Multifocal motor neuropathy. Immediate response to intravenous immunoglobulin

Multifocal motor neuropathy, a rare insidious immune-mediated disorder, features muscular weakness and atrophy, as well as arreflexia, due to nerve conduction block and is often associated with the presence of anti-GM1antibody. We report a patient with a nine-year history of progressive upper limb w...

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Autores principales: Cammarota, A., Nogues, M., Rivero, A., Garcia, H.
Formato: JOUR
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Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00257680_v61_n4_p441_Cammarota
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spelling todo:paper_00257680_v61_n4_p441_Cammarota2023-10-03T14:36:38Z Multifocal motor neuropathy. Immediate response to intravenous immunoglobulin Cammarota, A. Nogues, M. Rivero, A. Garcia, H. Immunoglobulin Multifocal motor neuropathy immunoglobulin immunoglobulin adult amyotrophic lateral sclerosis article case report clinical feature diagnostic error disease course human male motoneuron motor neuropathy muscle strength nerve block treatment outcome amyotrophic lateral sclerosis differential diagnosis middle aged motor neuron disease nerve conduction Amyotrophic Lateral Sclerosis Diagnosis, Differential Humans Immunoglobulins, Intravenous Male Middle Aged Motor Neuron Disease Neural Conduction Multifocal motor neuropathy, a rare insidious immune-mediated disorder, features muscular weakness and atrophy, as well as arreflexia, due to nerve conduction block and is often associated with the presence of anti-GM1antibody. We report a patient with a nine-year history of progressive upper limb weakness, misdiagnosed as amyotrophic lateral sclerosis, who responded within hours to intravenous immunoglobulin treatment with full recovery of muscle strength. This case highlights the need to search for conduction block in patients with lower motor neuron involvement. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_00257680_v61_n4_p441_Cammarota
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic Immunoglobulin
Multifocal motor neuropathy
immunoglobulin
immunoglobulin
adult
amyotrophic lateral sclerosis
article
case report
clinical feature
diagnostic error
disease course
human
male
motoneuron
motor neuropathy
muscle strength
nerve block
treatment outcome
amyotrophic lateral sclerosis
differential diagnosis
middle aged
motor neuron disease
nerve conduction
Amyotrophic Lateral Sclerosis
Diagnosis, Differential
Humans
Immunoglobulins, Intravenous
Male
Middle Aged
Motor Neuron Disease
Neural Conduction
spellingShingle Immunoglobulin
Multifocal motor neuropathy
immunoglobulin
immunoglobulin
adult
amyotrophic lateral sclerosis
article
case report
clinical feature
diagnostic error
disease course
human
male
motoneuron
motor neuropathy
muscle strength
nerve block
treatment outcome
amyotrophic lateral sclerosis
differential diagnosis
middle aged
motor neuron disease
nerve conduction
Amyotrophic Lateral Sclerosis
Diagnosis, Differential
Humans
Immunoglobulins, Intravenous
Male
Middle Aged
Motor Neuron Disease
Neural Conduction
Cammarota, A.
Nogues, M.
Rivero, A.
Garcia, H.
Multifocal motor neuropathy. Immediate response to intravenous immunoglobulin
topic_facet Immunoglobulin
Multifocal motor neuropathy
immunoglobulin
immunoglobulin
adult
amyotrophic lateral sclerosis
article
case report
clinical feature
diagnostic error
disease course
human
male
motoneuron
motor neuropathy
muscle strength
nerve block
treatment outcome
amyotrophic lateral sclerosis
differential diagnosis
middle aged
motor neuron disease
nerve conduction
Amyotrophic Lateral Sclerosis
Diagnosis, Differential
Humans
Immunoglobulins, Intravenous
Male
Middle Aged
Motor Neuron Disease
Neural Conduction
description Multifocal motor neuropathy, a rare insidious immune-mediated disorder, features muscular weakness and atrophy, as well as arreflexia, due to nerve conduction block and is often associated with the presence of anti-GM1antibody. We report a patient with a nine-year history of progressive upper limb weakness, misdiagnosed as amyotrophic lateral sclerosis, who responded within hours to intravenous immunoglobulin treatment with full recovery of muscle strength. This case highlights the need to search for conduction block in patients with lower motor neuron involvement.
format JOUR
author Cammarota, A.
Nogues, M.
Rivero, A.
Garcia, H.
author_facet Cammarota, A.
Nogues, M.
Rivero, A.
Garcia, H.
author_sort Cammarota, A.
title Multifocal motor neuropathy. Immediate response to intravenous immunoglobulin
title_short Multifocal motor neuropathy. Immediate response to intravenous immunoglobulin
title_full Multifocal motor neuropathy. Immediate response to intravenous immunoglobulin
title_fullStr Multifocal motor neuropathy. Immediate response to intravenous immunoglobulin
title_full_unstemmed Multifocal motor neuropathy. Immediate response to intravenous immunoglobulin
title_sort multifocal motor neuropathy. immediate response to intravenous immunoglobulin
url http://hdl.handle.net/20.500.12110/paper_00257680_v61_n4_p441_Cammarota
work_keys_str_mv AT cammarotaa multifocalmotorneuropathyimmediateresponsetointravenousimmunoglobulin
AT noguesm multifocalmotorneuropathyimmediateresponsetointravenousimmunoglobulin
AT riveroa multifocalmotorneuropathyimmediateresponsetointravenousimmunoglobulin
AT garciah multifocalmotorneuropathyimmediateresponsetointravenousimmunoglobulin
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