The effect of dolichol on the permeability properties of phosphatidylcholine bilayers

The permeability of liposomes to water, glucose, Ca2+ and alkaline cations was monitored by recording the change in absorbance at 450 nm using a rapid reaction stopped-flow spectrophotometer. Liposomes were prepared with egg phosphatidylcholine and concentrations of dolichol ranging from 0.1% to 9%...

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Autores principales:	Boscoboinik, D.O., Feliz, M., Disalvo, E.A., Belocopitow, E.
Formato:	JOUR
Materias:	dolichol permeability phosphatidylcholine bilayers phosphatidylcholine membrane permeability nonbiological model nonhuman phospholipid bilayer priority journal theoretical study Calcium Diterpenes Dolichol Glucose Lipid Bilayers Liposomes Permeability Phosphatidylcholines Potassium Temperature
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_00093084_v38_n4_p343_Boscoboinik
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

id	todo:paper_00093084_v38_n4_p343_Boscoboinik
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spelling	todo:paper_00093084_v38_n4_p343_Boscoboinik2023-10-03T14:08:37Z The effect of dolichol on the permeability properties of phosphatidylcholine bilayers Boscoboinik, D.O. Feliz, M. Disalvo, E.A. Belocopitow, E. dolichol permeability phosphatidylcholine bilayers dolichol phosphatidylcholine membrane permeability nonbiological model nonhuman phospholipid bilayer priority journal theoretical study Calcium Diterpenes Dolichol Glucose Lipid Bilayers Liposomes Permeability Phosphatidylcholines Potassium Temperature The permeability of liposomes to water, glucose, Ca2+ and alkaline cations was monitored by recording the change in absorbance at 450 nm using a rapid reaction stopped-flow spectrophotometer. Liposomes were prepared with egg phosphatidylcholine and concentrations of dolichol ranging from 0.1% to 9% (w/w). Net permeability of phosphatidylcholine bilayers to alkaline cations was induced by the incorporation of dolichol. This effect was not observed in the case of non-charged solutes like glucose or in that of alkaline earth cations such as calcium. Permeation of K+ was significantly increased above the phase transition temperature. These results suggest that dolichols may play a role in biological membranes, besides the well-known glycosyl carrier function in the biosynthesis of glycoproteins. © 1985. Fil:Boscoboinik, D.O. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Belocopitow, E. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_00093084_v38_n4_p343_Boscoboinik
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	dolichol permeability phosphatidylcholine bilayers dolichol phosphatidylcholine membrane permeability nonbiological model nonhuman phospholipid bilayer priority journal theoretical study Calcium Diterpenes Dolichol Glucose Lipid Bilayers Liposomes Permeability Phosphatidylcholines Potassium Temperature
spellingShingle	dolichol permeability phosphatidylcholine bilayers dolichol phosphatidylcholine membrane permeability nonbiological model nonhuman phospholipid bilayer priority journal theoretical study Calcium Diterpenes Dolichol Glucose Lipid Bilayers Liposomes Permeability Phosphatidylcholines Potassium Temperature Boscoboinik, D.O. Feliz, M. Disalvo, E.A. Belocopitow, E. The effect of dolichol on the permeability properties of phosphatidylcholine bilayers
topic_facet	dolichol permeability phosphatidylcholine bilayers dolichol phosphatidylcholine membrane permeability nonbiological model nonhuman phospholipid bilayer priority journal theoretical study Calcium Diterpenes Dolichol Glucose Lipid Bilayers Liposomes Permeability Phosphatidylcholines Potassium Temperature
description	The permeability of liposomes to water, glucose, Ca2+ and alkaline cations was monitored by recording the change in absorbance at 450 nm using a rapid reaction stopped-flow spectrophotometer. Liposomes were prepared with egg phosphatidylcholine and concentrations of dolichol ranging from 0.1% to 9% (w/w). Net permeability of phosphatidylcholine bilayers to alkaline cations was induced by the incorporation of dolichol. This effect was not observed in the case of non-charged solutes like glucose or in that of alkaline earth cations such as calcium. Permeation of K+ was significantly increased above the phase transition temperature. These results suggest that dolichols may play a role in biological membranes, besides the well-known glycosyl carrier function in the biosynthesis of glycoproteins. © 1985.
format	JOUR
author	Boscoboinik, D.O. Feliz, M. Disalvo, E.A. Belocopitow, E.
author_facet	Boscoboinik, D.O. Feliz, M. Disalvo, E.A. Belocopitow, E.
author_sort	Boscoboinik, D.O.
title	The effect of dolichol on the permeability properties of phosphatidylcholine bilayers
title_short	The effect of dolichol on the permeability properties of phosphatidylcholine bilayers
title_full	The effect of dolichol on the permeability properties of phosphatidylcholine bilayers
title_fullStr	The effect of dolichol on the permeability properties of phosphatidylcholine bilayers
title_full_unstemmed	The effect of dolichol on the permeability properties of phosphatidylcholine bilayers
title_sort	effect of dolichol on the permeability properties of phosphatidylcholine bilayers
url	http://hdl.handle.net/20.500.12110/paper_00093084_v38_n4_p343_Boscoboinik
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The effect of dolichol on the permeability properties of phosphatidylcholine bilayers

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