An antiviral factor from Melia azedarach L. prevents Tacaribe virus encephalitis in mice
Treatment of neonatal mice with an antiviral factor, (AVF), obtained from the leaves of Melia azederach L. protected them against lethal encephalitis caused by Tacaribe virus inoculation. The degree of protection obtained varied from 66% to 100% depending on the virus dose. Similarly, administration...
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| Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_00144754_v42_n7_p843_Andrei |
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todo:paper_00144754_v42_n7_p843_Andrei2023-10-03T14:12:33Z An antiviral factor from Melia azedarach L. prevents Tacaribe virus encephalitis in mice Andrei, G.M. Lampuri, J.S. Coto, C.E. de Torres, R.A. Antiviral activity arenavirus Melia azedarach L Tacaribe virus viral encephalitis antivirus agent central nervous system experimental infection higher plant mouse nonhuman priority journal tacaribe arenavirus therapy virus encephalitis Animal Animals, Newborn Antiviral Agents Arenaviruses, New World Encephalitis Female Hemorrhagic Fever, American Lactation Mice Plant Extracts Pregnancy Support, Non-U.S. Gov't Virus Replication Treatment of neonatal mice with an antiviral factor, (AVF), obtained from the leaves of Melia azederach L. protected them against lethal encephalitis caused by Tacaribe virus inoculation. The degree of protection obtained varied from 66% to 100% depending on the virus dose. Similarly, administration of AVF to nursing mothers protected their offspring from developing virus encephalitis. AVF does not directly inactivate Tacaribe virus; it inhibits an early step (s) in the replication process in cell cultures. © 1986 Birkhäuser Verlag Basel. Fil:Andrei, G.M. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Lampuri, J.S. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Coto, C.E. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_00144754_v42_n7_p843_Andrei |
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Universidad de Buenos Aires |
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I-28 |
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R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
Antiviral activity arenavirus Melia azedarach L Tacaribe virus viral encephalitis antivirus agent central nervous system experimental infection higher plant mouse nonhuman priority journal tacaribe arenavirus therapy virus encephalitis Animal Animals, Newborn Antiviral Agents Arenaviruses, New World Encephalitis Female Hemorrhagic Fever, American Lactation Mice Plant Extracts Pregnancy Support, Non-U.S. Gov't Virus Replication |
| spellingShingle |
Antiviral activity arenavirus Melia azedarach L Tacaribe virus viral encephalitis antivirus agent central nervous system experimental infection higher plant mouse nonhuman priority journal tacaribe arenavirus therapy virus encephalitis Animal Animals, Newborn Antiviral Agents Arenaviruses, New World Encephalitis Female Hemorrhagic Fever, American Lactation Mice Plant Extracts Pregnancy Support, Non-U.S. Gov't Virus Replication Andrei, G.M. Lampuri, J.S. Coto, C.E. de Torres, R.A. An antiviral factor from Melia azedarach L. prevents Tacaribe virus encephalitis in mice |
| topic_facet |
Antiviral activity arenavirus Melia azedarach L Tacaribe virus viral encephalitis antivirus agent central nervous system experimental infection higher plant mouse nonhuman priority journal tacaribe arenavirus therapy virus encephalitis Animal Animals, Newborn Antiviral Agents Arenaviruses, New World Encephalitis Female Hemorrhagic Fever, American Lactation Mice Plant Extracts Pregnancy Support, Non-U.S. Gov't Virus Replication |
| description |
Treatment of neonatal mice with an antiviral factor, (AVF), obtained from the leaves of Melia azederach L. protected them against lethal encephalitis caused by Tacaribe virus inoculation. The degree of protection obtained varied from 66% to 100% depending on the virus dose. Similarly, administration of AVF to nursing mothers protected their offspring from developing virus encephalitis. AVF does not directly inactivate Tacaribe virus; it inhibits an early step (s) in the replication process in cell cultures. © 1986 Birkhäuser Verlag Basel. |
| format |
JOUR |
| author |
Andrei, G.M. Lampuri, J.S. Coto, C.E. de Torres, R.A. |
| author_facet |
Andrei, G.M. Lampuri, J.S. Coto, C.E. de Torres, R.A. |
| author_sort |
Andrei, G.M. |
| title |
An antiviral factor from Melia azedarach L. prevents Tacaribe virus encephalitis in mice |
| title_short |
An antiviral factor from Melia azedarach L. prevents Tacaribe virus encephalitis in mice |
| title_full |
An antiviral factor from Melia azedarach L. prevents Tacaribe virus encephalitis in mice |
| title_fullStr |
An antiviral factor from Melia azedarach L. prevents Tacaribe virus encephalitis in mice |
| title_full_unstemmed |
An antiviral factor from Melia azedarach L. prevents Tacaribe virus encephalitis in mice |
| title_sort |
antiviral factor from melia azedarach l. prevents tacaribe virus encephalitis in mice |
| url |
http://hdl.handle.net/20.500.12110/paper_00144754_v42_n7_p843_Andrei |
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