Regulation of eosinophilia and allergic airway inflammation by the glycan-binding protein galectin-1

Galectin-1 (Gal-1), a glycan-binding protein with broad antiinflammatory activities, functions as a proresolving mediator in autoimmune and chronic inflammatory disorders. However, its role in allergic airway inflammation has not yet been elucidated. We evaluated the effects of Gal-1 on eosinophil f...

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Detalles Bibliográficos
Autores principales: Ge, X.N., Ha, S.G., Greenberg, Y.G., Rao, A., Bastan, I., Blidner, A.G., Rao, S.P., Rabinovich, G.A., Sriramarao, P.
Formato: JOUR
Materias:
Allergic airway inflammation
Apoptosis
Eosinophils
Galectin-1
Migration
allergen
alpha4 integrin
CD11b antigen
CD18 antigen
cell surface receptor
chemokine receptor CCR3
cytoskeleton protein
eotaxin
eotaxin 2
F actin
galectin 1
glycan
interleukin 13
interleukin 5
L selectin
lymphocyte function associated antigen 1
mitogen activated protein kinase 1
mitogen activated protein kinase 3
transforming growth factor beta
tumor necrosis factor alpha
vascular cell adhesion molecule 1
chemokine
cytokine
allergic asthma
animal cell
animal experiment
animal model
animal tissue
apoptosis
Article
bone marrow cell
CD3+ T lymphocyte
cell adhesion
comparative study
concentration response
controlled study
cytoskeleton
enzyme activation
eosinophil
eosinophilia
extracellular space
immunoregulation
in vitro study
in vivo study
inflammatory cell
leukocyte function
leukocyte migration
lung
migration inhibition
mouse
nonhuman
priority journal
protein expression
protein function
protein localization
protein protein interaction
animal
asthma
C57BL mouse
chemistry
physiology
Animals
Asthma
Cell Adhesion
Chemokines
Cytokines
Eosinophilia
Galectin 1
Lung
Mice
Mice, Inbred C57BL
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00278424_v113_n33_pE4837_Ge
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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