Is prostacyclin subserving a vasodilator effect of methoxamine involving alpha adrenoreceptors?

The influence of methoxamine on the contractile tension of isolated rat abdominal aorta, and on its capacity to produce a platelet antiaggregating substance, were explored. Methoxamine stimulated platelet antiaggregation and diminished arterial tone. The last action was blocked by phentolamine as we...

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Autores principales: Borda, E., Sterin-Borda, L., Gimeno, M.F., Lazzari, M., Gimeno, A.L.
Formato: JOUR
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Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00144754_v39_n8_p894_Borda
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spelling todo:paper_00144754_v39_n8_p894_Borda2023-10-03T14:12:29Z Is prostacyclin subserving a vasodilator effect of methoxamine involving alpha adrenoreceptors? Borda, E. Sterin-Borda, L. Gimeno, M.F. Lazzari, M. Gimeno, A.L. 4 aminophenol acetylsalicylic acid alpha adrenergic receptor indometacin methoxamine phentolamine propranolol prostacyclin prostacyclin synthase tranylcypromine animal cell ant aorta drug efficacy great blood vessel nonhuman rat Animals Aorta, Abdominal Epoprostenol Indomethacin Male Methoxamine Muscle Contraction Platelet Aggregation Prostaglandins Rats Rats, Inbred Strains Receptors, Adrenergic Receptors, Adrenergic, alpha Vasodilator Agents Animalia Formicidae The influence of methoxamine on the contractile tension of isolated rat abdominal aorta, and on its capacity to produce a platelet antiaggregating substance, were explored. Methoxamine stimulated platelet antiaggregation and diminished arterial tone. The last action was blocked by phentolamine as well as by inhibitiors of cyclo-oxygenase and prostacyclinsynthetase. © 1983 Birkhäuser Verlag. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_00144754_v39_n8_p894_Borda
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic 4 aminophenol
acetylsalicylic acid
alpha adrenergic receptor
indometacin
methoxamine
phentolamine
propranolol
prostacyclin
prostacyclin synthase
tranylcypromine
animal cell
ant
aorta
drug efficacy
great blood vessel
nonhuman
rat
Animals
Aorta, Abdominal
Epoprostenol
Indomethacin
Male
Methoxamine
Muscle Contraction
Platelet Aggregation
Prostaglandins
Rats
Rats, Inbred Strains
Receptors, Adrenergic
Receptors, Adrenergic, alpha
Vasodilator Agents
Animalia
Formicidae
spellingShingle 4 aminophenol
acetylsalicylic acid
alpha adrenergic receptor
indometacin
methoxamine
phentolamine
propranolol
prostacyclin
prostacyclin synthase
tranylcypromine
animal cell
ant
aorta
drug efficacy
great blood vessel
nonhuman
rat
Animals
Aorta, Abdominal
Epoprostenol
Indomethacin
Male
Methoxamine
Muscle Contraction
Platelet Aggregation
Prostaglandins
Rats
Rats, Inbred Strains
Receptors, Adrenergic
Receptors, Adrenergic, alpha
Vasodilator Agents
Animalia
Formicidae
Borda, E.
Sterin-Borda, L.
Gimeno, M.F.
Lazzari, M.
Gimeno, A.L.
Is prostacyclin subserving a vasodilator effect of methoxamine involving alpha adrenoreceptors?
topic_facet 4 aminophenol
acetylsalicylic acid
alpha adrenergic receptor
indometacin
methoxamine
phentolamine
propranolol
prostacyclin
prostacyclin synthase
tranylcypromine
animal cell
ant
aorta
drug efficacy
great blood vessel
nonhuman
rat
Animals
Aorta, Abdominal
Epoprostenol
Indomethacin
Male
Methoxamine
Muscle Contraction
Platelet Aggregation
Prostaglandins
Rats
Rats, Inbred Strains
Receptors, Adrenergic
Receptors, Adrenergic, alpha
Vasodilator Agents
Animalia
Formicidae
description The influence of methoxamine on the contractile tension of isolated rat abdominal aorta, and on its capacity to produce a platelet antiaggregating substance, were explored. Methoxamine stimulated platelet antiaggregation and diminished arterial tone. The last action was blocked by phentolamine as well as by inhibitiors of cyclo-oxygenase and prostacyclinsynthetase. © 1983 Birkhäuser Verlag.
format JOUR
author Borda, E.
Sterin-Borda, L.
Gimeno, M.F.
Lazzari, M.
Gimeno, A.L.
author_facet Borda, E.
Sterin-Borda, L.
Gimeno, M.F.
Lazzari, M.
Gimeno, A.L.
author_sort Borda, E.
title Is prostacyclin subserving a vasodilator effect of methoxamine involving alpha adrenoreceptors?
title_short Is prostacyclin subserving a vasodilator effect of methoxamine involving alpha adrenoreceptors?
title_full Is prostacyclin subserving a vasodilator effect of methoxamine involving alpha adrenoreceptors?
title_fullStr Is prostacyclin subserving a vasodilator effect of methoxamine involving alpha adrenoreceptors?
title_full_unstemmed Is prostacyclin subserving a vasodilator effect of methoxamine involving alpha adrenoreceptors?
title_sort is prostacyclin subserving a vasodilator effect of methoxamine involving alpha adrenoreceptors?
url http://hdl.handle.net/20.500.12110/paper_00144754_v39_n8_p894_Borda
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AT sterinbordal isprostacyclinsubservingavasodilatoreffectofmethoxamineinvolvingalphaadrenoreceptors
AT gimenomf isprostacyclinsubservingavasodilatoreffectofmethoxamineinvolvingalphaadrenoreceptors
AT lazzarim isprostacyclinsubservingavasodilatoreffectofmethoxamineinvolvingalphaadrenoreceptors
AT gimenoal isprostacyclinsubservingavasodilatoreffectofmethoxamineinvolvingalphaadrenoreceptors
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