Red blood cell rhodanese: Its possible role in modulating δ-aminolaevulinate synthetase activity in mammals

1. 1. The optimum conditions for measuring rhodanese activity in human erythrocytes were established. The mean control values for males (112 nmol SCN/30 min/mg protein) and females (127 nmol SCN/30 min/mg protein) were determined. 2. 2. Rhodanese activity was measured in different porphyric patients...

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Autores principales: Vazquez, E., Buzaleh, A.M., Wider, E., Del C. Batlle, A.M.
Formato: JOUR
Materias:
5 aminolevulinate synthase
thiosulfate sulfurtransferase
acute intermittent porphyria
blood and hemopoietic system
clinical article
erythrocyte
erythropoietic protoporphyria
human
intoxication
lead poisoning
porphyria cutanea tarda
porphyria variegata
5-Aminolevulinate Synthetase
Erythrocytes
Female
Human
Kinetics
Lead Poisoning
Male
Porphyria
Skin Diseases
Sulfurtransferases
Support, Non-U.S. Gov't
Thiosulfate Sulfurtransferase
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_0020711X_v19_n2_p217_Vazquez
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
id todo:paper_0020711X_v19_n2_p217_Vazquez
record_format dspace
spelling todo:paper_0020711X_v19_n2_p217_Vazquez2023-10-03T14:17:54Z Red blood cell rhodanese: Its possible role in modulating δ-aminolaevulinate synthetase activity in mammals Vazquez, E. Buzaleh, A.M. Wider, E. Del C. Batlle, A.M. 5 aminolevulinate synthase thiosulfate sulfurtransferase acute intermittent porphyria blood and hemopoietic system clinical article erythrocyte erythropoietic protoporphyria human intoxication lead poisoning porphyria cutanea tarda porphyria variegata 5-Aminolevulinate Synthetase Erythrocytes Female Human Kinetics Lead Poisoning Male Porphyria Skin Diseases Sulfurtransferases Support, Non-U.S. Gov't Thiosulfate Sulfurtransferase 1. 1. The optimum conditions for measuring rhodanese activity in human erythrocytes were established. The mean control values for males (112 nmol SCN/30 min/mg protein) and females (127 nmol SCN/30 min/mg protein) were determined. 2. 2. Rhodanese activity was measured in different porphyric patients. The activity was diminished in porphyria cutanea tarda (PCT), acute intermittent porphyria (AIP), variegate porphyria (VP) and lead intoxication (Pb), remaining in erythropoietic protoporphyria (EPP). 3. 3. δ-Aminolaevulinate synthetase (ALA-S) activity was increased in PCT, AIP, VP and Pb showing no changes in EPP. 4. 4. It is suggested that a similar scheme, to that proposed for the control of ALA-S in Rhodopseudomonas spheroides and soybean callus, is also operating in animals. © 1987. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_0020711X_v19_n2_p217_Vazquez
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic 5 aminolevulinate synthase
thiosulfate sulfurtransferase
acute intermittent porphyria
blood and hemopoietic system
clinical article
erythrocyte
erythropoietic protoporphyria
human
intoxication
lead poisoning
porphyria cutanea tarda
porphyria variegata
5-Aminolevulinate Synthetase
Erythrocytes
Female
Human
Kinetics
Lead Poisoning
Male
Porphyria
Skin Diseases
Sulfurtransferases
Support, Non-U.S. Gov't
Thiosulfate Sulfurtransferase
spellingShingle 5 aminolevulinate synthase
thiosulfate sulfurtransferase
acute intermittent porphyria
blood and hemopoietic system
clinical article
erythrocyte
erythropoietic protoporphyria
human
intoxication
lead poisoning
porphyria cutanea tarda
porphyria variegata
5-Aminolevulinate Synthetase
Erythrocytes
Female
Human
Kinetics
Lead Poisoning
Male
Porphyria
Skin Diseases
Sulfurtransferases
Support, Non-U.S. Gov't
Thiosulfate Sulfurtransferase
Vazquez, E.
Buzaleh, A.M.
Wider, E.
Del C. Batlle, A.M.
Red blood cell rhodanese: Its possible role in modulating δ-aminolaevulinate synthetase activity in mammals
topic_facet 5 aminolevulinate synthase
thiosulfate sulfurtransferase
acute intermittent porphyria
blood and hemopoietic system
clinical article
erythrocyte
erythropoietic protoporphyria
human
intoxication
lead poisoning
porphyria cutanea tarda
porphyria variegata
5-Aminolevulinate Synthetase
Erythrocytes
Female
Human
Kinetics
Lead Poisoning
Male
Porphyria
Skin Diseases
Sulfurtransferases
Support, Non-U.S. Gov't
Thiosulfate Sulfurtransferase
description 1. 1. The optimum conditions for measuring rhodanese activity in human erythrocytes were established. The mean control values for males (112 nmol SCN/30 min/mg protein) and females (127 nmol SCN/30 min/mg protein) were determined. 2. 2. Rhodanese activity was measured in different porphyric patients. The activity was diminished in porphyria cutanea tarda (PCT), acute intermittent porphyria (AIP), variegate porphyria (VP) and lead intoxication (Pb), remaining in erythropoietic protoporphyria (EPP). 3. 3. δ-Aminolaevulinate synthetase (ALA-S) activity was increased in PCT, AIP, VP and Pb showing no changes in EPP. 4. 4. It is suggested that a similar scheme, to that proposed for the control of ALA-S in Rhodopseudomonas spheroides and soybean callus, is also operating in animals. © 1987.
format JOUR
author Vazquez, E.
Buzaleh, A.M.
Wider, E.
Del C. Batlle, A.M.
author_facet Vazquez, E.
Buzaleh, A.M.
Wider, E.
Del C. Batlle, A.M.
author_sort Vazquez, E.
title Red blood cell rhodanese: Its possible role in modulating δ-aminolaevulinate synthetase activity in mammals
title_short Red blood cell rhodanese: Its possible role in modulating δ-aminolaevulinate synthetase activity in mammals
title_full Red blood cell rhodanese: Its possible role in modulating δ-aminolaevulinate synthetase activity in mammals
title_fullStr Red blood cell rhodanese: Its possible role in modulating δ-aminolaevulinate synthetase activity in mammals
title_full_unstemmed Red blood cell rhodanese: Its possible role in modulating δ-aminolaevulinate synthetase activity in mammals
title_sort red blood cell rhodanese: its possible role in modulating δ-aminolaevulinate synthetase activity in mammals
url http://hdl.handle.net/20.500.12110/paper_0020711X_v19_n2_p217_Vazquez
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AT widere redbloodcellrhodaneseitspossibleroleinmodulatingdaminolaevulinatesynthetaseactivityinmammals
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