Utility of base deficit, lactic acid, microalbuminuria, and C-reactive protein in the early detection of complications in the immediate postoperative evolution
Objective: To determine the utility of biochemical parameters such as lactic acid (LA), C-reactive protein (CRP), microalbuminuria (MAU), and base deficit (BD) as early markers of complications in the immediate postoperative evolution of elective open gastrointestinal surgeries. Design and Methods:...
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| Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_00099120_v37_n5_p404_Bianchi |
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todo:paper_00099120_v37_n5_p404_Bianchi2023-10-03T14:08:51Z Utility of base deficit, lactic acid, microalbuminuria, and C-reactive protein in the early detection of complications in the immediate postoperative evolution Bianchi, R.A. Silva, N.A. Natal, M.L. Romero, M.C. Biochemical markers Postoperative evolution C reactive protein lactic acid adult aged article chemical parameters controlled study early diagnosis female gastrointestinal surgery human major clinical study male microalbuminuria postoperative complication preoperative evaluation priority journal statistical significance Acid-Base Imbalance Adult Aged Albuminuria Argentina Biological Markers C-Reactive Protein Creatinine Digestive System Surgical Procedures Female Humans Lactic Acid Male Middle Aged Postoperative Complications Postoperative Period Predictive Value of Tests Prospective Studies Systemic Inflammatory Response Syndrome Objective: To determine the utility of biochemical parameters such as lactic acid (LA), C-reactive protein (CRP), microalbuminuria (MAU), and base deficit (BD) as early markers of complications in the immediate postoperative evolution of elective open gastrointestinal surgeries. Design and Methods: Sixty-two patients subject to elective open gastrointestinal surgery were evaluated during a period of 22 months. Results: From the initial 62 patients, 2 were excluded, 29 (48.3%) evolved without complications, and 31 (51.6%) with complications. It was observed that the most significant areas under the ROC curve corresponded to BD in the preoperative period, LA on the first day, and CRP from the second to the seventh day after surgery. MAU was not a discriminating parameter since it did not reach a significant area under the curve (AUC) at any time. Conclusions: The biochemical markers that best relate to the presence of complications are BD in the preoperative period, LA on the first day, and CRP from the second to the seventh day after surgery. © 2004 The Canadian Society of Clinical Chemists. All rights reserved. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_00099120_v37_n5_p404_Bianchi |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
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Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
Biochemical markers Postoperative evolution C reactive protein lactic acid adult aged article chemical parameters controlled study early diagnosis female gastrointestinal surgery human major clinical study male microalbuminuria postoperative complication preoperative evaluation priority journal statistical significance Acid-Base Imbalance Adult Aged Albuminuria Argentina Biological Markers C-Reactive Protein Creatinine Digestive System Surgical Procedures Female Humans Lactic Acid Male Middle Aged Postoperative Complications Postoperative Period Predictive Value of Tests Prospective Studies Systemic Inflammatory Response Syndrome |
| spellingShingle |
Biochemical markers Postoperative evolution C reactive protein lactic acid adult aged article chemical parameters controlled study early diagnosis female gastrointestinal surgery human major clinical study male microalbuminuria postoperative complication preoperative evaluation priority journal statistical significance Acid-Base Imbalance Adult Aged Albuminuria Argentina Biological Markers C-Reactive Protein Creatinine Digestive System Surgical Procedures Female Humans Lactic Acid Male Middle Aged Postoperative Complications Postoperative Period Predictive Value of Tests Prospective Studies Systemic Inflammatory Response Syndrome Bianchi, R.A. Silva, N.A. Natal, M.L. Romero, M.C. Utility of base deficit, lactic acid, microalbuminuria, and C-reactive protein in the early detection of complications in the immediate postoperative evolution |
| topic_facet |
Biochemical markers Postoperative evolution C reactive protein lactic acid adult aged article chemical parameters controlled study early diagnosis female gastrointestinal surgery human major clinical study male microalbuminuria postoperative complication preoperative evaluation priority journal statistical significance Acid-Base Imbalance Adult Aged Albuminuria Argentina Biological Markers C-Reactive Protein Creatinine Digestive System Surgical Procedures Female Humans Lactic Acid Male Middle Aged Postoperative Complications Postoperative Period Predictive Value of Tests Prospective Studies Systemic Inflammatory Response Syndrome |
| description |
Objective: To determine the utility of biochemical parameters such as lactic acid (LA), C-reactive protein (CRP), microalbuminuria (MAU), and base deficit (BD) as early markers of complications in the immediate postoperative evolution of elective open gastrointestinal surgeries. Design and Methods: Sixty-two patients subject to elective open gastrointestinal surgery were evaluated during a period of 22 months. Results: From the initial 62 patients, 2 were excluded, 29 (48.3%) evolved without complications, and 31 (51.6%) with complications. It was observed that the most significant areas under the ROC curve corresponded to BD in the preoperative period, LA on the first day, and CRP from the second to the seventh day after surgery. MAU was not a discriminating parameter since it did not reach a significant area under the curve (AUC) at any time. Conclusions: The biochemical markers that best relate to the presence of complications are BD in the preoperative period, LA on the first day, and CRP from the second to the seventh day after surgery. © 2004 The Canadian Society of Clinical Chemists. All rights reserved. |
| format |
JOUR |
| author |
Bianchi, R.A. Silva, N.A. Natal, M.L. Romero, M.C. |
| author_facet |
Bianchi, R.A. Silva, N.A. Natal, M.L. Romero, M.C. |
| author_sort |
Bianchi, R.A. |
| title |
Utility of base deficit, lactic acid, microalbuminuria, and C-reactive protein in the early detection of complications in the immediate postoperative evolution |
| title_short |
Utility of base deficit, lactic acid, microalbuminuria, and C-reactive protein in the early detection of complications in the immediate postoperative evolution |
| title_full |
Utility of base deficit, lactic acid, microalbuminuria, and C-reactive protein in the early detection of complications in the immediate postoperative evolution |
| title_fullStr |
Utility of base deficit, lactic acid, microalbuminuria, and C-reactive protein in the early detection of complications in the immediate postoperative evolution |
| title_full_unstemmed |
Utility of base deficit, lactic acid, microalbuminuria, and C-reactive protein in the early detection of complications in the immediate postoperative evolution |
| title_sort |
utility of base deficit, lactic acid, microalbuminuria, and c-reactive protein in the early detection of complications in the immediate postoperative evolution |
| url |
http://hdl.handle.net/20.500.12110/paper_00099120_v37_n5_p404_Bianchi |
| work_keys_str_mv |
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1807321207910957056 |