ᵦ-(-4 Chlorophenyl) GABA (Baclofen) Inhibits Prolactin and Thyrotropin Release by Acting on the Rat Brain

Baclofen, a GABA B agonist, inhibits prolactin release due to different kinds of stress. In the present study its effect was evaluated in several endocrine experimental situations to explore the specificity of this effect, as well as the site of action of the drug. Baclofen significantly inhibited p...

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Detalles Bibliográficos
Autores principales: Lux, V.A.R., Somoza, G.M., Libertun, C.
Formato: JOUR
Materias:
4 aminobutyric acid b receptor
4 aminobutyric acid receptor
baclofen
dopamine
prolactin
thyrotropin
animal experiment
brain
central nervous system
drug mechanism
drug monitoring
drug receptor binding
endocrine system
hormone release
hypophysis
intraperitoneal drug administration
median eminence
nonhuman
preliminary communication
priority journal
rat
Animal
Animals, Suckling
Baclofen
Brain
Female
Luteinizing Hormone
Male
Median Eminence
Physical Stimulation
Pituitary Gland
Prolactin
Rats
Rats, Inbred Strains
Thyrotropin
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00379727_v183_n3_p358_Lux
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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