Cellular and molecular specificity of pituitary gland physiology
The anterior pituitary gland has the ability to respond to complex signals derived from central and peripheral systems. Perception of these signals and their integration are mediated by cell interactions and cross-talk of multiple signaling transduction pathways and transcriptional regulatory networ...
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| Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_00319333_v92_n1_p1_PerezCastro |
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todo:paper_00319333_v92_n1_p1_PerezCastro2023-10-03T14:43:40Z Cellular and molecular specificity of pituitary gland physiology Perez-Castro, C. Renner, U. Haedo, M.R. Stalla, G.K. Arzt, E. activin bone morphogenetic protein dopamine receptor stimulating agent epidermal growth factor receptor estradiol gonadotropin Notch receptor prolactin retinoid transcription factor Sox transforming growth factor beta ACTH secreting cell adenohypophysis adenoma article breast cancer cell communication cell growth cell interaction cell specificity cell type endocrine cell endothelium cell growth regulation homeostasis hormone release human hypophysis hypophysis cell hypophysis tumor lung cancer microglia molecular biology negative feedback neovascularization (pathology) neurohypophysis nonhuman oncogene paracrine signaling perception peripheral nervous system plasmacytoid dendritic cell positive feedback priority journal prolactin secreting cell prolactinoma protein expression regulatory mechanism senescence TSH secreting cell The anterior pituitary gland has the ability to respond to complex signals derived from central and peripheral systems. Perception of these signals and their integration are mediated by cell interactions and cross-talk of multiple signaling transduction pathways and transcriptional regulatory networks that cooperate for hormone secretion, cell plasticity, and ultimately specific pituitary responses that are essential for an appropriate physiological response. We discuss the physiopathological and molecular mechanisms related to this integrative regulatory system of the anterior pituitary gland and how it contributes to modulate the gland functions and impacts on body homeostasis. © 2012 by the American Physiological Society. Fil:Perez-Castro, C. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Haedo, M.R. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_00319333_v92_n1_p1_PerezCastro |
| institution |
Universidad de Buenos Aires |
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I-28 |
| repository_str |
R-134 |
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Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
activin bone morphogenetic protein dopamine receptor stimulating agent epidermal growth factor receptor estradiol gonadotropin Notch receptor prolactin retinoid transcription factor Sox transforming growth factor beta ACTH secreting cell adenohypophysis adenoma article breast cancer cell communication cell growth cell interaction cell specificity cell type endocrine cell endothelium cell growth regulation homeostasis hormone release human hypophysis hypophysis cell hypophysis tumor lung cancer microglia molecular biology negative feedback neovascularization (pathology) neurohypophysis nonhuman oncogene paracrine signaling perception peripheral nervous system plasmacytoid dendritic cell positive feedback priority journal prolactin secreting cell prolactinoma protein expression regulatory mechanism senescence TSH secreting cell |
| spellingShingle |
activin bone morphogenetic protein dopamine receptor stimulating agent epidermal growth factor receptor estradiol gonadotropin Notch receptor prolactin retinoid transcription factor Sox transforming growth factor beta ACTH secreting cell adenohypophysis adenoma article breast cancer cell communication cell growth cell interaction cell specificity cell type endocrine cell endothelium cell growth regulation homeostasis hormone release human hypophysis hypophysis cell hypophysis tumor lung cancer microglia molecular biology negative feedback neovascularization (pathology) neurohypophysis nonhuman oncogene paracrine signaling perception peripheral nervous system plasmacytoid dendritic cell positive feedback priority journal prolactin secreting cell prolactinoma protein expression regulatory mechanism senescence TSH secreting cell Perez-Castro, C. Renner, U. Haedo, M.R. Stalla, G.K. Arzt, E. Cellular and molecular specificity of pituitary gland physiology |
| topic_facet |
activin bone morphogenetic protein dopamine receptor stimulating agent epidermal growth factor receptor estradiol gonadotropin Notch receptor prolactin retinoid transcription factor Sox transforming growth factor beta ACTH secreting cell adenohypophysis adenoma article breast cancer cell communication cell growth cell interaction cell specificity cell type endocrine cell endothelium cell growth regulation homeostasis hormone release human hypophysis hypophysis cell hypophysis tumor lung cancer microglia molecular biology negative feedback neovascularization (pathology) neurohypophysis nonhuman oncogene paracrine signaling perception peripheral nervous system plasmacytoid dendritic cell positive feedback priority journal prolactin secreting cell prolactinoma protein expression regulatory mechanism senescence TSH secreting cell |
| description |
The anterior pituitary gland has the ability to respond to complex signals derived from central and peripheral systems. Perception of these signals and their integration are mediated by cell interactions and cross-talk of multiple signaling transduction pathways and transcriptional regulatory networks that cooperate for hormone secretion, cell plasticity, and ultimately specific pituitary responses that are essential for an appropriate physiological response. We discuss the physiopathological and molecular mechanisms related to this integrative regulatory system of the anterior pituitary gland and how it contributes to modulate the gland functions and impacts on body homeostasis. © 2012 by the American Physiological Society. |
| format |
JOUR |
| author |
Perez-Castro, C. Renner, U. Haedo, M.R. Stalla, G.K. Arzt, E. |
| author_facet |
Perez-Castro, C. Renner, U. Haedo, M.R. Stalla, G.K. Arzt, E. |
| author_sort |
Perez-Castro, C. |
| title |
Cellular and molecular specificity of pituitary gland physiology |
| title_short |
Cellular and molecular specificity of pituitary gland physiology |
| title_full |
Cellular and molecular specificity of pituitary gland physiology |
| title_fullStr |
Cellular and molecular specificity of pituitary gland physiology |
| title_full_unstemmed |
Cellular and molecular specificity of pituitary gland physiology |
| title_sort |
cellular and molecular specificity of pituitary gland physiology |
| url |
http://hdl.handle.net/20.500.12110/paper_00319333_v92_n1_p1_PerezCastro |
| work_keys_str_mv |
AT perezcastroc cellularandmolecularspecificityofpituitaryglandphysiology AT renneru cellularandmolecularspecificityofpituitaryglandphysiology AT haedomr cellularandmolecularspecificityofpituitaryglandphysiology AT stallagk cellularandmolecularspecificityofpituitaryglandphysiology AT arzte cellularandmolecularspecificityofpituitaryglandphysiology |
| _version_ |
1807323524792057856 |