Catatonia in depression: Prevalence, clinical correlates, and validation of a scale
Objectives - To examine the clinical correlates of catatonia in depression, to validate a scale for catatonia, and to assess the validity of the DSM-IV criteria of the catatonic features specifier for mood disorders. Methods - series of 79 consecutive patients with depression and 41 patients with Pa...
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| Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_00223050_v60_n3_p326_Starkstein |
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todo:paper_00223050_v60_n3_p326_Starkstein2023-10-03T14:30:54Z Catatonia in depression: Prevalence, clinical correlates, and validation of a scale Starkstein, S.E. Petracca, G. Tesón, A. Chemerinski, E. Merello, M. Migliorelli, R. Leiguarda, R. Catatonia Depression Dopamine Parkinson's disease apomorphine domperidone adult aged article catatonia cognitive defect comparative study daily life activity depression human major clinical study Parkinson disease prevalence priority journal rating scale Objectives - To examine the clinical correlates of catatonia in depression, to validate a scale for catatonia, and to assess the validity of the DSM-IV criteria of the catatonic features specifier for mood disorders. Methods - series of 79 consecutive patients with depression and 41 patients with Parkinson's disease without depression were examined using the modified Rogers scale (MRS), the Parkinson's disease rating (UPDRS), and the structured clinical interview for DSM-III-R (SCID). Results - Sixteen of the 79 depressed patients (20%) had catatonia. Depressed patients with catatonia had significantly higher scores on the MRS than non-catatonic depressed patients matched for severity of depression, or non-depressed patients with Parkinson's disease matched for severity of motor impairment. Depressed patients with catatonia were older, had a significantly higher frequency of major depression, more severe cognitive impairments, and more severe deficits in activities of daily living than depressed non-catatonic patients. The DSM-IV criteria of catatonia separated catatonic patients from with Parkinson's disease matched for motor impairment, with a specificity of 100%. Catatonic signs did not improve after apomorphine. Conclusions - catatonia is most prevalent among elderly patients with severe depression. The study showed the validity of the MRS for the diagnosis of catatonia in depressed patients, as well as the specificity of the DSM-IV criteria of the catatonic features specifier. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_00223050_v60_n3_p326_Starkstein |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
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R-134 |
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Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
Catatonia Depression Dopamine Parkinson's disease apomorphine domperidone adult aged article catatonia cognitive defect comparative study daily life activity depression human major clinical study Parkinson disease prevalence priority journal rating scale |
| spellingShingle |
Catatonia Depression Dopamine Parkinson's disease apomorphine domperidone adult aged article catatonia cognitive defect comparative study daily life activity depression human major clinical study Parkinson disease prevalence priority journal rating scale Starkstein, S.E. Petracca, G. Tesón, A. Chemerinski, E. Merello, M. Migliorelli, R. Leiguarda, R. Catatonia in depression: Prevalence, clinical correlates, and validation of a scale |
| topic_facet |
Catatonia Depression Dopamine Parkinson's disease apomorphine domperidone adult aged article catatonia cognitive defect comparative study daily life activity depression human major clinical study Parkinson disease prevalence priority journal rating scale |
| description |
Objectives - To examine the clinical correlates of catatonia in depression, to validate a scale for catatonia, and to assess the validity of the DSM-IV criteria of the catatonic features specifier for mood disorders. Methods - series of 79 consecutive patients with depression and 41 patients with Parkinson's disease without depression were examined using the modified Rogers scale (MRS), the Parkinson's disease rating (UPDRS), and the structured clinical interview for DSM-III-R (SCID). Results - Sixteen of the 79 depressed patients (20%) had catatonia. Depressed patients with catatonia had significantly higher scores on the MRS than non-catatonic depressed patients matched for severity of depression, or non-depressed patients with Parkinson's disease matched for severity of motor impairment. Depressed patients with catatonia were older, had a significantly higher frequency of major depression, more severe cognitive impairments, and more severe deficits in activities of daily living than depressed non-catatonic patients. The DSM-IV criteria of catatonia separated catatonic patients from with Parkinson's disease matched for motor impairment, with a specificity of 100%. Catatonic signs did not improve after apomorphine. Conclusions - catatonia is most prevalent among elderly patients with severe depression. The study showed the validity of the MRS for the diagnosis of catatonia in depressed patients, as well as the specificity of the DSM-IV criteria of the catatonic features specifier. |
| format |
JOUR |
| author |
Starkstein, S.E. Petracca, G. Tesón, A. Chemerinski, E. Merello, M. Migliorelli, R. Leiguarda, R. |
| author_facet |
Starkstein, S.E. Petracca, G. Tesón, A. Chemerinski, E. Merello, M. Migliorelli, R. Leiguarda, R. |
| author_sort |
Starkstein, S.E. |
| title |
Catatonia in depression: Prevalence, clinical correlates, and validation of a scale |
| title_short |
Catatonia in depression: Prevalence, clinical correlates, and validation of a scale |
| title_full |
Catatonia in depression: Prevalence, clinical correlates, and validation of a scale |
| title_fullStr |
Catatonia in depression: Prevalence, clinical correlates, and validation of a scale |
| title_full_unstemmed |
Catatonia in depression: Prevalence, clinical correlates, and validation of a scale |
| title_sort |
catatonia in depression: prevalence, clinical correlates, and validation of a scale |
| url |
http://hdl.handle.net/20.500.12110/paper_00223050_v60_n3_p326_Starkstein |
| work_keys_str_mv |
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1807322213848711168 |