Stroke vs. chronic progressive cerebrovascular disease: A magnetic resonance imaging study of symptomatic outpatients
Stroke is the main manifestation of cerebrovascular disease (CVD). Few studies report the insidious and progressive development of CVD. The aim of this study was the characterization of a CVD form without stroke in association with vascular subtypes and risk factors (VRF). From 105 CVD patients, 65...
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todo:paper_0022510X_v203-204_n_p67_Dominguez2023-10-03T14:33:26Z Stroke vs. chronic progressive cerebrovascular disease: A magnetic resonance imaging study of symptomatic outpatients Domínguez, R.O. Marschoff, E.R. Serra, J.A. Gallo, A. Bartolomé, E.L. González, S. D'Abbraccio, G. Bagg, E. Vila, J. Famulari, A.L. Cerebrovascular chronic progressive form Complete infarcts Incomplete white matter lesions MRI Neurological manifestations Silent infarcts Stroke Vascular dementia aged brain infarction cerebrovascular disease clinical feature conference paper controlled study correlation analysis disease association disease course female human major clinical study male nuclear magnetic resonance imaging outpatient priority journal risk assessment risk factor stroke Aged Argentina Cerebrovascular Accident Cerebrovascular Disorders Chronic Disease Disease Progression Female Humans Magnetic Resonance Imaging Male Neuropsychological Tests Prospective Studies Risk Factors Stroke is the main manifestation of cerebrovascular disease (CVD). Few studies report the insidious and progressive development of CVD. The aim of this study was the characterization of a CVD form without stroke in association with vascular subtypes and risk factors (VRF). From 105 CVD patients, 65 had stroke (62%), 13 of them had more than one stroke (20%), and 40 patients had a chronic progressive form (CPF) (38%). Mean evolution times up to maximum neurological deficiency were 1.57±0.94 and 344.25±210.96 days, respectively. Group results significantly associated with VRFs: hypertension (p=0.0046), hyperlipemia (p=0.0046) and atrial fibrillation (p=0.0173); with clinical manifestations: aphasia (p=0.0018), pyramidal syndrome (p=0.0000001) and small vessel disease (SVD) (p=0.0000001); and with MRI: bilateral infarctions (p=0.00009) and incomplete white matter lesions (IWMLs) (p=0.0061). Within the CPF group, dysarthria and complete infarctions were associated (p=0.00036). Most neurological disorders associated with CVD are related to CPF. The significant correlations of SVD, bilateral infarcts, IWMLs, dysarthria, several VRFs and the strong difference in evolution time up to maximum neurological deficiency values characterize CPF as a separate entity within CVD. © 2002 Elsevier Science B.V. All rights reserved. Fil:Marschoff, E.R. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_0022510X_v203-204_n_p67_Dominguez |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
Cerebrovascular chronic progressive form Complete infarcts Incomplete white matter lesions MRI Neurological manifestations Silent infarcts Stroke Vascular dementia aged brain infarction cerebrovascular disease clinical feature conference paper controlled study correlation analysis disease association disease course female human major clinical study male nuclear magnetic resonance imaging outpatient priority journal risk assessment risk factor stroke Aged Argentina Cerebrovascular Accident Cerebrovascular Disorders Chronic Disease Disease Progression Female Humans Magnetic Resonance Imaging Male Neuropsychological Tests Prospective Studies Risk Factors |
| spellingShingle |
Cerebrovascular chronic progressive form Complete infarcts Incomplete white matter lesions MRI Neurological manifestations Silent infarcts Stroke Vascular dementia aged brain infarction cerebrovascular disease clinical feature conference paper controlled study correlation analysis disease association disease course female human major clinical study male nuclear magnetic resonance imaging outpatient priority journal risk assessment risk factor stroke Aged Argentina Cerebrovascular Accident Cerebrovascular Disorders Chronic Disease Disease Progression Female Humans Magnetic Resonance Imaging Male Neuropsychological Tests Prospective Studies Risk Factors Domínguez, R.O. Marschoff, E.R. Serra, J.A. Gallo, A. Bartolomé, E.L. González, S. D'Abbraccio, G. Bagg, E. Vila, J. Famulari, A.L. Stroke vs. chronic progressive cerebrovascular disease: A magnetic resonance imaging study of symptomatic outpatients |
| topic_facet |
Cerebrovascular chronic progressive form Complete infarcts Incomplete white matter lesions MRI Neurological manifestations Silent infarcts Stroke Vascular dementia aged brain infarction cerebrovascular disease clinical feature conference paper controlled study correlation analysis disease association disease course female human major clinical study male nuclear magnetic resonance imaging outpatient priority journal risk assessment risk factor stroke Aged Argentina Cerebrovascular Accident Cerebrovascular Disorders Chronic Disease Disease Progression Female Humans Magnetic Resonance Imaging Male Neuropsychological Tests Prospective Studies Risk Factors |
| description |
Stroke is the main manifestation of cerebrovascular disease (CVD). Few studies report the insidious and progressive development of CVD. The aim of this study was the characterization of a CVD form without stroke in association with vascular subtypes and risk factors (VRF). From 105 CVD patients, 65 had stroke (62%), 13 of them had more than one stroke (20%), and 40 patients had a chronic progressive form (CPF) (38%). Mean evolution times up to maximum neurological deficiency were 1.57±0.94 and 344.25±210.96 days, respectively. Group results significantly associated with VRFs: hypertension (p=0.0046), hyperlipemia (p=0.0046) and atrial fibrillation (p=0.0173); with clinical manifestations: aphasia (p=0.0018), pyramidal syndrome (p=0.0000001) and small vessel disease (SVD) (p=0.0000001); and with MRI: bilateral infarctions (p=0.00009) and incomplete white matter lesions (IWMLs) (p=0.0061). Within the CPF group, dysarthria and complete infarctions were associated (p=0.00036). Most neurological disorders associated with CVD are related to CPF. The significant correlations of SVD, bilateral infarcts, IWMLs, dysarthria, several VRFs and the strong difference in evolution time up to maximum neurological deficiency values characterize CPF as a separate entity within CVD. © 2002 Elsevier Science B.V. All rights reserved. |
| format |
JOUR |
| author |
Domínguez, R.O. Marschoff, E.R. Serra, J.A. Gallo, A. Bartolomé, E.L. González, S. D'Abbraccio, G. Bagg, E. Vila, J. Famulari, A.L. |
| author_facet |
Domínguez, R.O. Marschoff, E.R. Serra, J.A. Gallo, A. Bartolomé, E.L. González, S. D'Abbraccio, G. Bagg, E. Vila, J. Famulari, A.L. |
| author_sort |
Domínguez, R.O. |
| title |
Stroke vs. chronic progressive cerebrovascular disease: A magnetic resonance imaging study of symptomatic outpatients |
| title_short |
Stroke vs. chronic progressive cerebrovascular disease: A magnetic resonance imaging study of symptomatic outpatients |
| title_full |
Stroke vs. chronic progressive cerebrovascular disease: A magnetic resonance imaging study of symptomatic outpatients |
| title_fullStr |
Stroke vs. chronic progressive cerebrovascular disease: A magnetic resonance imaging study of symptomatic outpatients |
| title_full_unstemmed |
Stroke vs. chronic progressive cerebrovascular disease: A magnetic resonance imaging study of symptomatic outpatients |
| title_sort |
stroke vs. chronic progressive cerebrovascular disease: a magnetic resonance imaging study of symptomatic outpatients |
| url |
http://hdl.handle.net/20.500.12110/paper_0022510X_v203-204_n_p67_Dominguez |
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