Sexual dimorphism in diethylstilbestrol-induced prolactin pituitary tumors in F344 rats

Female F344 rats treated chronically with diethylstilbestrol (DES) develop prolactin (PRL)-producing pituitary tumors. These tumors are larger in female than in male rats. To investigate gender differences in DES-induced pituitary tumor formation, we employed female and male rats and neonatally andr...

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Detalles Bibliográficos
Autores principales: Piroli, G.G., Torres, A., Pietranera, L., Grillo, C.A., Ferrini, M.G., Lux-Lantos, V., Aoki, A., De Nicola, A.F.
Formato: JOUR
Materias:
Fischer rats
Gonadal steroid receptors
Gonadal steroids
Immunocytochemistry
Lactotropes
Pituitary tumors
Prolactin
Sexual dimorphism
androgen
diethylstilbestrol
DNA
estrogen receptor
progesterone receptor
prolactin
steroid receptor
testosterone propionate
animal experiment
animal tissue
article
carcinogenesis
cell hyperplasia
cell population
controlled study
female
hormonal regulation
hypertrophy
hypophysis tumor
male
nonhuman
priority journal
prolactin blood level
rat
sex difference
tumor growth
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00283835_v72_n2_p80_Piroli
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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