Less polar forms and derivatives of 18 hydroxy-corticosterone

The formation of various compounds upon reaction of 18 hydroxycorticosterone with neutral and acid-added alcohols as well as with acidic aqueous solutions is described. The time course of their formation in such media has been studied. Some of these compounds have been isolated and tentatively ident...

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Detalles Bibliográficos
Autores principales:	Aragones, A., Gros, E.G., Lantos, C.P., Locascio, G.A.
Formato:	JOUR
Materias:	18 hydroxycorticosterone derivative endocrine system 18-Hydroxycorticosterone Butanols Chemistry Corticosterone Ethanol Hydrochloric Acid Methanol Spectrum Analysis, Mass Water
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_00224731_v9_n2_p175_Aragones
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

id	todo:paper_00224731_v9_n2_p175_Aragones
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spelling	todo:paper_00224731_v9_n2_p175_Aragones2023-10-03T14:33:13Z Less polar forms and derivatives of 18 hydroxy-corticosterone Aragones, A. Gros, E.G. Lantos, C.P. Locascio, G.A. 18 hydroxycorticosterone derivative endocrine system 18-Hydroxycorticosterone Butanols Chemistry Corticosterone Ethanol Hydrochloric Acid Methanol Spectrum Analysis, Mass Water The formation of various compounds upon reaction of 18 hydroxycorticosterone with neutral and acid-added alcohols as well as with acidic aqueous solutions is described. The time course of their formation in such media has been studied. Some of these compounds have been isolated and tentatively identified by paper chromatography employing double isotope techniques and by mass spectrometry. The more polar form has a C-20 hemiketalic structure; the single less polar form obtained upon storage in neutral methanol would be the methylketal at C-20 but the less polar fraction having the same mobility in the Chromatographie system employed, obtained upon reaction with acidic aqueous solutions, seems to be formed by two different dehydration products. © 1978. Fil:Aragones, A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Gros, E.G. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Locascio, G.A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_00224731_v9_n2_p175_Aragones
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	18 hydroxycorticosterone derivative endocrine system 18-Hydroxycorticosterone Butanols Chemistry Corticosterone Ethanol Hydrochloric Acid Methanol Spectrum Analysis, Mass Water
spellingShingle	18 hydroxycorticosterone derivative endocrine system 18-Hydroxycorticosterone Butanols Chemistry Corticosterone Ethanol Hydrochloric Acid Methanol Spectrum Analysis, Mass Water Aragones, A. Gros, E.G. Lantos, C.P. Locascio, G.A. Less polar forms and derivatives of 18 hydroxy-corticosterone
topic_facet	18 hydroxycorticosterone derivative endocrine system 18-Hydroxycorticosterone Butanols Chemistry Corticosterone Ethanol Hydrochloric Acid Methanol Spectrum Analysis, Mass Water
description	The formation of various compounds upon reaction of 18 hydroxycorticosterone with neutral and acid-added alcohols as well as with acidic aqueous solutions is described. The time course of their formation in such media has been studied. Some of these compounds have been isolated and tentatively identified by paper chromatography employing double isotope techniques and by mass spectrometry. The more polar form has a C-20 hemiketalic structure; the single less polar form obtained upon storage in neutral methanol would be the methylketal at C-20 but the less polar fraction having the same mobility in the Chromatographie system employed, obtained upon reaction with acidic aqueous solutions, seems to be formed by two different dehydration products. © 1978.
format	JOUR
author	Aragones, A. Gros, E.G. Lantos, C.P. Locascio, G.A.
author_facet	Aragones, A. Gros, E.G. Lantos, C.P. Locascio, G.A.
author_sort	Aragones, A.
title	Less polar forms and derivatives of 18 hydroxy-corticosterone
title_short	Less polar forms and derivatives of 18 hydroxy-corticosterone
title_full	Less polar forms and derivatives of 18 hydroxy-corticosterone
title_fullStr	Less polar forms and derivatives of 18 hydroxy-corticosterone
title_full_unstemmed	Less polar forms and derivatives of 18 hydroxy-corticosterone
title_sort	less polar forms and derivatives of 18 hydroxy-corticosterone
url	http://hdl.handle.net/20.500.12110/paper_00224731_v9_n2_p175_Aragones
work_keys_str_mv	AT aragonesa lesspolarformsandderivativesof18hydroxycorticosterone AT groseg lesspolarformsandderivativesof18hydroxycorticosterone AT lantoscp lesspolarformsandderivativesof18hydroxycorticosterone AT locascioga lesspolarformsandderivativesof18hydroxycorticosterone
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Less polar forms and derivatives of 18 hydroxy-corticosterone

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