoxazoles
title_short A facile synthesis of 3-glycosyl-5-substituted-2-isoxazoles
title_full A facile synthesis of 3-glycosyl-5-substituted-2-isoxazoles
title_fullStr A facile synthesis of 3-glycosyl-5-substituted-2-isoxazoles
title_full_unstemmed A facile synthesis of 3-glycosyl-5-substituted-2-isoxazoles
title_sort facile synthesis of 3-glycosyl-5-substituted-2-isoxazoles
url http://hdl.handle.net/20.500.12110/paper_00397911_v31_n12_p1913_Fascio
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