Some factors affecting glomerulopressin production by perfused rat liver

Studies were carried out on the production of the glucuronide hormone glomerulopressin by the isolated rat liver in male and female rats, and the effect on this production of an inhibitor (Novobiocin) and a stimulator (benzo-(a)pyrene) of glucuronyltransferase activity. It was observed that males pr...

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Autores principales: Arany, E., Del Castillo, E., Uranga, J.
Formato: JOUR
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Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00185043_v14_n12_p667_Arany
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spelling todo:paper_00185043_v14_n12_p667_Arany2023-10-03T14:15:35Z Some factors affecting glomerulopressin production by perfused rat liver Arany, E. Del Castillo, E. Uranga, J. benzo[a]pyrene glomerulopressin glucuronide glucuronosyltransferase novobiocin testosterone propionate unclassified drug animal experiment article drug efficacy enzyme activation liver nonhuman sex difference Animalia Studies were carried out on the production of the glucuronide hormone glomerulopressin by the isolated rat liver in male and female rats, and the effect on this production of an inhibitor (Novobiocin) and a stimulator (benzo-(a)pyrene) of glucuronyltransferase activity. It was observed that males produce more glomerulopressin than females, Novobiocin inhibits its production while benzo(a)pyrene enhances it in females but not in males. The changes in glomerulopressin production are related to the changes in glucuronyltransferase activity observed by other authors, suggesting that this enzyme is involved in the production of glomerulopressin. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_00185043_v14_n12_p667_Arany
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic benzo[a]pyrene
glomerulopressin
glucuronide
glucuronosyltransferase
novobiocin
testosterone propionate
unclassified drug
animal experiment
article
drug efficacy
enzyme activation
liver
nonhuman
sex difference
Animalia
spellingShingle benzo[a]pyrene
glomerulopressin
glucuronide
glucuronosyltransferase
novobiocin
testosterone propionate
unclassified drug
animal experiment
article
drug efficacy
enzyme activation
liver
nonhuman
sex difference
Animalia
Arany, E.
Del Castillo, E.
Uranga, J.
Some factors affecting glomerulopressin production by perfused rat liver
topic_facet benzo[a]pyrene
glomerulopressin
glucuronide
glucuronosyltransferase
novobiocin
testosterone propionate
unclassified drug
animal experiment
article
drug efficacy
enzyme activation
liver
nonhuman
sex difference
Animalia
description Studies were carried out on the production of the glucuronide hormone glomerulopressin by the isolated rat liver in male and female rats, and the effect on this production of an inhibitor (Novobiocin) and a stimulator (benzo-(a)pyrene) of glucuronyltransferase activity. It was observed that males produce more glomerulopressin than females, Novobiocin inhibits its production while benzo(a)pyrene enhances it in females but not in males. The changes in glomerulopressin production are related to the changes in glucuronyltransferase activity observed by other authors, suggesting that this enzyme is involved in the production of glomerulopressin.
format JOUR
author Arany, E.
Del Castillo, E.
Uranga, J.
author_facet Arany, E.
Del Castillo, E.
Uranga, J.
author_sort Arany, E.
title Some factors affecting glomerulopressin production by perfused rat liver
title_short Some factors affecting glomerulopressin production by perfused rat liver
title_full Some factors affecting glomerulopressin production by perfused rat liver
title_fullStr Some factors affecting glomerulopressin production by perfused rat liver
title_full_unstemmed Some factors affecting glomerulopressin production by perfused rat liver
title_sort some factors affecting glomerulopressin production by perfused rat liver
url http://hdl.handle.net/20.500.12110/paper_00185043_v14_n12_p667_Arany
work_keys_str_mv AT aranye somefactorsaffectingglomerulopressinproductionbyperfusedratliver
AT delcastilloe somefactorsaffectingglomerulopressinproductionbyperfusedratliver
AT urangaj somefactorsaffectingglomerulopressinproductionbyperfusedratliver
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