Steroid Hormones Induce bcl-X Gene Expression through Direct Activation of Distal Promoter P4

Bcl-X exists in at least five different isoforms with complex effects on programmed cell death. Glucocorticoids and progestins control bcl-X expression and influence the ratio between bcl-XL (antiapoptotic isoform) and bcl-XS (proapoptotic isoform) in different tissues. The 5′-UTR region of the mous...

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Detalles Bibliográficos
Autores principales: Viegas, L.R., Vicent, G.P., Barañao, J.L., Beato, M., Pecci, A.
Formato: JOUR
Materias:
Chemical bonds
Correlation methods
Cytology
Genes
RNA
Tissue
Epithelial cells
Mutants
Hormones
gestagen
glucocorticoid
protein bcl x
steroid hormone
alternative RNA splicing
animal cell
article
cell death
cell type
codon
controlled study
enhancer region
epithelium cell
gene activation
gene expression regulation
gene induction
hormone response
hormone responsive element
nonhuman
point mutation
priority journal
promoter region
protein family
protein protein interaction
tissue specificity
translation initiation
Animals
Apoptosis
Base Sequence
bcl-X Protein
Binding, Competitive
Cell Line
Cell Nucleus
Chromatin
Codon
COS Cells
DNA
Exons
Gene Expression Regulation
Genetic Vectors
Glucocorticoids
Mice
Models, Genetic
Molecular Sequence Data
Open Reading Frames
Plasmids
Point Mutation
Precipitin Tests
Progestins
Promoter Regions (Genetics)
Protein Binding
Protein Biosynthesis
Protein Isoforms
Proto-Oncogene Proteins c-bcl-2
Receptors, Progesterone
Recombinant Proteins
RNA, Messenger
Steroids
Sulfuric Acid Esters
Transfection
Animalia
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00219258_v279_n11_p9831_Viegas
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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