Transfer of oligosaccharide from oligosaccharide pyrophosphoryl dolichol to endogenous acceptor proteins in human breast malignant and normal tissues
We have prepared dolichylpyrophosphoryl-[14C]-oligosaccharide (Dol-PP-oligosaccharide) from calf thyroid. Microsomal fractions from human breast tissues catalyzed the transfer of labeled oligosaccharide to endogenous acceptor proteins. Malignant tumors showed higher activity of the oligosaccharide t...
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| Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_00144754_v41_n7_p928_SantaCruz |
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todo:paper_00144754_v41_n7_p928_SantaCruz2023-10-03T14:12:32Z Transfer of oligosaccharide from oligosaccharide pyrophosphoryl dolichol to endogenous acceptor proteins in human breast malignant and normal tissues Santa Cruz, A.R. Baldi, A. human breast cancer glycoproteins kojibiose Oligosaccharide transfer glycoprotein radioisotope animal cell breast breast cancer cattle cow diagnosis endocrine system human human cell kojibiose nonhuman oligosaccharide transfer priority journal thyroid gland Animal Breast Breast Neoplasms Cattle Disaccharides Female Glycoproteins Human Microsomes Oligosaccharides Polyisoprenyl Phosphate Sugars Protein Processing, Post-Translational We have prepared dolichylpyrophosphoryl-[14C]-oligosaccharide (Dol-PP-oligosaccharide) from calf thyroid. Microsomal fractions from human breast tissues catalyzed the transfer of labeled oligosaccharide to endogenous acceptor proteins. Malignant tumors showed higher activity of the oligosaccharide transferring enzyme than normal tissue. With kojibiose (Kj), and inhibitor of (Glc3)-glucosidase, an increase in the radioactivity associated with glycoprotein was observed. © 1985 Birkhäuser Verlag. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_00144754_v41_n7_p928_SantaCruz |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
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Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
human breast cancer glycoproteins kojibiose Oligosaccharide transfer glycoprotein radioisotope animal cell breast breast cancer cattle cow diagnosis endocrine system human human cell kojibiose nonhuman oligosaccharide transfer priority journal thyroid gland Animal Breast Breast Neoplasms Cattle Disaccharides Female Glycoproteins Human Microsomes Oligosaccharides Polyisoprenyl Phosphate Sugars Protein Processing, Post-Translational |
| spellingShingle |
human breast cancer glycoproteins kojibiose Oligosaccharide transfer glycoprotein radioisotope animal cell breast breast cancer cattle cow diagnosis endocrine system human human cell kojibiose nonhuman oligosaccharide transfer priority journal thyroid gland Animal Breast Breast Neoplasms Cattle Disaccharides Female Glycoproteins Human Microsomes Oligosaccharides Polyisoprenyl Phosphate Sugars Protein Processing, Post-Translational Santa Cruz, A.R. Baldi, A. Transfer of oligosaccharide from oligosaccharide pyrophosphoryl dolichol to endogenous acceptor proteins in human breast malignant and normal tissues |
| topic_facet |
human breast cancer glycoproteins kojibiose Oligosaccharide transfer glycoprotein radioisotope animal cell breast breast cancer cattle cow diagnosis endocrine system human human cell kojibiose nonhuman oligosaccharide transfer priority journal thyroid gland Animal Breast Breast Neoplasms Cattle Disaccharides Female Glycoproteins Human Microsomes Oligosaccharides Polyisoprenyl Phosphate Sugars Protein Processing, Post-Translational |
| description |
We have prepared dolichylpyrophosphoryl-[14C]-oligosaccharide (Dol-PP-oligosaccharide) from calf thyroid. Microsomal fractions from human breast tissues catalyzed the transfer of labeled oligosaccharide to endogenous acceptor proteins. Malignant tumors showed higher activity of the oligosaccharide transferring enzyme than normal tissue. With kojibiose (Kj), and inhibitor of (Glc3)-glucosidase, an increase in the radioactivity associated with glycoprotein was observed. © 1985 Birkhäuser Verlag. |
| format |
JOUR |
| author |
Santa Cruz, A.R. Baldi, A. |
| author_facet |
Santa Cruz, A.R. Baldi, A. |
| author_sort |
Santa Cruz, A.R. |
| title |
Transfer of oligosaccharide from oligosaccharide pyrophosphoryl dolichol to endogenous acceptor proteins in human breast malignant and normal tissues |
| title_short |
Transfer of oligosaccharide from oligosaccharide pyrophosphoryl dolichol to endogenous acceptor proteins in human breast malignant and normal tissues |
| title_full |
Transfer of oligosaccharide from oligosaccharide pyrophosphoryl dolichol to endogenous acceptor proteins in human breast malignant and normal tissues |
| title_fullStr |
Transfer of oligosaccharide from oligosaccharide pyrophosphoryl dolichol to endogenous acceptor proteins in human breast malignant and normal tissues |
| title_full_unstemmed |
Transfer of oligosaccharide from oligosaccharide pyrophosphoryl dolichol to endogenous acceptor proteins in human breast malignant and normal tissues |
| title_sort |
transfer of oligosaccharide from oligosaccharide pyrophosphoryl dolichol to endogenous acceptor proteins in human breast malignant and normal tissues |
| url |
http://hdl.handle.net/20.500.12110/paper_00144754_v41_n7_p928_SantaCruz |
| work_keys_str_mv |
AT santacruzar transferofoligosaccharidefromoligosaccharidepyrophosphoryldolicholtoendogenousacceptorproteinsinhumanbreastmalignantandnormaltissues AT baldia transferofoligosaccharidefromoligosaccharidepyrophosphoryldolicholtoendogenousacceptorproteinsinhumanbreastmalignantandnormaltissues |
| _version_ |
1782030694728335360 |