Human M2 macrophages limit NK cell effector functions through secretion of TGF-b and engagement of CD85j

NK cells play important roles during immunosurveillance against tumors and viruses as they trigger cytotoxicity against susceptible cells and secrete proinflammatory cytokines such as IFN-g. In addition, upon activation, macrophages can become proinflammatory (M1) or anti-inflammatory (M2) cells. Al...

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Detalles Bibliográficos
Autores principales: Nuñez, S.Y., Ziblat, A., Secchiari, F., Torres, N.I., Sierra, J.M., Raffo Iraolagoitia, X.L., Araya, R.E., Domaica, C.I., Fuertes, M.B., Zwirner, N.W.
Formato: JOUR
Materias:
CD56 antigen
gamma interferon
HLA G antigen
leukocyte antigen
leukocyte immunoglobulin like receptor subfamily B member 1
LILRB1 protein, human
NCAM1 protein, human
transforming growth factor beta
cell communication
cell culture
coculture
human
immunology
lymphocyte activation
macrophage
macrophage activation
metabolism
natural killer cell
secretion (process)
Antigens, CD
CD56 Antigen
Cell Communication
Cells, Cultured
Coculture Techniques
HLA-G Antigens
Humans
Interferon-gamma
Killer Cells, Natural
Leukocyte Immunoglobulin-like Receptor B1
Lymphocyte Activation
Macrophage Activation
Macrophages
Transforming Growth Factor beta
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00221767_v200_n3_p1008_Nunez
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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